EC 2.7.2.4: aspartate kinase

TransferasesOpen in Browse

CatLog read 144 records for EC 2.7.2.4 from 10 papers, for 6 organisms. Names in these papers: aspartate kinase, aspartate kinase (AK_{Sc}), aspartate kinase III, aspartokinase III (AKIII) and 15 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 69 records for EC 2.7.2.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.2.4 in Browse.

Papers

Papers with records for EC 2.7.2.4
Paper	Organisms	Records
Kinetic and mutation analyses of aspartate kinase from Thermus flavus	Thermus flavus	56
Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase	Saccharomyces cerevisiae	26
Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid	Escherichia coli	15
Site-directed mutagenesis of Escherichia coli acetylglutamate kinase and aspartokinase III probes the catalytic and substrate-binding mechanisms of these amino acid kinase family enzymes and allows…	Escherichia coli	10
Allosteric monofunctional aspartate kinases from Arabidopsis	Arabidopsis thaliana	8
Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms. Physiological context sets the specificity	Arabidopsis thaliana	7
Production and characterization of bifunctional enzymes. Domain swapping to produce new bifunctional enzymes in the aspartate pathway	Escherichia coli	6
Conversion of feedback regulation in aspartate kinase by domain exchange	Bacillus subtilis	6
Threonine-insensitive homoserine dehydrogenase from soybean: genomic organization, kinetic mechanism, and in vivo activity	Glycine max	6
An integrated study of threonine-pathway enzyme kinetics in Escherichia coli	Escherichia coli	4

Records

Records for EC 2.7.2.4 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
aspartate kinase	Thermus flavus	adenosine 5'-triphosphate	—	0.5	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase, adenosine 5'-triphosphate
aspartate kinase	Thermus flavus	L-aspartic acid	25	0.27	93 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase, L-aspartic acid
aspartate kinasevariant A157L	Thermus flavus	adenosine 5'-triphosphate	—	0.45	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A157L, adenosine 5'-triphosphate
aspartate kinasevariant A157L	Thermus flavus	L-aspartic acid	4.7	0.19	25 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A157L, L-aspartic acid
aspartate kinasevariant A189L	Thermus flavus	adenosine 5'-triphosphate	—	0.98	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A189L, adenosine 5'-triphosphate
aspartate kinasevariant A189L	Thermus flavus	L-aspartic acid	6	0.45	13 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A189L, L-aspartic acid
aspartate kinasevariant A23L	Thermus flavus	adenosine 5'-triphosphate	—	0.72	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A23L, adenosine 5'-triphosphate
aspartate kinasevariant A23L	Thermus flavus	L-aspartic acid	24.3	0.65	37 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A23L, L-aspartic acid
aspartate kinasevariant A42S	Thermus flavus	adenosine 5'-triphosphate	—	1.02	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A42S, adenosine 5'-triphosphate
aspartate kinasevariant A42S	Thermus flavus	L-aspartic acid	23.2	0.6	39 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant A42S, L-aspartic acid
aspartate kinasevariant D154A	Thermus flavus	adenosine 5'-triphosphate	—	1.05	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D154A, adenosine 5'-triphosphate
aspartate kinasevariant D154A	Thermus flavus	L-aspartic acid	1.8	1.2	1.5 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D154A, L-aspartic acid
aspartate kinasevariant D154N	Thermus flavus	adenosine 5'-triphosphate	—	0.63	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D154N, adenosine 5'-triphosphate
aspartate kinasevariant D154N	Thermus flavus	L-aspartic acid	2.17	0.47	4.6 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D154N, L-aspartic acid
aspartate kinasevariant D174A	Thermus flavus	adenosine 5'-triphosphate	—	0.43	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D174A, adenosine 5'-triphosphate
aspartate kinasevariant D174A	Thermus flavus	L-aspartic acid	3	0.53	5.7 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D174A, L-aspartic acid
aspartate kinasevariant D182A	Thermus flavus	adenosine 5'-triphosphate	—	2.45	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D182A, adenosine 5'-triphosphate
aspartate kinasevariant D182A	Thermus flavus	L-aspartic acid	2.2	1.31	1.7 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant D182A, L-aspartic acid
aspartate kinasevariant E202A	Thermus flavus	adenosine 5'-triphosphate	—	0.29	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant E202A, adenosine 5'-triphosphate
aspartate kinasevariant E202A	Thermus flavus	L-aspartic acid	4	0.27	15 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant E202A, L-aspartic acid
aspartate kinasevariant F136A	Thermus flavus	adenosine 5'-triphosphate	—	0.57	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant F136A, adenosine 5'-triphosphate
aspartate kinasevariant F136A	Thermus flavus	L-aspartic acid	17	5.29	3.2 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant F136A, L-aspartic acid
aspartate kinasevariant G10A	Thermus flavus	adenosine 5'-triphosphate	—	3.57	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G10A, adenosine 5'-triphosphate
aspartate kinasevariant G10A	Thermus flavus	L-aspartic acid	2.8	1.34	2.1 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G10A, L-aspartic acid
aspartate kinasevariant G135A	Thermus flavus	adenosine 5'-triphosphate	—	0.52	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G135A, adenosine 5'-triphosphate
aspartate kinasevariant G135A	Thermus flavus	L-aspartic acid	0.97	1.34	0.72 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G135A, L-aspartic acid
aspartate kinasevariant G149A	Thermus flavus	adenosine 5'-triphosphate	—	0.41	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G149A, adenosine 5'-triphosphate
aspartate kinasevariant G149A	Thermus flavus	L-aspartic acid	13.3	0.36	37 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G149A, L-aspartic acid
aspartate kinasevariant G152A	Thermus flavus	adenosine 5'-triphosphate	—	0.5	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G152A, adenosine 5'-triphosphate
aspartate kinasevariant G152A	Thermus flavus	L-aspartic acid	4.3	0.42	10 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G152A, L-aspartic acid
aspartate kinasevariant G177A	Thermus flavus	adenosine 5'-triphosphate	—	0.27	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G177A, adenosine 5'-triphosphate
aspartate kinasevariant G177A	Thermus flavus	L-aspartic acid	13.3	0.34	39 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G177A, L-aspartic acid
aspartate kinasevariant G73A	Thermus flavus	adenosine 5'-triphosphate	—	1.28	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G73A, adenosine 5'-triphosphate
aspartate kinasevariant G73A	Thermus flavus	L-aspartic acid	32	0.61	52 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant G73A, L-aspartic acid
aspartate kinasevariant I171A	Thermus flavus	adenosine 5'-triphosphate	—	0.6	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant I171A, adenosine 5'-triphosphate
aspartate kinasevariant I171A	Thermus flavus	L-aspartic acid	10.8	0.37	29 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant I171A, L-aspartic acid
aspartate kinasevariant L148A	Thermus flavus	adenosine 5'-triphosphate	—	0.97	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant L148A, adenosine 5'-triphosphate
aspartate kinasevariant L148A	Thermus flavus	L-aspartic acid	23	2.1	11 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant L148A, L-aspartic acid
aspartate kinasevariant P183A	Thermus flavus	adenosine 5'-triphosphate	—	1.9	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant P183A, adenosine 5'-triphosphate
aspartate kinasevariant P183A	Thermus flavus	L-aspartic acid	4.3	1.2	3.6 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant P183A, L-aspartic acid
aspartate kinasevariant R150A	Thermus flavus	adenosine 5'-triphosphate	—	0.46	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant R150A, adenosine 5'-triphosphate
aspartate kinasevariant R150A	Thermus flavus	L-aspartic acid	1.8	1.23	1.5 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant R150A, L-aspartic acid
aspartate kinasevariant S12A	Thermus flavus	adenosine 5'-triphosphate	—	0.52	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S12A, adenosine 5'-triphosphate
aspartate kinasevariant S12A	Thermus flavus	L-aspartic acid	24.7	0.32	77 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S12A, L-aspartic acid
aspartate kinasevariant S153A	Thermus flavus	adenosine 5'-triphosphate	—	0.44	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S153A, adenosine 5'-triphosphate
aspartate kinasevariant S153A	Thermus flavus	L-aspartic acid	12.3	0.47	26 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S153A, L-aspartic acid
aspartate kinasevariant S41A	Thermus flavus	adenosine 5'-triphosphate	—	1.39	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S41A, adenosine 5'-triphosphate
aspartate kinasevariant S41A	Thermus flavus	L-aspartic acid	0.8	0.41	2.0 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant S41A, L-aspartic acid
aspartate kinasevariant T238A	Thermus flavus	adenosine 5'-triphosphate	—	0.56	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant T238A, adenosine 5'-triphosphate
aspartate kinasevariant T238A	Thermus flavus	L-aspartic acid	7.3	0.39	19 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant T238A, L-aspartic acid
aspartate kinasevariant T47A	Thermus flavus	adenosine 5'-triphosphate	—	2.1	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant T47A, adenosine 5'-triphosphate
aspartate kinasevariant T47A	Thermus flavus	L-aspartic acid	6.7	19.5	0.34 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant T47A, L-aspartic acid
aspartate kinasevariant V39A	Thermus flavus	adenosine 5'-triphosphate	—	0.89	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant V39A, adenosine 5'-triphosphate
aspartate kinasevariant V39A	Thermus flavus	L-aspartic acid	32	0.33	97 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant V39A, L-aspartic acid
aspartate kinasevariant Y8A	Thermus flavus	adenosine 5'-triphosphate	—	0.86	—	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant Y8A, adenosine 5'-triphosphate
aspartate kinasevariant Y8A	Thermus flavus	L-aspartic acid	13.8	0.32	43 calc.	pH 7.5, 60 °C	PMID 16232547	Open record: aspartate kinase variant Y8A, L-aspartic acid
aspartate kinase (AK_{Sc})	Saccharomyces cerevisiae	adenosine 5'-triphosphate	49.3	0.74	66.6	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}), adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})	Saccharomyces cerevisiae	L-aspartate	46.6	4.59	10.2	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}), L-aspartate
aspartate kinase (AK_{Sc})variant E254A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	4.43	0.7	6.33	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant E254A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant E254A	Saccharomyces cerevisiae	L-aspartate	5.14	9.77	0.526	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant E254A, L-aspartate
aspartate kinase (AK_{Sc})variant E279A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	1.13	1.15	0.983	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant E279A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant E279A	Saccharomyces cerevisiae	L-aspartate	0.98	2.33	0.421	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant E279A, L-aspartate
aspartate kinase (AK_{Sc})variant H292A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	0.41	3.36	0.121	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H292A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant H292A	Saccharomyces cerevisiae	L-aspartate	2.49	6.81	0.366	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H292A, L-aspartate
aspartate kinase (AK_{Sc})variant H292Q	Saccharomyces cerevisiae	adenosine 5'-triphosphate	8.3	1.45	0.572	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H292Q, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant H292Q	Saccharomyces cerevisiae	L-aspartate	10.3	11.9	0.864	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H292Q, L-aspartate
aspartate kinase (AK_{Sc})variant H497A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	7.33	1.26	5.82	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H497A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant H497A	Saccharomyces cerevisiae	L-aspartate	6.92	8.66	0.797	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant H497A, L-aspartate
aspartate kinase (AK_{Sc})variant K18A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	0.53	0.89	0.602	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant K18A	Saccharomyces cerevisiae	L-aspartate	0.41	3.21	0.129	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18A, L-aspartate
aspartate kinase (AK_{Sc})variant K18Q	Saccharomyces cerevisiae	adenosine 5'-triphosphate	0.6	0.61	0.977	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18Q, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant K18Q	Saccharomyces cerevisiae	L-aspartate	0.54	4.25	0.127	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18Q, L-aspartate
aspartate kinase (AK_{Sc})variant K18R	Saccharomyces cerevisiae	adenosine 5'-triphosphate	0.31	0.26	1.22	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18R, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant K18R	Saccharomyces cerevisiae	L-aspartate	0.3	1.63	0.184	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant K18R, L-aspartate
aspartate kinase (AK_{Sc})variant R419A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	5.55	2.4	2.31	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant R419A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant R419A	Saccharomyces cerevisiae	L-aspartate	4.65	3.25	1.43	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant R419A, L-aspartate
aspartate kinase (AK_{Sc})variant S23A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	19.1	1.05	18.2	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant S23A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant S23A	Saccharomyces cerevisiae	L-aspartate	17.9	6.99	2.56	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant S23A, L-aspartate
aspartate kinase (AK_{Sc})variant T22A	Saccharomyces cerevisiae	adenosine 5'-triphosphate	56.9	3.1	18.3	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant T22A, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant T22A	Saccharomyces cerevisiae	L-aspartate	45	7.08	6.35	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant T22A, L-aspartate
aspartate kinase (AK_{Sc})variant T295V	Saccharomyces cerevisiae	adenosine 5'-triphosphate	23.3	2.35	9.91	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant T295V, adenosine 5'-triphosphate
aspartate kinase (AK_{Sc})variant T295V	Saccharomyces cerevisiae	L-aspartate	18	3.19	5.64	pH 7.5, 30 °C	PMID 14623312	Open record: aspartate kinase (AK_{Sc}) variant T295V, L-aspartate
aspartate kinase 1 (AK1)	Arabidopsis thaliana	ATP	—	1.7	—	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 1 (AK1), ATP
aspartate kinase 1 (AK1)	Arabidopsis thaliana	L-aspartate50 mM Hepes; 100 nM AK	23.4	2.037	11.5 calc.	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 1 (AK1), L-aspartate
aspartate kinase 1 (AK1)	Arabidopsis thaliana	L-aspartatebuffer D: 50 mM Hepes; bisubstrate variation experiments	25	—	—	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 1 (AK1), L-aspartate
aspartate kinase 2 (AK2)	Arabidopsis thaliana	ATP	—	0.98	—	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 2 (AK2), ATP
aspartate kinase 2 (AK2)	Arabidopsis thaliana	L-aspartate50 mM Hepes; 100 nM AK	14.5	1.94	7.47 calc.	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 2 (AK2), L-aspartate
aspartate kinase 2 (AK2)	Arabidopsis thaliana	L-aspartatebuffer D: 50 mM Hepes; bisubstrate variation experiments	14	—	—	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 2 (AK2), L-aspartate
aspartate kinase 3 (AK3)	Arabidopsis thaliana	ATP	—	0.56	—	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 3 (AK3), ATP
aspartate kinase 3 (AK3)	Arabidopsis thaliana	L-aspartate	8.4	1.095	7.7 calc.	pH 8, 30 °C	PMID 17140415	Open record: aspartate kinase 3 (AK3), L-aspartate
aspartate kinase chimera BT (B. subtilis AK II / Thermus flavus AK)chimera BT	—	aspartate	—	10.6	1.45	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase chimera BT (B. subtilis AK II / Thermus flavus AK) chimera BT, aspartate
aspartate kinase chimera BT (B. subtilis AK II / Thermus flavus AK)chimera BT	—	ATP	15.25	6.9	2.2	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase chimera BT (B. subtilis AK II / Thermus flavus AK) chimera BT, ATP
aspartate kinase chimera BTT (B. subtilis AK II / Thermus flavus AK)chimera BTT	—	aspartate	—	3.9	3.07	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase chimera BTT (B. subtilis AK II / Thermus flavus AK) chimera BTT, aspartate
aspartate kinase chimera BTT (B. subtilis AK II / Thermus flavus AK)chimera BTT	—	ATP	11.87	4.5	2.62	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase chimera BTT (B. subtilis AK II / Thermus flavus AK) chimera BTT, ATP
aspartate kinase I	Escherichia coli	aspartate	—	0.97	—	pH 7.5, 37 °C	PMID 11368768	Open record: aspartate kinase I, aspartate
aspartate kinase I	Escherichia coli	ATP	—	0.98	—	pH 7.5, 37 °C	PMID 11368768	Open record: aspartate kinase I, ATP
aspartate kinase II (AK II, BBB)	Bacillus subtilis	aspartate	—	10	1.58	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase II (AK II, BBB), aspartate
aspartate kinase II (AK II, BBB)	Bacillus subtilis	ATP	15.87	6.5	2.45	pH 7.5, 30 °C	PMID 15033471	Open record: aspartate kinase II (AK II, BBB), ATP
aspartate kinase III	Escherichia coli	(L)-aspartate	13.2	7.9	1.678	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III, (L)-aspartate
aspartate kinase III	Escherichia coli	aspartate	—	0.32	—	pH 7.5, 37 °C	PMID 11368768	Open record: aspartate kinase III, aspartate
aspartate kinase III	Escherichia coli	ATP	—	0.22	—	pH 7.5, 37 °C	PMID 11368768	Open record: aspartate kinase III, ATP
aspartate kinase IIIvariant E119A	Escherichia coli	(L)-malate	2.5	10.5	0.24	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119A, (L)-malate
aspartate kinase IIIvariant E119C	Escherichia coli	(L)-malate	4.4	19.2	0.23	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119C, (L)-malate
aspartate kinase IIIvariant E119G	Escherichia coli	(L)-aspartate	0.1	32.3	0.003	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119G, (L)-aspartate
aspartate kinase IIIvariant E119G	Escherichia coli	(L)-malate	1.4	10.9	0.14	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119G, (L)-malate
aspartate kinase IIIvariant E119N	Escherichia coli	(L)-malate	0.1	43	0.003	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119N, (L)-malate
aspartate kinase IIIvariant E119P	Escherichia coli	(L)-malate	0.6	18.5	0.04	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119P, (L)-malate
aspartate kinase IIIvariant E119Q	Escherichia coli	(L)-malate	0.03	38.5	0.001	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119Q, (L)-malate
aspartate kinase IIIvariant E119S	Escherichia coli	(L)-aspartate	1.1	491.7	0.002	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119S, (L)-aspartate
aspartate kinase IIIvariant E119S	Escherichia coli	(L)-malate	2.2	12.7	0.17	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119S, (L)-malate
aspartate kinase IIIvariant E119T	Escherichia coli	(L)-malate	0.4	12.3	0.03	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119T, (L)-malate
aspartate kinase IIIvariant E119V	Escherichia coli	(L)-malate	0.4	23	0.02	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant E119V, (L)-malate
aspartate kinase IIIvariant V115A/E119S/E434V	Escherichia coli	(L)-aspartate	1.14	119.5	0.01	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant V115A/E119S/E434V, (L)-aspartate
aspartate kinase IIIvariant V115A/E119S/E434V	Escherichia coli	(L)-malate	6.8	8.3	0.82	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III variant V115A/E119S/E434V, (L)-malate
aspartate kinase III (Ec-LysC)variant V115A/E119S/E434V	Escherichia coli	L-malate	—	—	0.82	pH 7.5, 37 °C	PMID 28631755	Open record: aspartate kinase III (Ec-LysC) variant V115A/E119S/E434V, L-malate
aspartate kinase, monofunctional (GmAK)	Glycine max	ATP	—	0.68	3.38	pH 8, 25 °C	PMID 19897476	Open record: aspartate kinase, monofunctional (GmAK), ATP
aspartate kinase, monofunctional (GmAK)	Glycine max	L-aspartate	2.3	12.1	0.19	pH 8, 25 °C	PMID 19897476	Open record: aspartate kinase, monofunctional (GmAK), L-aspartate
aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I)	Arabidopsis thaliana	aspartatecosubstrate ATP	5	—	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I), aspartate
aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I)	Arabidopsis thaliana	aspartatewithout Ala; cosubstrate ATP (20 mM)	—	2.6	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I), aspartate
aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I)	Arabidopsis thaliana	aspartatewith 10 mM Ala (saturating activator)	—	2.3	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I), aspartate
aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I)	Arabidopsis thaliana	ATP	—	6.5	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform I (AK-HSDH I), aspartate kinase activity (AK I), ATP
aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II)	Arabidopsis thaliana	aspartatecosubstrate ATP	6.2	—	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II), aspartate
aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II)	Arabidopsis thaliana	aspartatewithout Ala; cosubstrate ATP (20 mM)	—	6.15	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II), aspartate
aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II)	Arabidopsis thaliana	aspartatewith 10 mM Ala (saturating activator)	—	1.5	—	pH 8, 30 °C	PMID 16216875	Open record: aspartate kinase-homoserine dehydrogenase isoform II (AK-HSDH II), aspartate kinase activity (AK II), aspartate
aspartokinase III (AK III)	Escherichia coli	aspartate	98	0.51	190		PMID 11888289	Open record: aspartokinase III (AK III), aspartate
aspartokinase III (AKIII)	Escherichia coli	ATP	—	0.2	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII), ATP
aspartokinase III (AKIII)	Escherichia coli	L-aspartate	—	0.69	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII), L-aspartate
aspartokinase III (AKIII)variant D202E	Escherichia coli	ATP	—	0.52	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant D202E, ATP
aspartokinase III (AKIII)variant D202E	Escherichia coli	L-aspartate	—	29	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant D202E, L-aspartate
aspartokinase III (AKIII)variant E119D	Escherichia coli	ATP	—	2.3	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant E119D, ATP
aspartokinase III (AKIII)variant E119D	Escherichia coli	L-aspartate	—	2152	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant E119D, L-aspartate
aspartokinase III (AKIII)variant K8R	Escherichia coli	ATP	—	0.36	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant K8R, ATP
aspartokinase III (AKIII)variant K8R	Escherichia coli	L-aspartate	—	26	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant K8R, L-aspartate
aspartokinase III (AKIII)variant R198K	Escherichia coli	ATP	—	3.9	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant R198K, ATP
aspartokinase III (AKIII)variant R198K	Escherichia coli	L-aspartate	—	114	—	pH 7.2, 25 °C	PMID 14623187	Open record: aspartokinase III (AKIII) variant R198K, L-aspartate
aspartokinase-homoserine dehydrogenase I (AK-HDH I)	Escherichia coli	aspartate	0.39	0.63	0.63		PMID 11888289	Open record: aspartokinase-homoserine dehydrogenase I (AK-HDH I), aspartate
aspartokinase-homoserine dehydrogenase I (AK-HDH I)	Escherichia coli	homoserine	0.24	1.2	0.21		PMID 11888289	Open record: aspartokinase-homoserine dehydrogenase I (AK-HDH I), homoserine
aspartokinase-homoserine dehydrogenase I (AK-HDH I)AK I domain (thrA1)	Escherichia coli	aspartate	6.3	0.47	14		PMID 11888289	Open record: aspartokinase-homoserine dehydrogenase I (AK-HDH I) AK I domain (thrA1), aspartate
aspartokinase-homoserine dehydrogenase I (AK-HDH I)HDH I domain (thrA2)	Escherichia coli	homoserine	0.51	17.2	0.03		PMID 11888289	Open record: aspartokinase-homoserine dehydrogenase I (AK-HDH I) HDH I domain (thrA2), homoserine
aspartokinase-homoserine dehydrogenase I (AK-HDH I)HDH I+ domain (thrA2+)	Escherichia coli	homoserine	3.3	0.68	4.9		PMID 11888289	Open record: aspartokinase-homoserine dehydrogenase I (AK-HDH I) HDH I+ domain (thrA2+), homoserine
bifunctional aspartate kinase-homoserine dehydrogenase 1 (GmAK-HSD-1), AK activity	Glycine max	ATP	—	0.894	0.393	pH 8, 25 °C	PMID 19897476	Open record: bifunctional aspartate kinase-homoserine dehydrogenase 1 (GmAK-HSD-1), AK activity, ATP
bifunctional aspartate kinase-homoserine dehydrogenase 1 (GmAK-HSD-1), AK activity	Glycine max	L-aspartate	0.352	5.26	0.0669	pH 8, 25 °C	PMID 19897476	Open record: bifunctional aspartate kinase-homoserine dehydrogenase 1 (GmAK-HSD-1), AK activity, L-aspartate
bifunctional aspartate kinase-homoserine dehydrogenase 2 (GmAK-HSD-2), AK activity	Glycine max	ATP	—	0.647	0.894	pH 8, 25 °C	PMID 19897476	Open record: bifunctional aspartate kinase-homoserine dehydrogenase 2 (GmAK-HSD-2), AK activity, ATP
bifunctional aspartate kinase-homoserine dehydrogenase 2 (GmAK-HSD-2), AK activity	Glycine max	L-aspartate	0.578	6.33	0.0914	pH 8, 25 °C	PMID 19897476	Open record: bifunctional aspartate kinase-homoserine dehydrogenase 2 (GmAK-HSD-2), AK activity, L-aspartate