EC 1.6.2.4: NADPH-hemoprotein reductase

OxidoreductasesOpen in Browse

CatLog read 146 records for EC 1.6.2.4 from 10 papers, for 8 organisms. Names in these papers: NADPH-cytochrome P450 reductase (CPR), cytochrome P450 reductase (CPR), NADPH-cytochrome P450 oxidoreductase, CYP102A2 and 11 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 240 records for EC 1.6.2.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.6.2.4 in Browse.

Papers

Papers with records for EC 1.6.2.4
Paper	Organisms	Records
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium	Bacillus subtilis	30
Beta sheet 2-alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners	Rattus norvegicus	30
Differential contributions of NADPH-cytochrome P450 oxidoreductase FAD binding site residues to flavin binding and catalysis	—	18
Differential redox and electron-transfer properties of purified yeast, plant and human NADPH-cytochrome P-450 reductases highly modulate cytochrome P-450 activities	Arabidopsis thaliana, Homo sapiens and 1 more	15
Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase	Homo sapiens	14
Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis	Rattus norvegicus	11
Proximal FAD histidine residue influences interflavin electron transfer in cytochrome P450 reductase and methionine synthase reductase	Homo sapiens	9
Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1)	Rattus norvegicus	9
Molecular cloning and functional characterization of multiple NADPH-cytochrome P450 reductases from Andrographis paniculata	Andrographis paniculata	6
Cloning, expression and characterization of a fast self-sufficient P450: CYP102A5 from Bacillus cereus	Bacillus cereus, Bacillus megaterium and 1 more	4

Records

Records for EC 1.6.2.4 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
ApCPR1 (NADPH:cytochrome P450 reductase 1)	Andrographis paniculata	equine heart cytochrome c	5.592	0.07315	76.44 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR1 (NADPH:cytochrome P450 reductase 1), equine heart cytochrome c
ApCPR1 (NADPH:cytochrome P450 reductase 1)	Andrographis paniculata	NADPH	2.487	0.002223	1119 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR1 (NADPH:cytochrome P450 reductase 1), NADPH
ApCPR1 (NADPH:cytochrome P450 reductase 1)	Andrographis paniculata	potassium ferricyanide (potassium hexacyanoferrate(III))	9.865	0.0276	357 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR1 (NADPH:cytochrome P450 reductase 1), potassium ferricyanide (potassium hexacyanoferrate(III))
ApCPR2 (NADPH:cytochrome P450 reductase 2)	Andrographis paniculata	equine heart cytochrome c	1.232	0.01289	95.62 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR2 (NADPH:cytochrome P450 reductase 2), equine heart cytochrome c
ApCPR2 (NADPH:cytochrome P450 reductase 2)	Andrographis paniculata	NADPH	1.094	0.00367	298 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR2 (NADPH:cytochrome P450 reductase 2), NADPH
ApCPR2 (NADPH:cytochrome P450 reductase 2)	Andrographis paniculata	potassium ferricyanide (potassium hexacyanoferrate(III))	2.57	0.00724	355 calc.	pH 7.4, 25 °C	PMID 28410952	Open record: ApCPR2 (NADPH:cytochrome P450 reductase 2), potassium ferricyanide (potassium hexacyanoferrate(III))
CYP102A1	Bacillus megaterium	Linoleic acid	68.35	—	—	pH 7.4	PMID 17945181	Open record: CYP102A1, Linoleic acid
CYP102A2	Bacillus subtilis	12-methylmyristic acid	70.25	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, 12-methylmyristic acid
CYP102A2	Bacillus subtilis	13-methylmyristic acid	64.42	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, 13-methylmyristic acid
CYP102A2	Bacillus subtilis	14-methylpentadecanoic acid	79.8	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, 14-methylpentadecanoic acid
CYP102A2	Bacillus subtilis	15-methylpalmitic acid	101.8	0.0568	1.79 × 10³ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, 15-methylpalmitic acid
CYP102A2	Bacillus subtilis	arachidonic acid	101.3	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, arachidonic acid
CYP102A2	Bacillus subtilis	cytochrome c	190	0.0069	2.8 × 10⁴ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, cytochrome c
CYP102A2	Bacillus subtilis	ferricyanide	635.8	0.1534	4145 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, ferricyanide
CYP102A2	Bacillus subtilis	lauric acid	26.92	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, lauric acid
CYP102A2	Bacillus subtilis	linoleic acid	87.17	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, linoleic acid
CYP102A2	Bacillus subtilis	Linoleic acid	78	—	—	pH 7.4	PMID 17945181	Open record: CYP102A2, Linoleic acid
CYP102A2	Bacillus subtilis	NADH	30.8	17.9	1.72 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, NADH
CYP102A2	Bacillus subtilis	palmitic acid	3.33	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, palmitic acid
CYP102A2	Bacillus subtilis	phytanic acid	90.5	0.15	600 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, phytanic acid
CYP102A2	Bacillus subtilis	reduced nicotinamide adenine dinucleotide phosphate	192.7	0.0036	5.4 × 10⁴ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, reduced nicotinamide adenine dinucleotide phosphate
CYP102A2	Bacillus subtilis	stearic acid	7.17	0.0388	185 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, stearic acid
CYP102A2	Bacillus subtilis	tetradecanoic acid	0.68	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A2, tetradecanoic acid
CYP102A3	Bacillus subtilis	12-methylmyristic acid	34.25	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, 12-methylmyristic acid
CYP102A3	Bacillus subtilis	13-methylmyristic acid	36	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, 13-methylmyristic acid
CYP102A3	Bacillus subtilis	14-methylpentadecanoic acid	34.92	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, 14-methylpentadecanoic acid
CYP102A3	Bacillus subtilis	15-methylpalmitic acid	64.08	0.0683	938 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, 15-methylpalmitic acid
CYP102A3	Bacillus subtilis	arachidonic acid	28.2	0.079	360 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, arachidonic acid
CYP102A3	Bacillus subtilis	cytochrome c	58.7	0.0109	5.38 × 10³ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, cytochrome c
CYP102A3	Bacillus subtilis	ferricyanide	617.5	0.285	2.17 × 10³ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, ferricyanide
CYP102A3	Bacillus subtilis	lauric acid	1.73	0.165	10.5 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, lauric acid
CYP102A3	Bacillus subtilis	linoleic acid	18.5	—	—	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, linoleic acid
CYP102A3	Bacillus subtilis	NADH	1.59	2.43	0.654 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, NADH
CYP102A3	Bacillus subtilis	palmitic acid	11.27	0.337	33.4 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, palmitic acid
CYP102A3	Bacillus subtilis	phytanic acid	13.23	0.0287	461 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, phytanic acid
CYP102A3	Bacillus subtilis	reduced nicotinamide adenine dinucleotide phosphate	58.8	0.0051	1.2 × 10⁴ calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, reduced nicotinamide adenine dinucleotide phosphate
CYP102A3	Bacillus subtilis	stearic acid	6.23	0.0685	91.0 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, stearic acid
CYP102A3	Bacillus subtilis	tetradecanoic acid	9.27	0.542	17.1 calc.	pH 7.4, 30 °C	PMID 15122913	Open record: CYP102A3, tetradecanoic acid
CYP102A5	Bacillus cereus	Linoleic acid	112.2	—	—	pH 7.4	PMID 17945181	Open record: CYP102A5, Linoleic acid
CYP102A5	Bacillus cereus	Palmitic acid	9.8	0.23	43 calc.	pH 7.4	PMID 17945181	Open record: CYP102A5, Palmitic acid
cytochrome P450 reductase (CPR)	Homo sapiens	ferricyanide	43.5	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR), ferricyanide
cytochrome P450 reductase (CPR)	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	30	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR), hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)	Homo sapiens	NADPH	20	7 × 10⁻⁴	2.82 × 10⁴	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR), NADPH
cytochrome P450 reductase (CPR)	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphatecytochrome c3+ reduction followed at 550 nm	20	7.1 × 10⁻⁴	2.82 × 10⁴	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR), reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphate	1.1	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR), reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)variant A635G	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	72.9	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant A635G, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant A635G	Homo sapiens	NADPH	23.4	0.00106	2.21 × 10⁴	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant A635G, NADPH
cytochrome P450 reductase (CPR)variant A635G/R636S	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	76.5	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant A635G/R636S, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant A635G/R636S	Homo sapiens	NADPH	38.6	0.0018	2.21 × 10⁴	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant A635G/R636S, NADPH
cytochrome P450 reductase (CPR)variant D634A	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	0.54	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant D634A, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant D634A	Homo sapiens	NADPH	0.56	1.9 × 10⁻⁴	2.9 × 10³	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant D634A, NADPH
cytochrome P450 reductase (CPR)variant D634N	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	1.8	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant D634N, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant D634N	Homo sapiens	NADPH	2.21	1.4 × 10⁻⁴	1.58 × 10⁴	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant D634N, NADPH
cytochrome P450 reductase (CPR)variant H322A	Homo sapiens	ferricyanide	18.1	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322A, ferricyanide
cytochrome P450 reductase (CPR)variant H322A	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphatecytochrome c3+ reduction followed at 550 nm	5.4	3.1 × 10⁻⁴	1.74 × 10⁴	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322A, reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)variant H322A	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphate	0.71	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322A, reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)variant H322Q	Homo sapiens	ferricyanide	26.1	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322Q, ferricyanide
cytochrome P450 reductase (CPR)variant H322Q	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphatecytochrome c3+ reduction followed at 550 nm	11.3	5.8 × 10⁻⁴	1.94 × 10⁴	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322Q, reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)variant H322Q	Homo sapiens	reduced nicotinamide adenine dinucleotide phosphate	1	—	—	pH 7.5, 25 °C	PMID 24589657	Open record: cytochrome P450 reductase (CPR) variant H322Q, reduced nicotinamide adenine dinucleotide phosphate
cytochrome P450 reductase (CPR)variant R636A	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	63.2	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant R636A, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant R636A	Homo sapiens	NADPH	28	0.0016	1.75 × 10⁴	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant R636A, NADPH
cytochrome P450 reductase (CPR)variant R636S	Homo sapiens	hexacyanoferrate(III) (ferricyanide)	49.5	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant R636S, hexacyanoferrate(III) (ferricyanide)
cytochrome P450 reductase (CPR)variant R636S	Homo sapiens	NADPH	30.5	—	—	pH 7.5, 25 °C	PMID 27461959	Open record: cytochrome P450 reductase (CPR) variant R636S, NADPH
NADPH-cytochrome P-450 oxidoreductase	Rattus norvegicus	cytochrome c	—	0.0178	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase, cytochrome c
NADPH-cytochrome P-450 oxidoreductase	Rattus norvegicus	cytochrome cmembrane-bound	—	0.0211	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase, cytochrome c
NADPH-cytochrome P-450 oxidoreductase	Rattus norvegicus	NADPH	—	0.0064	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase, NADPH
NADPH-cytochrome P-450 oxidoreductasevariant Y140D (Asp-140)	Rattus norvegicus	cytochrome c	—	0.0191	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y140D (Asp-140), cytochrome c
NADPH-cytochrome P-450 oxidoreductasevariant Y140D (Asp-140)	Rattus norvegicus	NADPH	—	0.0066	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y140D (Asp-140), NADPH
NADPH-cytochrome P-450 oxidoreductasevariant Y140F (Phe-140)	Rattus norvegicus	NADPH	—	0.0078	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y140F (Phe-140), NADPH
NADPH-cytochrome P-450 oxidoreductasevariant Y140F/Y178F (Phe-140/Phe-178)	Rattus norvegicus	cytochrome c	—	0.0131	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y140F/Y178F (Phe-140/Phe-178), cytochrome c
NADPH-cytochrome P-450 oxidoreductasevariant Y140F/Y178F (Phe-140/Phe-178)	Rattus norvegicus	NADPH	—	0.0114	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y140F/Y178F (Phe-140/Phe-178), NADPH
NADPH-cytochrome P-450 oxidoreductasevariant Y178D (Asp-178)	Rattus norvegicus	NADPH	—	0.0095	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y178D (Asp-178), NADPH
NADPH-cytochrome P-450 oxidoreductasevariant Y178F (Phe-178)	Rattus norvegicus	cytochrome c	—	0.014	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y178F (Phe-178), cytochrome c
NADPH-cytochrome P-450 oxidoreductasevariant Y178F (Phe-178)	Rattus norvegicus	NADPH	—	0.0071	—	pH 7.7, 28 °C	PMID 2708380	Open record: NADPH-cytochrome P-450 oxidoreductase variant Y178F (Phe-178), NADPH
NADPH-cytochrome P-450 reductase (HSR1)	Homo sapiens	dichloroindophenol	22	—	3.6 × 10³	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (HSR1), dichloroindophenol
NADPH-cytochrome P-450 reductase (HSR1)	Homo sapiens	ferricyanide	110	—	1.2 × 10⁴	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (HSR1), ferricyanide
NADPH-cytochrome P-450 reductase (HSR1)	Homo sapiens	horse-heart cytochrome c	48	0.032	1.5 × 10³ calc.	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (HSR1), horse-heart cytochrome c
NADPH-cytochrome P-450 reductase (HSR1)	Homo sapiens	NADPH	—	4.6 × 10⁻⁴	—	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (HSR1), NADPH
NADPH-cytochrome P-450 reductase (SCR1)	Saccharomyces cerevisiae	dichloroindophenol	8.8	—	1.4 × 10³	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (SCR1), dichloroindophenol
NADPH-cytochrome P-450 reductase (SCR1)	Saccharomyces cerevisiae	ferricyanide	200	—	1.3 × 10³	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (SCR1), ferricyanide
NADPH-cytochrome P-450 reductase (SCR1)	Saccharomyces cerevisiae	horse-heart cytochrome c	200	0.021	9.5 × 10³ calc.	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (SCR1), horse-heart cytochrome c
NADPH-cytochrome P-450 reductase (SCR1)	Saccharomyces cerevisiae	NADPH	—	0.0032	—	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase (SCR1), NADPH
NADPH-cytochrome P-450 reductase ATR1	Arabidopsis thaliana	dichloroindophenol	19	—	5.8 × 10³	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR1, dichloroindophenol
NADPH-cytochrome P-450 reductase ATR1	Arabidopsis thaliana	ferricyanide	200	—	3.5 × 10³	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR1, ferricyanide
NADPH-cytochrome P-450 reductase ATR1	Arabidopsis thaliana	horse-heart cytochrome c	213	0.017	1.3 × 10⁴ calc.	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR1, horse-heart cytochrome c
NADPH-cytochrome P-450 reductase ATR1	Arabidopsis thaliana	NADPH	—	0.0022	—	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR1, NADPH
NADPH-cytochrome P-450 reductase ATR2	Arabidopsis thaliana	dichloroindophenol	8	—	380	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR2, dichloroindophenol
NADPH-cytochrome P-450 reductase ATR2	Arabidopsis thaliana	ferricyanide	320	—	900	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR2, ferricyanide
NADPH-cytochrome P-450 reductase ATR2	Arabidopsis thaliana	horse-heart cytochrome c	14	0.016	880 calc.	pH 7, 25 °C	PMID 9990323	Open record: NADPH-cytochrome P-450 reductase ATR2, horse-heart cytochrome c
NADPH-cytochrome P450 oxidoreductase	—	cytochrome c	—	0.0163	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase, cytochrome c
NADPH-cytochrome P450 oxidoreductase	—	NADPH	—	0.0062	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase, NADPH
NADPH-cytochrome P450 oxidoreductasevariant C472T	—	cytochrome c	—	0.0217	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant C472T, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant C472T	—	NADPH	—	0.0063	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant C472T, NADPH
NADPH-cytochrome P450 oxidoreductasevariant G488L	—	cytochrome c	—	0.0134	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant G488L, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant G488L	—	NADPH	—	0.0077	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant G488L, NADPH
NADPH-cytochrome P450 oxidoreductasevariant R454E	—	cytochrome c	—	0.0166	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant R454E, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant R454E	—	NADPH	—	0.0041	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant R454E, NADPH
NADPH-cytochrome P450 oxidoreductasevariant S678X	—	cytochrome c	—	0.0199	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant S678X, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant S678X	—	NADPH	—	0.0056	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant S678X, NADPH
NADPH-cytochrome P450 oxidoreductasevariant T491V	—	cytochrome c	—	0.0201	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant T491V, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant T491V	—	NADPH	—	0.0059	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant T491V, NADPH
NADPH-cytochrome P450 oxidoreductasevariant W677X	—	cytochrome c	—	0.0085	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant W677X, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant W677X	—	NADPH	—	0.0015	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant W677X, NADPH
NADPH-cytochrome P450 oxidoreductasevariant W677Y	—	cytochrome c	—	0.0143	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant W677Y, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant W677Y	—	NADPH	—	0.0028	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant W677Y, NADPH
NADPH-cytochrome P450 oxidoreductasevariant Y456S	—	cytochrome c	—	0.0548	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant Y456S, cytochrome c
NADPH-cytochrome P450 oxidoreductasevariant Y456S	—	NADPH	—	0.0058	—	pH 7.7, 28 °C	PMID 11022049	Open record: NADPH-cytochrome P450 oxidoreductase variant Y456S, NADPH
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 10 mM	5.8	0.0022	2.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 30 mM	8.5	0.0031	2.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 60 mM	12	0.0039	3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 110 mM	18	0.0062	3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 210 mM	28	0.01	2.8 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 30 mM	17	0.002	8.3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 60 mM	14.7	0.004	3.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 110 mM	20	0.0085	2.3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 210 mM	33	0.02	1.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 310 mM	35	0.023	1.52 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 10 mM	10.5	0.0021	5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 30 mM	13.8	0.0026	5.3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 60 mM	20	0.0041	4.8 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 110 mM	30	0.0063	4.8 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 210 mM	40	0.0087	4.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 30 mM	25	0.0025	1 × 10⁴	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 60 mM	23	0.0052	4.5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 110 mM	37	0.011	3.3 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 210 mM	65	0.026	2.5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/D113A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 310 mM	55	0.025	2.2 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/D113A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 10 mM	13	0.0018	7.2 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 30 mM	18	0.0026	6.8 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 60 mM	25	0.0038	6.5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 110 mM	38	0.0065	5.8 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideKCl added to give ionic strength 210 mM	57	0.011	5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 30 mM	25	0.0024	1.05 × 10⁴	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 60 mM	25	0.0036	7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 110 mM	37	0.006	6 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 210 mM	58	0.013	4.5 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH-cytochrome P450 reductase (CPR)variant K56Q/E115A/E116A	Rattus norvegicus	cytochrome c (horse heart), oxidized form (cyt c^{3+})KCl added to give ionic strength 310 mM	58	0.016	3.7 × 10³	pH 7.5, 25 °C	PMID 20152939	Open record: NADPH-cytochrome P450 reductase (CPR) variant K56Q/E115A/E116A, cytochrome c (horse heart), oxidized form (cyt c^{3+})
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	1,2,4-Benzotriazine-1-oxide	—	—	17	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 1,2,4-Benzotriazine-1-oxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	2-CF_3-quinoxaline-1,4-dioxide	—	—	27	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 2-CF_3-quinoxaline-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	2-NH_2-3-CN-quinoxaline-1,4-dioxide	—	—	4.7	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 2-NH_2-3-CN-quinoxaline-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	3-CF_3SO_2NH-1,2,4-benzotriazine-1,4-dioxide	—	—	25	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 3-CF_3SO_2NH-1,2,4-benzotriazine-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	3-CH_3CONH-1,2,4-benzotriazine-1,4-dioxide	—	—	70	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 3-CH_3CONH-1,2,4-benzotriazine-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	3-CH_3CONH-1,2,4-benzotriazine-1-oxide	—	—	8.7	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 3-CH_3CONH-1,2,4-benzotriazine-1-oxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	3-CH_3OCONH-1,2,4-benzotriazine-1,4-dioxide	—	—	80	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 3-CH_3OCONH-1,2,4-benzotriazine-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	3-CH_3SO_2NH-1,2,4-benzotriazine-1,4-dioxide	—	—	2.7	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 3-CH_3SO_2NH-1,2,4-benzotriazine-1,4-dioxide
NADPH:cytochrome P-450 reductase (P-450R)	Rattus norvegicus	7-CF_3O-tirapazamine	—	—	46	pH 7, 25 °C	PMID 33228195	Open record: NADPH:cytochrome P-450 reductase (P-450R), 7-CF_3O-tirapazamine