EC 2.5.1.6: methionine adenosyltransferase

TransferasesOpen in Browse

CatLog read 151 records for EC 2.5.1.6 from 10 papers, for 6 organisms. Names in these papers: S-adenosylmethionine synthetase (AdoMet synthetase), S-adenosylmethionine synthetase (EcMAT), methionine adenosyltransferase (Mj-MAT), S-adenosylmethionine synthetase (MAT) and 4 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 86 records for EC 2.5.1.6 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.6 in Browse.

Papers

Papers with records for EC 2.5.1.6
Paper	Organisms	Records
The active site loop of S-adenosylmethionine synthetase modulates catalytic efficiency	Escherichia coli	31
Subunit association as the stabilizing determinant for archaeal methionine adenosyltransferases	Methanococcus jannaschii	30
The bifunctional active site of S-adenosylmethionine synthetase. Roles of the basic residues	Escherichia coli	21
S-Adenosylmethionine synthetase from Escherichia coli	Escherichia coli	14
Engineering of Methionine Adenosyltransferase Reveals Key Roles of Electrostatic Interactions in Enhanced Catalytic Activity	Bacteroides fragilis	13
Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling	Escherichia coli	10
Semi-rationally engineered variants of S-adenosylmethionine synthetase from Escherichia coli with reduced product inhibition and improved catalytic activity	Escherichia coli	10
Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus	Sulfolobus solfataricus	8
Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase	Plasmodium falciparum	8
Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes	Homo sapiens	6

Records

Records for EC 2.5.1.6 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
methionine adenosyltransferase (BfMAT)	Bacteroides fragilis	adenosine 5'-triphosphate	0.79	0.02821	28	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT), adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42C	Bacteroides fragilis	adenosine 5'-triphosphate	1.33	0.02998	44.36	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42C, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42C/E55L	Bacteroides fragilis	adenosine 5'-triphosphate	1.52	0.02744	55.39	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42C/E55L, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42C/E55L/K290I	Bacteroides fragilis	adenosine 5'-triphosphate	2.43	0.01111	218.7	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42C/E55L/K290I, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42M	Bacteroides fragilis	adenosine 5'-triphosphate	1.38	0.0317	43.53	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42M, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42M/E55L	Bacteroides fragilis	adenosine 5'-triphosphate	1.45	0.04368	33.2	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42M/E55L, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42M/E55L/K290I	Bacteroides fragilis	adenosine 5'-triphosphate	2.29	0.01936	118.3	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42M/E55L/K290I, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42R	Bacteroides fragilis	adenosine 5'-triphosphate	1.47	0.04841	30.37	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42R, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42R/E55L	Bacteroides fragilis	adenosine 5'-triphosphate	1.48	0.02327	63.6	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42R/E55L, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E42R/E55L/K290I	Bacteroides fragilis	adenosine 5'-triphosphate	2.26	0.04303	52.52	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E42R/E55L/K290I, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E55L	Bacteroides fragilis	adenosine 5'-triphosphate	1.22	0.0439	27.79	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E55L, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant E55L/K290I	Bacteroides fragilis	adenosine 5'-triphosphate	1.6	0.02729	58.63	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant E55L/K290I, adenosine 5'-triphosphate
methionine adenosyltransferase (BfMAT)variant K290I	Bacteroides fragilis	adenosine 5'-triphosphate	1.51	0.04717	32.01	pH 8, 37 °C	PMID 37642924	Open record: methionine adenosyltransferase (BfMAT) variant K290I, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.19	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT), adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)	Methanococcus jannaschii	L-methionine	1.46	0.31	4.7 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT), L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.11	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F	Methanococcus jannaschii	L-methionine	1.85	0.31	6.0 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y120W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.13	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y120W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y120W	Methanococcus jannaschii	L-methionine	3.31	0.54	6.1 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y120W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y170W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.1	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y170W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y170W	Methanococcus jannaschii	L-methionine	2.39	1	2.4 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y170W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y226W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.1	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y226W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y226W	Methanococcus jannaschii	L-methionine	5.08	0.3	17 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y226W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y233W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.2	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y233W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y233W	Methanococcus jannaschii	L-methionine	7.24	0.47	15 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y233W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y255W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.19	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y255W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y255W	Methanococcus jannaschii	L-methionine	2.39	0.5	4.8 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y255W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y267W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.2	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y267W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y267W	Methanococcus jannaschii	L-methionine	2.31	0.45	5.1 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y267W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y273W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.24	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y273W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y273W	Methanococcus jannaschii	L-methionine	1.54	0.3	5.1 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y273W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y323W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.22	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y323W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y323W	Methanococcus jannaschii	L-methionine	1.62	0.13	12 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y323W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y344W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.22	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y344W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y344W	Methanococcus jannaschii	L-methionine	2.85	0.33	8.6 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y344W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y371W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.11	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y371W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y371W	Methanococcus jannaschii	L-methionine	4	0.25	16 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y371W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y49W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.18	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y49W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y49W	Methanococcus jannaschii	L-methionine	1	0.66	1.5 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y49W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y72W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.11	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y72W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y72W	Methanococcus jannaschii	L-methionine	1.62	0.13	12 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y72W, L-methionine
methionine adenosyltransferase (Mj-MAT)variant W387F/Y85W	Methanococcus jannaschii	adenosine 5'-triphosphate	—	0.21	—	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y85W, adenosine 5'-triphosphate
methionine adenosyltransferase (Mj-MAT)variant W387F/Y85W	Methanococcus jannaschii	L-methionine	2.77	0.57	4.9 calc.	55 °C	PMID 19348969	Open record: methionine adenosyltransferase (Mj-MAT) variant W387F/Y85W, L-methionine
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	adenosine 5'-triphosphateL-methionine; cosubstrate L-methionine	0.0328	0.0686	0.48	pH 8, 37 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), adenosine 5'-triphosphate
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	adenosine 5'-triphosphateL-ethionine; cosubstrate L-ethionine	0.0413	0.0969	0.43	pH 8, 37 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), adenosine 5'-triphosphate
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	adenosine 5'-triphosphateL-methionine; cosubstrate L-methionine	0.04677	0.0145	3.23	pH 8, 65 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), adenosine 5'-triphosphate
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	adenosine 5'-triphosphateL-ethionine; cosubstrate L-ethionine	0.0517	0.0592	0.87	pH 8, 65 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), adenosine 5'-triphosphate
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	L-ethionine	0.039	0.0056	6.95	pH 8, 37 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), L-ethionine
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	L-ethionine	0.0498	0.007	7.12	pH 8, 65 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), L-ethionine
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	L-methionine	0.0343	0.0023	14.92	pH 8, 37 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), L-methionine
methionine adenosyltransferase (sMAT)	Sulfolobus solfataricus	L-methionine	0.0487	0.0028	17.37	pH 8, 65 °C	PMID 24649856	Open record: methionine adenosyltransferase (sMAT), L-methionine
methionine adenosyltransferase II-α (hMAT2A)	Homo sapiens	(S)-(−)-methioninol	0.18	2.4	0.08	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A), (S)-(−)-methioninol
methionine adenosyltransferase II-α (hMAT2A)	Homo sapiens	L-methionine	0.43	0.14	3.2	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A), L-methionine
methionine adenosyltransferase II-α (hMAT2A)variant K289L	Homo sapiens	(S)-(−)-methioninol	0.068	1	0.068	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A) variant K289L, (S)-(−)-methioninol
methionine adenosyltransferase II-α (hMAT2A)variant K289L	Homo sapiens	L-methionine	0.013	0.78	0.018	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A) variant K289L, L-methionine
methionine adenosyltransferase II-α (hMAT2A)variant Q113D	Homo sapiens	(S)-(−)-methioninol	0.055	0.39	0.143	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A) variant Q113D, (S)-(−)-methioninol
methionine adenosyltransferase II-α (hMAT2A)variant Q113D	Homo sapiens	L-methionine	0.02	0.047	0.4	pH 8, 37 °C	PMID 32091873	Open record: methionine adenosyltransferase II-α (hMAT2A) variant Q113D, L-methionine
PfalMAT (methionine adenosyltransferase)	Plasmodium falciparum	ATP	—	0.56	1.9	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase), ATP
PfalMAT (methionine adenosyltransferase)	Plasmodium falciparum	L-methionine	1.06	0.034	31.2	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase), L-methionine
PfalMAT (methionine adenosyltransferase)variant C113S	Plasmodium falciparum	ATP	—	0.206	7.2	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C113S, ATP
PfalMAT (methionine adenosyltransferase)variant C113S	Plasmodium falciparum	L-methionine	1.48	0.051	32.2	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C113S, L-methionine
PfalMAT (methionine adenosyltransferase)variant C187S	Plasmodium falciparum	ATP	—	0.176	5.9	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C187S, ATP
PfalMAT (methionine adenosyltransferase)variant C187S	Plasmodium falciparum	L-methionine	1.05	0.043	24.5	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C187S, L-methionine
PfalMAT (methionine adenosyltransferase)variant C52S	Plasmodium falciparum	ATP	—	0.68	1.5	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C52S, ATP
PfalMAT (methionine adenosyltransferase)variant C52S	Plasmodium falciparum	L-methionine	1.02	0.046	22.3	pH 8.4, 37 °C	PMID 27466371	Open record: PfalMAT (methionine adenosyltransferase) variant C52S, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	(Rp)-adenosine 5'-O-(2-thiotriphosphate)Mn2+ as activating	—	0.4	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), (Rp)-adenosine 5'-O-(2-thiotriphosphate)
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	(Rp)-adenosine 5'-O-(2-thiotriphosphate)Co2+ as activating	—	0.2	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), (Rp)-adenosine 5'-O-(2-thiotriphosphate)
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	(Sp)-adenosine 5'-O-(2-thiotriphosphate)	—	0.05	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), (Sp)-adenosine 5'-O-(2-thiotriphosphate)
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	(Sp)-adenosine 5'-O-(2-thiotriphosphate)Mn2+ as activating	—	0.1	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), (Sp)-adenosine 5'-O-(2-thiotriphosphate)
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	(Sp)-adenosine 5'-O-(2-thiotriphosphate)Co2+ as activating	—	0.3	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), (Sp)-adenosine 5'-O-(2-thiotriphosphate)
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	3-deazaadenosine 5'-triphosphate	—	0.29	—	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), 3-deazaadenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	5'-mercapto-5'-deoxy-ATP0.1 M KCl	—	0.6	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), 5'-mercapto-5'-deoxy-ATP
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	5'-mercapto-5'-deoxy-ATP	—	0.6	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), 5'-mercapto-5'-deoxy-ATP
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	5′-amino-5′-deoxyadenosine triphosphate	0.03	0.14	0.21 calc.		PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), 5′-amino-5′-deoxyadenosine triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	adenosine 5'-triphosphateAdoMet synthetase reaction; cosubstrate L-methionine	—	0.1	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	adenosine 5'-triphosphateAdoMet synthetase reaction; L-methionine cosubstrate	—	0.04	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	adenosine 5'-triphosphateAdoMet synthetase reaction; L-methionine cosubstrate	—	0.4	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	adenosine 5'-triphosphate	—	0.13	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	adenosine 5'-triphosphateAdoMet synthetase reaction with selenomethionine; 5 mM MgCl2	—	0.15	—		PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	L-methionine	—	0.1	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)	Escherichia coli	triphosphate	—	0.06	—	pH 8.3, 25 °C	PMID 6251075	Open record: S-adenosylmethionine synthetase (AdoMet synthetase), triphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant H14N	Escherichia coli	L-methionine	—	0.11	0.002	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant H14N, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)variant H14N	Escherichia coli	MgATP	2.3 × 10⁻⁴	0.07	0.0033	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant H14N, MgATP
S-adenosylmethionine synthetase (AdoMet synthetase)variant H14N	Escherichia coli	tripolyphosphatewithout AdoMet	0.0038	0.165	0.023	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant H14N, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant H14N	Escherichia coli	tripolyphosphate	0.038	0.028	1.4	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant H14N, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K165M	Escherichia coli	L-methionine	—	0.24	2.5	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K165M, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)variant K165M	Escherichia coli	MgATP	0.6	0.066	9.1	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K165M, MgATP
S-adenosylmethionine synthetase (AdoMet synthetase)variant K165M	Escherichia coli	tripolyphosphatewithout AdoMet	5.9	1.9	3	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K165M, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K165M	Escherichia coli	tripolyphosphate	0.98	0.375	2.6	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K165M, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K245M	Escherichia coli	L-methionine	—	0.095	3.4 × 10⁻⁴	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K245M, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)variant K245M	Escherichia coli	MgATP	3.6 × 10⁻⁵	0.082	4.5 × 10⁻⁴	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K245M, MgATP
S-adenosylmethionine synthetase (AdoMet synthetase)variant K245M	Escherichia coli	tripolyphosphate	0.0077	0.31	0.25	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K245M, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K265A	Escherichia coli	L-methionine	—	0.54	3.7 × 10⁻⁴	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K265A, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)variant K265A	Escherichia coli	MgATP	2 × 10⁻⁴	5.2	3.7 × 10⁻⁵	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K265A, MgATP
S-adenosylmethionine synthetase (AdoMet synthetase)variant K265A	Escherichia coli	tripolyphosphatewithout AdoMet	0.22	0.226	0.97	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K265A, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K265A	Escherichia coli	tripolyphosphate	0.25	0.031	8.1	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K265A, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K269M	Escherichia coli	L-methionine	—	7.1	1 × 10⁻⁴	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K269M, L-methionine
S-adenosylmethionine synthetase (AdoMet synthetase)variant K269M	Escherichia coli	MgATP	7.1 × 10⁻⁴	0.16	0.0044	pH 8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K269M, MgATP
S-adenosylmethionine synthetase (AdoMet synthetase)variant K269M	Escherichia coli	tripolyphosphatewithout AdoMet	0.014	0.02	0.68	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K269M, tripolyphosphate
S-adenosylmethionine synthetase (AdoMet synthetase)variant K269M	Escherichia coli	tripolyphosphate	0.045	0.0053	8.7	pH 7.8	PMID 10660564	Open record: S-adenosylmethionine synthetase (AdoMet synthetase) variant K269M, tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	adenosine 5'-triphosphate	—	0.073	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	L-methioninecosubstrate ATP	1.5	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), L-methionine
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.092	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), L-methionine
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	L-methionine	3	—	—	pH 8, 37 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), L-methionine
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	tripolyphosphateno AdoMet	0.06	0.003	20	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	1.2	0.013	92	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG)	Escherichia coli	adenosine 5'-triphosphate	—	0.087	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG)	Escherichia coli	L-methioninecosubstrate ATP	0.0078	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.77	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG)	Escherichia coli	tripolyphosphateno AdoMet	0.0023	0.0053	0.43	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	0.52	0.024	22	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G5-EcMAT (loop DRADPLEQ replaced by GGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG)	Escherichia coli	adenosine 5'-triphosphate	—	0.026	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG)	Escherichia coli	L-methioninecosubstrate ATP	0.0016	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.3	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG)	Escherichia coli	tripolyphosphateno AdoMet	0.022	0.0032	6.9	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	0.84	0.011	76	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G6-EcMAT (loop DRADPLEQ replaced by GGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG)	Escherichia coli	adenosine 5'-triphosphate	—	0.069	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG)	Escherichia coli	L-methioninecosubstrate ATP	0.0043	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.49	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG)	Escherichia coli	tripolyphosphateno AdoMet	0.044	0.0015	29	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	0.81	0.015	53	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G7-EcMAT (loop DRADPLEQ replaced by GGGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG)	Escherichia coli	adenosine 5'-triphosphate	—	0.045	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG)	Escherichia coli	L-methioninecosubstrate ATP	0.0024	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.62	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG)	Escherichia coli	tripolyphosphateno AdoMet	0.079	0.0016	49	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	1.2	0.008	150	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant G8-EcMAT (loop DRADPLEQ replaced by GGGGGGGG), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV)	Escherichia coli	adenosine 5'-triphosphate	—	0.045	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (EcMAT)variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV)	Escherichia coli	L-methioninecosubstrate ATP	0.0013	—	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV)	Escherichia coli	L-methioninecosubstrate ATP (saturating)	—	0.23	—	pH 8, 22 °C	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV), L-methionine
S-adenosylmethionine synthetase (EcMAT)variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV)	Escherichia coli	tripolyphosphateno AdoMet	0.044	0.014	3.3	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV), tripolyphosphate
S-adenosylmethionine synthetase (EcMAT)variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV)	Escherichia coli	tripolyphosphatewith 100 µM AdoMet (activator)	0.78	0.026	30	pH 7.8	PMID 12135357	Open record: S-adenosylmethionine synthetase (EcMAT) variant RLL-EcMAT (loop DRADPLEQ replaced by rat liver MAT sequence HLDRNEEDV), tripolyphosphate
S-adenosylmethionine synthetase (MAT)	Escherichia coli	adenosine 5'-triphosphate	—	0.17	—	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT), adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)	Escherichia coli	L-methionine	1.5	0.11	14 calc.	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT), L-methionine
S-adenosylmethionine synthetase (MAT)	Escherichia coli	L-methionine	1.22	0.08	15 calc.	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT), L-methionine
S-adenosylmethionine synthetase (MAT)	Escherichia coli	magnesium adenosine 5'-triphosphate	—	0.083	—	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT), magnesium adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant D107C	Escherichia coli	L-methionine	1.6	0.29	5.5 calc.	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant D107C, L-methionine
S-adenosylmethionine synthetase (MAT)variant D107C	Escherichia coli	L-methionineD107C labeled at Cys107 with MTSL spin label (R1 side chain)	0.23	0.19	1.2 calc.	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant D107C, L-methionine
S-adenosylmethionine synthetase (MAT)variant D107C	Escherichia coli	magnesium adenosine 5'-triphosphate	—	0.13	—	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant D107C, magnesium adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant D107C	Escherichia coli	magnesium adenosine 5'-triphosphateD107C labeled at Cys107 with MTSL spin label (R1 side chain)	—	0.18	—	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant D107C, magnesium adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant G105C	Escherichia coli	L-methionine	1.6	0.45	3.6 calc.	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant G105C, L-methionine
S-adenosylmethionine synthetase (MAT)variant G105C	Escherichia coli	L-methionineG105C labeled at Cys105 with MTSL spin label (R1 side chain)	1.4	0.75	1.9 calc.	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant G105C, L-methionine
S-adenosylmethionine synthetase (MAT)variant G105C	Escherichia coli	magnesium adenosine 5'-triphosphate	—	0.13	—	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant G105C, magnesium adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant G105C	Escherichia coli	magnesium adenosine 5'-triphosphateG105C labeled at Cys105 with MTSL spin label (R1 side chain)	—	0.18	—	pH 8, 22 °C	PMID 12831838	Open record: S-adenosylmethionine synthetase (MAT) variant G105C, magnesium adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant I303V	Escherichia coli	adenosine 5'-triphosphate	—	0.1	—	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V, adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant I303V	Escherichia coli	L-methionine	1.3	0.42	3.1 calc.	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V, L-methionine
S-adenosylmethionine synthetase (MAT)variant I303V/I65V	Escherichia coli	adenosine 5'-triphosphate	—	0.05	—	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V, adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant I303V/I65V	Escherichia coli	L-methionine	1.94	0.43	4.5 calc.	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V, L-methionine
S-adenosylmethionine synthetase (MAT)variant I303V/I65V/L186V	Escherichia coli	adenosine 5'-triphosphate	—	0.01	—	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V/L186V, adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant I303V/I65V/L186V	Escherichia coli	L-methionine	3.28	0.3	11 calc.	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V/L186V, L-methionine
S-adenosylmethionine synthetase (MAT)variant I303V/I65V/L186V/N104K	Escherichia coli	adenosine 5'-triphosphate	—	0.01	—	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V/L186V/N104K, adenosine 5'-triphosphate
S-adenosylmethionine synthetase (MAT)variant I303V/I65V/L186V/N104K	Escherichia coli	L-methionine	4.34	0.17	26 calc.	pH 8, 37 °C	PMID 31307578	Open record: S-adenosylmethionine synthetase (MAT) variant I303V/I65V/L186V/N104K, L-methionine