EC 3.4.24.15: thimet oligopeptidase

HydrolasesOpen in Browse

CatLog read 223 records for EC 3.4.24.15 from 7 papers, for 1 organism. Names in these papers: thimet oligopeptidase (TOP), thimet oligopeptidase (EP24.15), endopeptidase 24.15.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 1 record for EC 3.4.24.15 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.24.15 in Browse.

Papers

Papers with records for EC 3.4.24.15
Paper	Organisms	Records
Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin	Rattus norvegicus	74
The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor binding	—	44
Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection	Rattus norvegicus	34
Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase	Rattus norvegicus	25
Catalytic properties of thimet oligopeptidase H600A mutant	—	20
Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11)	Rattus norvegicus	14
Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides	Rattus norvegicus	12

Records

Records for EC 3.4.24.15 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
endopeptidase 24.15	Rattus norvegicus	beta-neoendorphin, Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro	37.9	—	998	pH 7	PMID 2803255	Open record: endopeptidase 24.15, beta-neoendorphin, Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro
endopeptidase 24.15	Rattus norvegicus	bradykinin, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg	33.8	—	500	pH 7	PMID 2803255	Open record: endopeptidase 24.15, bradykinin, Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
endopeptidase 24.15	Rattus norvegicus	dynorphin A(1-8), Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile	86.4	—	1.4 × 10³	pH 7	PMID 2803255	Open record: endopeptidase 24.15, dynorphin A(1-8), Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile
endopeptidase 24.15	Rattus norvegicus	luteinizing hormone-releasing hormone, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2	12	—	126	pH 7	PMID 2803255	Open record: endopeptidase 24.15, luteinizing hormone-releasing hormone, pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Ala-Ala-Gly-p-aminobenzoate	5.3	3.45	1.5		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Ala-Ala-Gly-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Ala-Ala-Leu-p-aminobenzoate	17	1.54	11		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Ala-Ala-Leu-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Ala-Ala-Phe-p-aminobenzoate	48.3	0.83	58		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Ala-Ala-Phe-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Gly-Ala-Phe-p-aminobenzoate	4.54	1.36	3.3		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Gly-Ala-Phe-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Phe-Ala-Ala-Phe-p-aminobenzoate	179	0.058	3.1 × 10³		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Phe-Ala-Ala-Phe-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-benzoyl-Gly-Phe-Ala-Phe-p-aminobenzoate	19.2	0.39	49		PMID 2803255	Open record: endopeptidase 24.15, N-benzoyl-Gly-Phe-Ala-Phe-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	N-tert-butoxycarbonyl-Phe-Ala-Ala-Phe-p-aminobenzoate	94.1	0.1	940		PMID 2803255	Open record: endopeptidase 24.15, N-tert-butoxycarbonyl-Phe-Ala-Ala-Phe-p-aminobenzoate
endopeptidase 24.15	Rattus norvegicus	neurotensin, pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu	7.9	—	210	pH 7	PMID 2803255	Open record: endopeptidase 24.15, neurotensin, pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu
thimet oligopeptidase (EP24.15)	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.3	5.7 × 10⁻⁵	5.9 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15), (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.44	0.00788	50	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15), 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)	Rattus norvegicus	Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH	11.2	0.024	470	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15), Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH
thimet oligopeptidase (EP24.15)	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.33	0.0012	280	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15), Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G599A	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.86	1.29 × 10⁻⁴	6.7 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G599A, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G599A	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.03	0.00408	7	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G599A, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G599A	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.18	0.0025	70	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G599A, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G603A	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.28	5.4 × 10⁻⁵	5.2 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G603A	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	2.32	0.00401	580	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G603A	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	1.26	0.0029	430	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G603A/G604A	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.27	4.1 × 10⁻⁵	6.59 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A/G604A, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G603A/G604A	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	2.44	0.00543	450	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A/G604A, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G603A/G604A	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	1.22	0.0057	210	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603A/G604A, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G603P	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.18	0.0021	90	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603P, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G603P	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.0026	0.00643	0.41	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603P, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G603P	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.00449	0.0029	1.6	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G603P, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G604A	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.53	9 × 10⁻⁵	5.8 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G604A, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G604A	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.11	0.00825	13	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G604A, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G604A	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.11	0.0026	40	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G604A, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant G611A	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	1.34	1.36 × 10⁻⁴	9.8 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G611A, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant G611A	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.193	0.0067	29	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G611A, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant G611A	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.3	0.005	60	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant G611A, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant Y605F	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.34	8 × 10⁻⁵	4.4 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant Y605F	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.0086	0.0082	1.1	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant Y605F	Rattus norvegicus	Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH	1.4	0.037	38	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F, Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH
thimet oligopeptidase (EP24.15)variant Y605F	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.012	0.0042	2.9	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant Y605F/Y612F	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.1	5.1 × 10⁻⁴	200	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F/Y612F, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant Y605F/Y612F	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	0.0023	0.0081	0.28	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F/Y612F, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant Y605F/Y612F	Rattus norvegicus	Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH	0.025	0.014	1.7	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F/Y612F, Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH
thimet oligopeptidase (EP24.15)variant Y605F/Y612F	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	0.0015	0.0031	0.47	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y605F/Y612F, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (EP24.15)variant Y612F	Rattus norvegicus	(7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin	0.75	5.7 × 10⁻⁴	1.3 × 10³	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y612F, (7-methoxycoumarin-4-acetyl)-[Ala7, Lys(dinitrophenol)9]-bradykinin
thimet oligopeptidase (EP24.15)variant Y612F	Rattus norvegicus	7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol	3.7 × 10⁻⁴	0.009	0.041	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y612F, 7-methoxycoumarin-4-acetyl-Pro-Leu-Gly-Pro-Lys-dinitrophenol
thimet oligopeptidase (EP24.15)variant Y612F	Rattus norvegicus	Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH	0.061	0.034	1.8	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y612F, Mca-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-OH
thimet oligopeptidase (EP24.15)variant Y612F	Rattus norvegicus	Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)	5.2 × 10⁻⁴	0.0026	0.2	pH 7.8, 23 °C	PMID 18959747	Open record: thimet oligopeptidase (EP24.15) variant Y612F, Mca-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Lys(Dnp)-OH (modified neurotensin)
thimet oligopeptidase (TOP)	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.7	8 × 10⁻⁴	3375	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	—	o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6.2	9 × 10⁻⁴	6889	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10.6	5 × 10⁻⁴	2.12 × 10⁴	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	9.8	7 × 10⁻⁴	1.4 × 10⁴	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.3	0.0034	677	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10.6	9 × 10⁻⁴	11,778	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.8	0.0027	1407	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.7	8 × 10⁻⁴	3375	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.5	0.0013	3462	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	12.1	0.0013	9308	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.8	0.0019	2 × 10³	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant A607G	—	o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.9	8 × 10⁻⁴	6125	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant A607G, o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	11.1	0.0143	1.6 × 10³		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	9.1	0.0109	839		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Asp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.3	9 × 10⁻⁴	333		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Asp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	7	0.0091	771		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.6	0.0011	1417		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	13.3	0.0321	414		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.19	0.112	2		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.9	0.0105	561		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ala-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.7	0.0218	78		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ala-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.5	0.0213	211		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Asp-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.03	0.0075	8		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Asp-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.7	0.0148	47		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Glu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.01	0.0192	1		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Glu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-His-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.3	0.0131	20.6		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-His-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.04	0.0062	10		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Leu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.02	0.0122	8		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Leu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.9	0.0093	317		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.4	0.0135	30		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Pro-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	9.2	0.0127	724		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant H600A	—	ortho-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6	0.0208	288		PMID 20226173	Open record: thimet oligopeptidase (TOP) variant H600A, ortho-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10.4	0.0098	1061	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineoverall hydrolysis at both cleaved bonds (X–Phe and Phe–Ser)	—	0.01	100	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the X–Phe bond only	0.6	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the Phe–Ser bond only	0.4	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.8	0.0058	1 × 10³	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.3	0.003	1767	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.8	0.0096	188	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5	0.005	1 × 10³	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineoverall hydrolysis at both cleaved bonds (X–Phe and Phe–Ser)	—	0.0102	1745	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the X–Phe bond only	7	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the Phe–Ser bond only	10.8	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	12.7	0.016	794	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineoverall hydrolysis at both cleaved bonds (X–Phe and Phe–Ser)	—	0.0043	1372	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the X–Phe bond only	4.7	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the Phe–Ser bond only	1.2	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.5	0.02	75	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamineoverall hydrolysis at both cleaved bonds (X–Phe and Phe–Ser)	—	0.0074	122	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the X–Phe bond only	0.2	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediaminecleavage at the Phe–Ser bond only	0.7	—	—	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605A	—	o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	20.4	0.011	1855	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605A, o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.6	0.0047	553	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.5	0.0044	341	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	12.1	0.0054	2241	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.2	0.0021	1524	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	15.1	0.0086	1756	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	13.6	0.0014	9714	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Ile-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	13.6	0.0023	5913	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	27.3	0.0033	8273	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.4	0.0015	933	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.7	0.0047	362	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	9.1	0.0015	6067	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Trp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)variant Y605F	—	o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6.4	0.0023	2783	pH 7.4, 37 °C	PMID 17313369	Open record: thimet oligopeptidase (TOP) variant Y605F, o-aminobenzoyl-Gly-Phe-Ser-Tyr-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Ala-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0045	2.8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Ala-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Arg-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.3	0.0015	2.8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Arg-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Asn-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	7.8 × 10⁻⁴	4.8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Asn-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Asp-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.003	1.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Asp-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gln-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0015	3.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gln-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Glu-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0012	1.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Glu-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Ala-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.5	0.0042	600	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Ala-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Arg-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	13.3	0.0036	3.7 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Arg-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Asn-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.2	0.0045	1.2 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Asn-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Asp-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.2	0.0166	100	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Asp-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Gln-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.9	0.0099	300	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Gln-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Glu-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.8	0.0225	300	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Glu-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-His-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	14.5	0.0048	3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-His-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Ile-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	8.4	0.0028	3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Ile-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Leu-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	11.5	0.0037	3.1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Leu-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ala-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.7	7.1 × 10⁻⁴	8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ala-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Arg-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	7.7	0.0053	1.5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Arg-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Asn-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.5	2.7 × 10⁻⁴	9.3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Asn-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Asp-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.4	0.0068	500	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Asp-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Gln-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.8	0.0149	100	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Gln-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Glu-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4	0.0052	800	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Glu-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-His-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.89	7.2 × 10⁻⁴	1.2 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-His-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ile-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.9	9.9 × 10⁻⁴	5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ile-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Leu-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3	3.8 × 10⁻⁴	7.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Leu-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Phe-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.3	0.0014	3.8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Phe-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Pro-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.6	0.006	300	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Pro-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10.2	0.0012	8.5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Ala-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	7	0.0011	6.4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Arg-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Asn-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	8.9	0.0016	5.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Asn-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Asp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.7	0.0038	200	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Asp-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6.3	0.0012	5.3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Gln-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.5	0.0075	200	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Glu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	24.7	0.0076	3.3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-His-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.4	0.0016	2.1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Leu-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6.7	6.9 × 10⁻⁴	9.7 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Phe-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Ala-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	18.5	0.004	4.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Ala-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.7	0.0018	1.5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Asn-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10.1	0.005	2 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Asn-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Asp-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.037	500	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Asp-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	12.3	0.0043	2.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Gln-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Glu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.018	200	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Glu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-His-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.3	0.0015	3.5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-His-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0085	1.1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Ile-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Leu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0045	1.1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Leu-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine	2.3	0.002	1.2 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine	17.5	0.0048	3.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ala-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine	0.77	1.9 × 10⁻⁴	4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Arg-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine	12.3	0.0018	6.8 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Asn-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6.3	0.0022	2.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Glu-N-(2,4-dinitrophenyl)ethylenediamine	3.1	0.0012	2.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Glu-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine	3	5 × 10⁻⁴	6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ile-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Leu-N-(2,4-dinitrophenyl)ethylenediamine	4.8	5.7 × 10⁻⁴	8.4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Leu-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine	7.1	6.9 × 10⁻⁴	1 × 10⁴	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Phe-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Pro-N-(2,4-dinitrophenyl)ethylenediamine	2.6	0.0059	400	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Pro-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine	4.3	0.0043	1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Arg-Ser-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Asn-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.131	90	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Asn-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4	0.0139	300	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0038	800	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Gln-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.119	100	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-His-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0126	400	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-His-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine	11.1	0.0017	6.5 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.1	0.0044	700	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.1	0.0019	600	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0203	400	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.007	400	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Phe-Ser-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Pro-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	21.5	0.0073	2.9 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Pro-Ser-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	8.8	0.0037	2.4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Phe-Ser-Ser-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Pro-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	11.5	0.0037	3.1 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Pro-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Gly-Ser-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.2	0.006	500	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Gly-Ser-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-His-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	6	0.0017	3.4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-His-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Ile-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	1.6 × 10⁻⁴	1.5 × 10⁴	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Ile-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Leu-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	8.2 × 10⁻⁴	7.3 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Leu-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Phe-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.6	0.001	1.6 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Phe-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	o-aminobenzoyl-Ser-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0014	3.4 × 10³	pH 7.4, 37 °C	PMID 11284698	Open record: thimet oligopeptidase (TOP), o-aminobenzoyl-Ser-Phe-Ser-Pro-Phe-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Ala-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.75	0.0102	74	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Ala-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Ala-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.6	0.0071	507	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Ala-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Lys-Ala-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	8	0.064	125	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Lys-Ala-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Lys-Pro-Ala-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	4.2	0.036	117	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Lys-Pro-Ala-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Ala-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	8.7	0.015	580	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Ala-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine	5.7	0.0124	460	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.7	0.0121	58	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.2	0.021	152	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Gln-N-(2,4-dinitrophenyl)ethylenediamine	1.1	—	—	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.9	—	—	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 1	15	0.0048	3.1 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine0 M NaCl; Table 4	—	—	2.6 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 4	—	—	3.4 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.5 M NaCl; Table 4	—	—	8 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ala-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine	11	0.0015	7.3 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Arg-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asn-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0018	3.9 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asn-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 1	—	0.0032	1.6 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine0 M NaCl; Table 4	—	—	2.8 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 4	—	—	1.7 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.5 M NaCl; Table 4	—	—	900	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Asp-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0015	1.9 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Glu-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-His-Gln-N-(2,4-dinitrophenyl)ethylenediamine	10	0.0014	7.1 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-His-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 1	—	0.002	2.5 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine0 M NaCl; Table 4	—	—	2.1 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 4	—	—	2.7 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.5 M NaCl; Table 4	—	—	6.1 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine	—	0.0025	2.1 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine	15	0.0036	4.2 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Phe-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	7.4	0.0022	3.4 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Tyr-Gln-N-(2,4-dinitrophenyl)ethylenediamine	19	0.0043	4.4 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Tyr-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 1	—	0.0017	2.6 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine0 M NaCl; Table 4	—	—	1.4 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.1 M NaCl; Table 4	—	—	1.8 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine0.5 M NaCl; Table 4	—	—	3.7 × 10³	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-N-(2,4-dinitrophenyl)ethylenediamine	0.7	0.0017	400	pH 7.4, 37 °C	PMID 12199711	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Arg-Arg-Val-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.7	0.0028	1321	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Gly-Gly-Phe-Leu-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.3	0.007	43	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine	0.3	—	—	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-Gln-N-(2,4-dinitrophenyl)ethylenediamine
thimet oligopeptidase (TOP)	Rattus norvegicus	ortho-aminobenzoyl-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine	3.7	0.114	32	pH 7.4, 37 °C	PMID 11355859	Open record: thimet oligopeptidase (TOP), ortho-aminobenzoyl-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine