EC 6.2.1.13: acetate-CoA ligase (ADP-forming)

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CatLog read 148 records for EC 6.2.1.13 from 7 papers, for 5 organisms. Names in these papers: ADP-forming acetyl-CoA synthetase (EhACD), ADP-forming acetyl-CoA synthetase (ACD), acetyl-CoA synthetase (ADP-dependent) ACS II, acetyl-CoA synthetase (ADP-forming) (ACS) and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 50 records for EC 6.2.1.13 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.2.1.13 in Browse.

Papers

Papers with records for EC 6.2.1.13
Paper	Organisms	Records
Investigating the mechanism of ADP-forming acetyl-CoA synthetase from the protozoan parasite Entamoeba histolytica	Entamoeba histolytica	60
Purification and characterization of two reversible and ADP-dependent acetyl coenzyme A synthetases from the hyperthermophilic archaeon Pyrococcus furiosus	Pyrococcus furiosus	23
Biochemical and kinetic characterization of the recombinant ADP-forming acetyl coenzyme A synthetase from the amitochondriate protozoan Entamoeba histolytica	Entamoeba histolytica	17
Novel type of ADP-forming acetyl coenzyme A synthetase in hyperthermophilic archaea: heterologous expression and characterization of isoenzymes from the sulfate reducer Archaeoglobus fulgidus and…	Archaeoglobus fulgidus, Methanococcus jannaschii	16
Roles of acetyl-CoA synthetase (ADP-forming) and acetate kinase (PPi-forming) in ATP and PPi supply in Entamoeba histolytica	Entamoeba histolytica	12
Reaction mechanism and structural model of ADP-forming Acetyl-CoA synthetase from the hyperthermophilic archaeon Pyrococcus furiosus: evidence for a second active site histidine residue	Pyrococcus furiosus	11
Characterization of two members among the five ADP-forming acyl coenzyme A (Acyl-CoA) synthetases reveals the presence of a 2-(Imidazol-4-yl)acetyl-CoA synthetase in Thermococcus kodakarensis	Thermococcus kodakarensis	9

Records

Records for EC 6.2.1.13 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	acetate	65	1.1	60	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, acetate
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	acetyl coenzyme A	157	0.025	6.28 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, acetyl coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	ADP	203	0.15	1.35 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, ADP
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	ATP	82	0.477	170	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, ATP
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	coenzyme A	73	0.018	4.06 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	GDP	411	0.132	3.11 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, GDP
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	GTP	121	0.43	280	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, GTP
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	isobutyrate	55	0.457	120	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, isobutyrate
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	isobutyryl coenzyme A	121	0.029	4.17 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, isobutyryl coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS I	Pyrococcus furiosus	phosphate	182	0.396	460	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS I, phosphate
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	acetate	67	10.7	6	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, acetate
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	acetyl coenzyme A	42	0.026	1.62 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, acetyl coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	ADP	115	0.061	1.89 × 10³	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, ADP
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	ATP	68	0.326	210	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, ATP
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	coenzyme A	70	0.074	950	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	GDP	21	0.236	90	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, GDP
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	GTP	27	0.77	40	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, GTP
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	indoleacetate	66	2	30	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, indoleacetate
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	isobutyrate	22	5.8	4	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, isobutyrate
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	isobutyryl coenzyme A	8	0.012	670	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, isobutyryl coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	phenylacetate	89	0.768	120	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, phenylacetate
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	phenylacetyl coenzyme A	138	0.004	3.45 × 10⁴	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, phenylacetyl coenzyme A
acetyl-CoA synthetase (ADP-dependent) ACS II	Pyrococcus furiosus	phosphate	117	0.58	200	pH 8.4, 80 °C	PMID 8830684	Open record: acetyl-CoA synthetase (ADP-dependent) ACS II, phosphate
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	Acetate	35	1.3	26	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), Acetate
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	Acetate	46	0.8	58	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), Acetate
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	acetyl-coenzyme A	34	0.14	239	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), acetyl-coenzyme A
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	acetyl-coenzyme A	55	0.13	458	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), acetyl-coenzyme A
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	ADP	—	1.9	17	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), ADP
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	ADP	—	0.9	76	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), ADP
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	ATP	—	0.6	59	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), ATP
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	ATP	—	0.3	144	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), ATP
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	coenzyme A	—	0.4	90	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), coenzyme A
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	coenzyme A	—	0.2	213	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), coenzyme A
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	inorganic phosphate	—	2.7	12	pH 6, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), inorganic phosphate
acetyl-CoA synthetase (ADP-forming) (ACS)	Entamoeba histolytica	inorganic phosphate	—	1.8	32	pH 7, 37 °C	PMID 26922831	Open record: acetyl-CoA synthetase (ADP-forming) (ACS), inorganic phosphate
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	Acetate	138	0.34	400	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), Acetate
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	acetyl coenzyme A	95	0.01	9.2 × 10³	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), acetyl coenzyme A
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	adenosine 5'-diphosphate	70	0.007	1 × 10⁴	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), adenosine 5'-diphosphate
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	adenosine 5'-triphosphate	150	0.133	1.12 × 10³	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), adenosine 5'-triphosphate
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	coenzyme A	110	0.027	4 × 10³	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), coenzyme A
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	Phenylacetate	11.5	0.1	110	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), Phenylacetate
acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I)	Archaeoglobus fulgidus	phosphate	58	0.11	520	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1211 (ACD I), phosphate
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	Acetate	1.84	2.58	0.7	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), Acetate
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	adenosine 5'-triphosphate	3	0.03	100	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), adenosine 5'-triphosphate
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	coenzyme A	2.9	0.53	5.4	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), coenzyme A
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	Indole-3-acetate	3.45	1.24	2.7	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), Indole-3-acetate
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	Phenylacetate	3	2.5	1.2	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), Phenylacetate
acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II)	Archaeoglobus fulgidus	phenylacetyl coenzyme A	2.3	0.017	140	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-AF1938 (ACD II), phenylacetyl coenzyme A
acetyl-CoA synthetase (ADP-forming), ACD-MJ0590	Methanococcus jannaschii	acetyl coenzyme A	—	0.037	—	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-MJ0590, acetyl coenzyme A
acetyl-CoA synthetase (ADP-forming), ACD-MJ0590	Methanococcus jannaschii	adenosine 5'-diphosphate	—	0.015	—	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-MJ0590, adenosine 5'-diphosphate
acetyl-CoA synthetase (ADP-forming), ACD-MJ0590	Methanococcus jannaschii	phosphate	—	0.47	—	55 °C	PMID 11790732	Open record: acetyl-CoA synthetase (ADP-forming), ACD-MJ0590, phosphate
ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2)	Thermococcus kodakarensis	2-(imidazol-4-yl)acetate	37.8	—	—	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2), 2-(imidazol-4-yl)acetate
ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2)	Thermococcus kodakarensis	adenosine 5'-triphosphate	37.9	0.03	1.26 × 10³	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2), adenosine 5'-triphosphate
ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2)	Thermococcus kodakarensis	coenzyme A	39.6	0.0625	633	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming 2-(imidazol-4-yl)acetyl-CoA synthetase (ICSTk; TK2127/TK0943 alpha2beta2), coenzyme A
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	acetate	240	14	16	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), acetate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	acetyl coenzyme ADTNB (Ellman) assay of CoASH release; 50 mM Tris-HCl; pH 7.3	110	0.04	2.6 × 10³	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), acetyl coenzyme A
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	acetyl coenzyme A100 mM Tris-HCl pH 7.3; 5.5 mM glucose; 1 mM NADP+	130	0.017	7.6 × 10³ calc.	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), acetyl coenzyme A
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	adenosine 5'-diphosphateDTNB (Ellman) assay of CoASH release; 50 mM Tris-HCl; pH 7.3	140	1.6	89	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	adenosine 5'-diphosphateDTNB (Ellman) assay of CoASH release; 50 mM Tris-HCl; pH 7.3	24	0.71	34	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	adenosine 5'-diphosphate100 mM Tris-HCl pH 7.3; 5.5 mM glucose; 1 mM NADP+	140	0.94	150 calc.	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	adenosine 5'-triphosphateacetyl-CoA-forming direction; fixed 100 mM acetate; 1 mM CoA	320	12	27	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	adenosine 5'-triphosphatepropionyl-CoA-forming direction; fixed 250 mM propionate	240	7.2	33	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	coenzyme Aacetyl-CoA-forming direction; fixed 100 mM acetate	220	0.2	1.1 × 10³	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), coenzyme A
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	coenzyme Apropionyl-CoA-forming direction; fixed 250 mM propionate	260	1.6	160	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), coenzyme A
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	guanosine 5'-diphosphate	170	1.9	90	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), guanosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	guanosine 5'-triphosphate	180	10	18	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), guanosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	phosphateDTNB (Ellman) assay of CoASH release; 50 mM Tris-HCl; pH 7.3	120	1.8	65	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), phosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	phosphateDTNB (Ellman) assay of CoASH release; 50 mM Tris-HCl; pH 7.3	18	1.5	12	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), phosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	phosphate100 mM Tris-HCl pH 7.3; 5.5 mM glucose; 1 mM NADP+	180	2.1	86 calc.	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), phosphate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	propionate	190	29	6.3	pH 7.5, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), propionate
ADP-forming acetyl-CoA synthetase (ACD)	Entamoeba histolytica	propionyl coenzyme A	21	0.032	650	pH 7.3, 37 °C	PMID 25303954	Open record: ADP-forming acetyl-CoA synthetase (ACD), propionyl coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	acetate	2.9	1.3	2.3		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	acetyl-coenzyme A	2.5	0.008	207		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	adenosine 5'-diphosphate	2.9	0.39	6.8		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	adenosine 5'-triphosphate	3.2	4	0.81		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	coenzyme A	4.2	0.12	36		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674A	Entamoeba histolytica	phosphate (orthophosphate)	2.6	1.42	2		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674A, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	acetate	50	3.9	13		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	acetyl-coenzyme A	16	0.022	704		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	adenosine 5'-diphosphate	25	1.44	17		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	adenosine 5'-triphosphate	53	4.6	9.8		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	coenzyme A	44	0.24	224		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674E	Entamoeba histolytica	phosphate (orthophosphate)	25	2.8	8.9		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674E, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	acetate	1.3	0.96	1.3		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	acetyl-coenzyme A	1.3	0.016	78		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	adenosine 5'-diphosphate	1.2	0.43	2.8		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	adenosine 5'-triphosphate	1.2	2.8	0.44		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	coenzyme A	1.2	0.041	28		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant D674N	Entamoeba histolytica	phosphate (orthophosphate)	0.9	0.57	1.6		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant D674N, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	acetate	3.3	0.68	4.8		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	acetyl-coenzyme A	2.7	0.01	266		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	adenosine 5'-diphosphate	2.8	0.41	6.9		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	adenosine 5'-triphosphate	3.3	2.2	1.6		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	coenzyme A	4.2	0.07	60		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533A	Entamoeba histolytica	phosphate (orthophosphate)	2.3	0.75	3.1		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533A, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	acetate	0.18	0.31	0.59		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	acetyl-coenzyme A	1.6	0.027	60		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	adenosine 5'-diphosphate	1.7	0.6	2.9		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	adenosine 5'-triphosphate	0.25	1.2	0.21		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	coenzyme A	0.25	0.011	23		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533D	Entamoeba histolytica	phosphate (orthophosphate)	1.7	0.25	7.3		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533D, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	acetate	0.26	0.4	0.67		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	acetyl-coenzyme A	0.12	0.012	10		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	adenosine 5'-diphosphate	0.27	1.19	0.2		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	adenosine 5'-triphosphate	0.28	3.9	0.07		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	coenzyme A	0.27	0.26	1.1		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533E	Entamoeba histolytica	phosphate (orthophosphate)	0.22	0.18	1.3		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533E, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	acetate	3.4	0.84	4.1		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	acetyl-coenzyme A	2.4	0.03	79		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	adenosine 5'-diphosphate	3.3	0.97	3.4		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	adenosine 5'-triphosphate	3.7	1.7	2.4		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	coenzyme A	4.1	0.13	287		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533K	Entamoeba histolytica	phosphate (orthophosphate)	3.1	3.25	0.97		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533K, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	acetate	1.5	0.76	1.9		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	acetyl-coenzyme A	1.4	0.015	92		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	adenosine 5'-diphosphate	1.4	0.57	2.5		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	adenosine 5'-triphosphate	2	7.7	0.26		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	coenzyme A	2	0.08	26		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533N	Entamoeba histolytica	phosphate (orthophosphate)	1.5	0.94	1.7		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533N, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	acetate	1.2	0.55	2.2		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	acetyl-coenzyme A	1.7	0.019	90		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	adenosine 5'-diphosphate	2.5	1.28	1.9		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	adenosine 5'-triphosphate	1.4	2.5	116		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	coenzyme A	1.3	0.011	0.57		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533Q	Entamoeba histolytica	phosphate (orthophosphate)	1.8	0.86	2.1		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533Q, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	acetate	5.6	1.7	3.3		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, acetate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	acetyl-coenzyme A	18	0.016	1115		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, acetyl-coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	adenosine 5'-diphosphate	20	0.64	32		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	adenosine 5'-triphosphate	6.6	2.5	2.7		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	coenzyme A	7	0.1	70		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, coenzyme A
ADP-forming acetyl-CoA synthetase (EhACD)variant H533R	Entamoeba histolytica	phosphate (orthophosphate)	14	0.15	95		PMID 28129670	Open record: ADP-forming acetyl-CoA synthetase (EhACD) variant H533R, phosphate (orthophosphate)
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	2-methylpropanoate	50.9	—	—	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), 2-methylpropanoate
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	2-sulfanylacetate	26.1	—	—	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), 2-sulfanylacetate
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	acetate	49.3	—	—	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), acetate
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	adenosine 5'-triphosphate	53.7	0.0556	965	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	coenzyme A	53.1	0.0056	9.49 × 10³	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), coenzyme A
ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2)	Thermococcus kodakarensis	phenylacetate	40.6	—	—	pH 6.5, 55 °C	PMID 24163338	Open record: ADP-forming acetyl-CoA synthetase III (ACS IIITk; TK0944/TK0943 alpha2beta2), phenylacetate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant D212Eβ	Pyrococcus furiosus	acetate	—	0.794	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant D212Eβ, acetate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant D212Eβ	Pyrococcus furiosus	adenosine 5'-diphosphate	—	0.283	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant D212Eβ, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant D212Eβ	Pyrococcus furiosus	adenosine 5'-triphosphate	—	0.473	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant D212Eβ, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant D212Eβ	Pyrococcus furiosus	coenzyme A	—	0.041	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant D212Eβ, coenzyme A
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant D212Eβ	Pyrococcus furiosus	phosphate	—	0.714	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant D212Eβ, phosphate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	acetate	—	0.783	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, acetate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	acetyl coenzyme A	—	0.0062	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, acetyl coenzyme A
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	adenosine 5'-diphosphate	—	0.0741	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, adenosine 5'-diphosphate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	adenosine 5'-triphosphate	—	0.388	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, adenosine 5'-triphosphate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	coenzyme A	—	0.0771	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, coenzyme A
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)variant E218Dα	Pyrococcus furiosus	phosphate	—	0.919	—	pH 6.5, 55 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2) variant E218Dα, phosphate