CatLogenzyme kinetics catalog

EC 2.7.1.147: ADP-specific glucose/glucosamine kinase

TransferasesOpen in Browse

CatLog read 37 records for EC 2.7.1.147 from 7 papers, for 7 organisms. Names in these papers: ADP-dependent glucokinase (TlGK), ADP-dependent glucokinase (pfGK), ADP-dependent glucokinase (tlGK), ADP-dependent glucokinase TK1110 (glucosamine kinase) and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 17 records for EC 2.7.1.147 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.147 in Browse.

Papers

PaperOrganismsRecords
Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaeaPyrococcus furiosus, Thermococcus litoralis10
Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralisThermococcus litoralis10
Identification of the glucosamine kinase in the chitinolytic pathway of Thermococcus kodakarensisThermococcus kodakarensis5
Bifunctional ADP-dependent phosphofructokinase/glucokinase activity in the order Methanococcales--biochemical characterization of the mesophilic enzyme from Methanococcus maripaludisMethanococcus maripaludis4
ADP-dependent phosphofructokinases from the archaeal order Methanosarcinales display redundant glucokinase activityMethanococcoides burtonii, Methanohalobium evestigatum4
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinasesMethanococcus jannaschii, Thermococcus litoralis3
ADP-Dependent Kinases From the Archaeal Order Methanosarcinales Adapt to Salt by a Non-canonical Evolutionarily Conserved Strategy—1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
ADP-dependent glucokinase (pfGK)Pyrococcus furiosuscobalt(II)-ADP complex1140.0254.6 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (pfGK)Pyrococcus furiosusmagnesium-ADP complexMgADP varied; free Mg2+ held at 1 mM1040.0147.4 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (pfGK)Pyrococcus furiosusmagnesium-ADP complexMgADP varied at several free ADP concentrations1390.00463.0 × 10⁴ calc.pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (pfGK)Pyrococcus furiosusmanganese(II)-ADP complexMnADP varied; free Mn2+ held at 1 mM1160.0225.3 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (pfGK)Pyrococcus furiosusmanganese(II)-ADP complexMnADP varied at several free Mn2+ concentrations2550.0289.1 × 10³ calc.pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (tlGK)Thermococcus litoraliscobalt(II)-ADP complex440.0152.9 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (TlGK)Thermococcus litoralisD-glucose580.28207pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)Thermococcus litoralisD-glucose420.4495pH 7.8, 40 °CPMID 28726643Open
ADP-dependent glucokinase (TlGK)Thermococcus litoralismagnesium adenosine 5'-diphosphate (MgADP-)—0.0144.14 × 10³pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (tlGK)Thermococcus litoralismagnesium-ADP complexMgADP varied; free Mg2+ held at 1 mM350.0231.5 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (tlGK)Thermococcus litoralismagnesium-ADP complexMgADP varied at several free ADP concentrations510.00212.4 × 10⁴ calc.pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (tlGK)Thermococcus litoralismanganese(II)-ADP complexMnADP varied; free Mn2+ held at 1 mM210.0171.2 × 10³pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (tlGK)Thermococcus litoralismanganese(II)-ADP complexMnADP varied at several free Mn2+ concentrations250.0112.3 × 10³ calc.pH 7.8, 40 °CPMID 21906652Open
ADP-dependent glucokinase (TlGK)variant E279DThermococcus litoralisD-glucose1.5280.19pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E279DThermococcus litoralismagnesium adenosine 5'-diphosphate (MgADP-)—0.275.63pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E279LThermococcus litoralisD-glucose0.56109.70.0051pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E279LThermococcus litoralismagnesium adenosine 5'-diphosphate (MgADP-)—0.03416.4pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E279QThermococcus litoralisD-glucose0.718.90.079pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E279QThermococcus litoralismagnesium adenosine 5'-diphosphate (MgADP-)—0.06610.7pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E308QThermococcus litoralisD-glucose4.30.3911pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase (TlGK)variant E308QThermococcus litoralismagnesium adenosine 5'-diphosphate (MgADP-)—1.462.95pH 7.8, 40 °CPMID 26428088Open
ADP-dependent glucokinase TK1110 (glucosamine kinase)Thermococcus kodakarensisadenosine 5'-diphosphate2100.082.6 × 10³ calc.pH 7.5, 70 °CPMID 29146530Open
ADP-dependent glucokinase TK1110 (glucosamine kinase)Thermococcus kodakarensisD-glucosamineTable 11200.33360 calc.pH 7.5, 70 °CPMID 29146530Open
ADP-dependent glucokinase TK1110 (glucosamine kinase)Thermococcus kodakarensisD-glucosaminein the text——360pH 7.5, 70 °CPMID 29146530Open
ADP-dependent glucokinase TK1110 (glucosamine kinase)Thermococcus kodakarensisD-glucoseTable 12480.77320 calc.pH 7.5, 70 °CPMID 29146530Open
ADP-dependent glucokinase TK1110 (glucosamine kinase)Thermococcus kodakarensisD-glucosein the text——320pH 7.5, 70 °CPMID 29146530Open
ADP-dependent phosphofructokinase/glucokinase (MbPFK)Methanococcoides burtoniiadenosine 5'-diphosphate0.80.6411pH 7.8, 25 °CPMID 28919057Open
ADP-dependent phosphofructokinase/glucokinase (MbPFK)Methanococcoides burtoniiD-glucose0.9200.036pH 7.8, 25 °CPMID 28919057Open
ADP-dependent phosphofructokinase/glucokinase (MePFK)Methanohalobium evestigatumadenosine 5'-diphosphate21.51.3pH 7.8, 40 °CPMID 28919057Open
ADP-dependent phosphofructokinase/glucokinase (MePFK)Methanohalobium evestigatumD-glucose1.9110.18pH 7.8, 40 °CPMID 28919057Open
ADP-dependent phosphofructokinase/glucokinase, last common ancestor of Methanosarcinales (AncMsPFK/GK)variant ancestral reconstructed sequence (AncMsPFK/GK)—D-glucose3.61340.00548pH 7.8, 40 °CPMID 29997580Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MjPFK/GK)Methanococcus jannaschiiD-fructose 6-phosphate2.70.0063420pH 6.5, 40 °CPMID 28726643Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MjPFK/GK)Methanococcus jannaschiiD-glucose51.14.5pH 7.8, 40 °CPMID 28726643Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MmPFK/GK)Methanococcus maripaludisD-glucose23400.575pH 7.8, 30 °CPMID 24860874Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MmPFK/GK)Methanococcus maripaludisglucose 6-phosphate0.6780.6231.09pH 7, 30 °CPMID 24860874Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MmPFK/GK)Methanococcus maripaludisMg2+-ADPMgCl2 5 mM in excess over ADP (approx. 5 mM free Mg2+)48163pH 7.8, 30 °CPMID 24860874Open
bifunctional ADP-dependent phosphofructokinase/glucokinase (MmPFK/GK)Methanococcus maripaludisMg2+-ADPapprox. 1 mM free Mg2+ (Kd 676 µM for Mg-ADP used)—0.3—pH 7.8, 30 °CPMID 24860874Open