EC 6.2.1.1: acetate-CoA ligase

LigasesOpen in Browse

CatLog read 190 records for EC 6.2.1.1 from 10 papers, for 9 organisms. Names in these papers: acetyl-CoA synthetase (atACS), acetyl-CoA synthetase (MT-ACS1), Acetyl-CoA synthetase (Acs), acetyl-CoA synthetase Acs1 and 10 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 125 records for EC 6.2.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.2.1.1 in Browse.

Papers

Papers with records for EC 6.2.1.1
Paper	Organisms	Records
Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket	Arabidopsis thaliana	83
Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase	Methanothermobacter thermautotrophicus	35
Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase	Salmonella enterica	27
Role of motif III in catalysis by acetyl-CoA synthetase	Methanothermobacter thermautotrophicus	13
Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea	Metallosphaera sedula	13
Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation	Chloroflexus aurantiacus	6
Reaction mechanism and structural model of ADP-forming Acetyl-CoA synthetase from the hyperthermophilic archaeon Pyrococcus furiosus: evidence for a second active site histidine residue	Pyrococcus furiosus	4
In Salmonella enterica, the sirtuin-dependent protein acylation/deacylation system (SDPADS) maintains energy homeostasis during growth on low concentrations of acetate	Salmonella enterica, Salmonella enterica sv Typhimurium	4
Isolation and characterization of the acetyl-CoA synthetase from Penicillium chrysogenum. Involvement of this enzyme in the biosynthesis of penicillins	Penicillium chrysogenum	3
Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids	Homo sapiens	2

Records

Records for EC 6.2.1.1 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	3-hydroxypropionate	2.6	0.81	3.2	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), 3-hydroxypropionate
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	4-hydroxybutyrate	1.8	2	0.91	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), 4-hydroxybutyrate
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	Acetate	6.4	2.03	3.2	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Acetate
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	Butyrate	8.4	0.32	26	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Butyrate
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	Propionate	16.2	0.38	43	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Propionate
4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406)	Metallosphaera sedula	Valerate	5.6	0.74	7.5	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Valerate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	3-hydroxypropionate	0.08	1.88	0.04	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), 3-hydroxypropionate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	4-hydroxybutyrate	0.24	1.54	0.16	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), 4-hydroxybutyrate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	Acetate	0.14	0.68	0.2	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Acetate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	Butyrate	0.23	0.06	3.7	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Butyrate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	Propionate	0.21	0.54	0.39	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Propionate
4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394)	Metallosphaera sedula	Valerate	0.22	0.12	2	pH 7.9, 75 °C	PMID 23258541	Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Valerate
acetate/propionate-CoA synthetase (Msed_1353)variant W424G	Metallosphaera sedula	4-hydroxybutyrate	2.5	1.13	2.18	pH 7.9, 75 °C	PMID 23258541	Open record: acetate/propionate-CoA synthetase (Msed_1353) variant W424G, 4-hydroxybutyrate
acetyl-CoA synthetase	Penicillium chrysogenum	acetate	—	6.8	—	pH 8, 37 °C	PMID 1347531	Open record: acetyl-CoA synthetase, acetate
acetyl-CoA synthetase	Penicillium chrysogenum	adenosine 5'-triphosphate	—	17	—	pH 8, 37 °C	PMID 1347531	Open record: acetyl-CoA synthetase, adenosine 5'-triphosphate
acetyl-CoA synthetase	Penicillium chrysogenum	coenzyme A	—	0.18	—	pH 8, 37 °C	PMID 1347531	Open record: acetyl-CoA synthetase, coenzyme A
Acetyl-CoA synthetase (Acs)	Salmonella enterica	Acetate	276.8	6.047	45	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs), Acetate
Acetyl-CoA synthetase (Acs)	Salmonella enterica	ATP	100.6	0.0771	1.3 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs), ATP
Acetyl-CoA synthetase (Acs)	Salmonella enterica	CoA	95.1	0.05	1.9 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs), CoA
Acetyl-CoA synthetase (Acs)	Salmonella enterica	Glycine	259.4	9.45	27	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs), Glycine
Acetyl-CoA synthetase (Acs)	Salmonella enterica	Propionate	261	9.413	27	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs), Propionate
Acetyl-CoA synthetase (Acs)variant A357V	Salmonella enterica	ATP	38.9	0.0238	1.6 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant A357V, ATP
Acetyl-CoA synthetase (Acs)variant A357V	Salmonella enterica	CoA	35	0.133	300	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant A357V, CoA
Acetyl-CoA synthetase (Acs)variant D517G	Salmonella enterica	ATP	42.8	0.243	200	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant D517G, ATP
Acetyl-CoA synthetase (Acs)variant D517G	Salmonella enterica	CoA	42.4	0.228	200	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant D517G, CoA
Acetyl-CoA synthetase (Acs)variant D517P	Salmonella enterica	ATP	40.9	0.044	900	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant D517P, ATP
Acetyl-CoA synthetase (Acs)variant D517P	Salmonella enterica	CoA	43.8	0.5278	80	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant D517P, CoA
Acetyl-CoA synthetase (Acs)variant G524S	Salmonella enterica	ATP	49.8	0.0638	800	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant G524S, ATP
Acetyl-CoA synthetase (Acs)variant G524S	Salmonella enterica	CoA	43.1	0.448	100	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant G524S, CoA
Acetyl-CoA synthetase (Acs)variant R194A	Salmonella enterica	ATP	39.9	0.0287	1.4 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R194A, ATP
Acetyl-CoA synthetase (Acs)variant R194A	Salmonella enterica	CoA	41.1	0.1417	300	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R194A, CoA
Acetyl-CoA synthetase (Acs)variant R194E	Salmonella enterica	ATP	41.7	0.0373	1.1 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R194E, ATP
Acetyl-CoA synthetase (Acs)variant R194E	Salmonella enterica	CoA	40	0.1072	400	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R194E, CoA
Acetyl-CoA synthetase (Acs)variant R526A	Salmonella enterica	ATP	37.4	0.0224	1.7 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R526A, ATP
Acetyl-CoA synthetase (Acs)variant R526A	Salmonella enterica	CoA	40.5	0.205	200	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R526A, CoA
Acetyl-CoA synthetase (Acs)variant R584A	Salmonella enterica	ATP	46.7	0.0381	1.2 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R584A, ATP
Acetyl-CoA synthetase (Acs)variant R584A	Salmonella enterica	CoA	41.5	0.3583	100	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R584A, CoA
Acetyl-CoA synthetase (Acs)variant R584E	Salmonella enterica	ATP	36.4	0.0265	1.4 × 10³	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R584E, ATP
Acetyl-CoA synthetase (Acs)variant R584E	Salmonella enterica	CoA	40.8	0.426	90	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant R584E, CoA
Acetyl-CoA synthetase (Acs)variant V310D	Salmonella enterica	Acetate	232	2.464	90	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant V310D, Acetate
Acetyl-CoA synthetase (Acs)variant V310D	Salmonella enterica	Glycine	165.5	8.367	20	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant V310D, Glycine
Acetyl-CoA synthetase (Acs)variant V386A	Salmonella enterica	Acetate	183.5	6.403	28	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant V386A, Acetate
Acetyl-CoA synthetase (Acs)variant V386A	Salmonella enterica	Propionate	93.4	1.539	60	pH 7.5, 37 °C	PMID 17497934	Open record: Acetyl-CoA synthetase (Acs) variant V386A, Propionate
acetyl-CoA synthetase (AMP-forming), Acsvariant G266S	Salmonella enterica	acetate	—	11	—	37 °C	PMID 21306440	Open record: acetyl-CoA synthetase (AMP-forming), Acs variant G266S, acetate
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	acetateTris-HCl extraction buffer preparation	2.41	0.27	8.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), acetate
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	acetateHEPES extraction buffer preparation	5.7	0.12	48	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), acetate
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	adenosine 5'-triphosphateTris-HCl extraction buffer preparation	3.56	0.2	18 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	adenosine 5'-triphosphateHEPES extraction buffer preparation	16.04	0.05	320 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	coenzyme ATris-HCl extraction buffer preparation	3.47	0.15	23 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), coenzyme A
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	coenzyme AHEPES extraction buffer preparation	16.03	0.11	150 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), coenzyme A
acetyl-CoA synthetase (atACS)	Arabidopsis thaliana	propionate	0.66	4	0.16	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS), propionate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	2-methylpropanoate	3.2	110	0.03	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, 2-methylpropanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	3-methylpentanoate	1.9	1.5	1.22	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, 3-methylpentanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	4-methylhexanoate	1.5	1	1.6	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, 4-methylhexanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	4-methylpentanoate	6.7	4.3	1.57	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, 4-methylpentanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	adenosine 5'-triphosphate	1.6	0.11	15 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	coenzyme A	1.45	0.04	36 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, coenzyme A
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	heptanoate	2.22	1.05	2.11	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, heptanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	hexanoate	2.67	0.58	4.62	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, hexanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	octanoate	6.1	4.1	1.47	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, octanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	pentanoate	2.7	2.3	1.2	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, pentanoate
acetyl-CoA synthetase (atACS)variant I323A/V399A/W427G	Arabidopsis thaliana	propionate	3.3	98	0.03	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399A/W427G, propionate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	3-methylpentanoate	2.5	3.01	0.8	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, 3-methylpentanoate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	4-methylpentanoate	3	1.2	2.4	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, 4-methylpentanoate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	butyrate	3.8	4.5	0.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, butyrate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	heptanoate	5.4	5	1.1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, heptanoate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	hexanoate	4.8	7.8	0.62	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, hexanoate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	octanoate	4.5	2.4	1.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, octanoate
acetyl-CoA synthetase (atACS)variant I323A/V399G/W427G	Arabidopsis thaliana	pentanoate	2.2	2.1	1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant I323A/V399G/W427G, pentanoate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	2-methylpropanoate	0.23	0.15	1.6	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, 2-methylpropanoate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	3-methylpentanoate	0.077	0.04	1.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, 3-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	4-methylpentanoate	0.17	0.07	2.4	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, 4-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	acetate	1.91	0.18	10.4	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, acetate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	butyrate	0.13	0.19	0.68	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, butyrate
acetyl-CoA synthetase (atACS)variant T324G	Arabidopsis thaliana	propionate	1.78	3.2	0.56	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G, propionate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	2-methylpropanoate	4	219	0.018	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, 2-methylpropanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	3-methylpentanoate	7.7	2.7	2.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, 3-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	4-methylhexanoateHEPES extraction buffer preparation	5.9	0.25	24 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, 4-methylhexanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	4-methylhexanoateN-terminally His-tagged recombinant full-length atACS	—	—	2	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, 4-methylhexanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	4-methylpentanoate	6.6	0.22	29	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, 4-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	acetate	0.6	7.8	0.07	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, acetate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	adenosine 5'-triphosphate	5.04	0.26	19 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	butyrate	6.7	20	0.33	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, butyrate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	coenzyme A	5.07	0.14	36 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, coenzyme A
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	heptanoate	11	0.71	15	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, heptanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	hexanoate	5.7	0.13	43	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, hexanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	octanoate	5.2	2.1	2.4	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, octanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	pentanoate	8.8	0.4	22	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, pentanoate
acetyl-CoA synthetase (atACS)variant T324G/V399A/W427G	Arabidopsis thaliana	propionate	3.3	98	0.03	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324G/V399A/W427G, propionate
acetyl-CoA synthetase (atACS)variant T324S/V399A/W427G	Arabidopsis thaliana	4-methylpentanoate	8.2	1.2	6.7	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324S/V399A/W427G, 4-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324S/V399A/W427G	Arabidopsis thaliana	butyrate	19	16	1.2	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324S/V399A/W427G, butyrate
acetyl-CoA synthetase (atACS)variant T324S/V399A/W427G	Arabidopsis thaliana	pentanoate	7.2	1.5	4.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324S/V399A/W427G, pentanoate
acetyl-CoA synthetase (atACS)variant T324V	Arabidopsis thaliana	2-methylpropanoate	0.33	2.1	0.15	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324V, 2-methylpropanoate
acetyl-CoA synthetase (atACS)variant T324V	Arabidopsis thaliana	3-methylpentanoate	3.9	125	0.03	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324V, 3-methylpentanoate
acetyl-CoA synthetase (atACS)variant T324V	Arabidopsis thaliana	acetate	0.99	0.042	24	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324V, acetate
acetyl-CoA synthetase (atACS)variant T324V	Arabidopsis thaliana	propionate	1.1	0.62	1.8	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant T324V, propionate
acetyl-CoA synthetase (atACS)variant V399A	Arabidopsis thaliana	acetate	3.04	3.1	0.99	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A, acetate
acetyl-CoA synthetase (atACS)variant V399A	Arabidopsis thaliana	adenosine 5'-triphosphate	2.28	0.06	38 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A, adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)variant V399A	Arabidopsis thaliana	coenzyme A	3.2	0.09	36 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A, coenzyme A
acetyl-CoA synthetase (atACS)variant V399A	Arabidopsis thaliana	propionate	2.65	3.1	0.85	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A, propionate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	acetate	5.07	44	0.11	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, acetate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	adenosine 5'-triphosphate	6.17	0.06	100 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	butyrate	14.87	1.5	9.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, butyrate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	coenzyme A	8.04	0.09	89 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, coenzyme A
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	heptanoate	9.12	5.8	1.6	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, heptanoate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	hexanoate	9.2	7.3	1.3	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, hexanoate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	octanoate	3.04	6.3	0.48	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, octanoate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	pentanoate	12.25	4	3.1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, pentanoate
acetyl-CoA synthetase (atACS)variant V399A/W427G	Arabidopsis thaliana	propionate	12.94	31	0.41	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant V399A/W427G, propionate
acetyl-CoA synthetase (atACS)variant W427A	Arabidopsis thaliana	acetate	11	1.9	6	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427A, acetate
acetyl-CoA synthetase (atACS)variant W427A	Arabidopsis thaliana	butyrate	10.8	5.1	2.1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427A, butyrate
acetyl-CoA synthetase (atACS)variant W427A	Arabidopsis thaliana	propionate	21	23	0.9	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427A, propionate
acetyl-CoA synthetase (atACS)variant W427F	Arabidopsis thaliana	acetate	11.7	1.2	15.2	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427F, acetate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	acetate	14.3	10.8	1.32	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, acetate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	adenosine 5'-triphosphate	6.41	0.02	320 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, adenosine 5'-triphosphate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	butyrate	9.4	2.9	3.3	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, butyrate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	coenzyme A	9.36	0.14	67 calc.	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, coenzyme A
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	heptanoate	11	10	1.1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, heptanoate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	hexanoate	13	12.6	1.03	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, hexanoate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	octanoate	5.8	48	0.12	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, octanoate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	pentanoate	13.8	6.5	2.13	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, pentanoate
acetyl-CoA synthetase (atACS)variant W427G	Arabidopsis thaliana	propionate	6.2	37.5	0.16	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427G, propionate
acetyl-CoA synthetase (atACS)variant W427H	Arabidopsis thaliana	acetate	15	14	1.1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427H, acetate
acetyl-CoA synthetase (atACS)variant W427S	Arabidopsis thaliana	2-methylpropanoate	1.5	1.6	1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427S, 2-methylpropanoate
acetyl-CoA synthetase (atACS)variant W427S	Arabidopsis thaliana	acetate	7.2	8.9	0.81	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427S, acetate
acetyl-CoA synthetase (atACS)variant W427V	Arabidopsis thaliana	acetate	10.6	10	1	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427V, acetate
acetyl-CoA synthetase (atACS)variant W427V	Arabidopsis thaliana	propionate	2.5	38	0.06	pH 7.5, 37 °C	PMID 31117358	Open record: acetyl-CoA synthetase (atACS) variant W427V, propionate
acetyl-CoA synthetase (MT-ACS1)	Methanothermobacter thermautotrophicus	acetate	65.4	3.5	18.6	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1), acetate
acetyl-CoA synthetase (MT-ACS1)	Methanothermobacter thermautotrophicus	coenzyme A	—	0.19	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1), coenzyme A
acetyl-CoA synthetase (MT-ACS1)	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	3.3	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1), Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)	Methanothermobacter thermautotrophicus	propionate	46.3	36.5	1.3	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1), propionate
acetyl-CoA synthetase (MT-ACS1)variant I312A	Methanothermobacter thermautotrophicus	acetate	30.4	24.6	1.24	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant I312A, acetate
acetyl-CoA synthetase (MT-ACS1)variant I312A	Methanothermobacter thermautotrophicus	butyrate	0.47	136.4	0.0034	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant I312A, butyrate
acetyl-CoA synthetase (MT-ACS1)variant I312A	Methanothermobacter thermautotrophicus	coenzyme A	—	0.18	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant I312A, coenzyme A
acetyl-CoA synthetase (MT-ACS1)variant I312A	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	6.6	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant I312A, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant I312A	Methanothermobacter thermautotrophicus	propionate	18.2	73.1	0.25	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant I312A, propionate
acetyl-CoA synthetase (MT-ACS1)variant T313K	Methanothermobacter thermautotrophicus	acetate	1.9	596	0.0032 calc.	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313K, acetate
acetyl-CoA synthetase (MT-ACS1)variant T313K	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	3.4	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313K, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant T313V	Methanothermobacter thermautotrophicus	acetate	3.4	0.46	7.3	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313V, acetate
acetyl-CoA synthetase (MT-ACS1)variant T313V	Methanothermobacter thermautotrophicus	coenzyme A	—	0.7	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313V, coenzyme A
acetyl-CoA synthetase (MT-ACS1)variant T313V	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	0.65	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313V, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant T313V	Methanothermobacter thermautotrophicus	propionate	5.9	4.5	1.31	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant T313V, propionate
acetyl-CoA synthetase (MT-ACS1)variant V388A	Methanothermobacter thermautotrophicus	acetate	36.2	13.2	2.7	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388A, acetate
acetyl-CoA synthetase (MT-ACS1)variant V388A	Methanothermobacter thermautotrophicus	butyrate	1.56	151.9	0.01	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388A, butyrate
acetyl-CoA synthetase (MT-ACS1)variant V388A	Methanothermobacter thermautotrophicus	coenzyme A	—	0.35	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388A, coenzyme A
acetyl-CoA synthetase (MT-ACS1)variant V388A	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	2.6	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388A, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant V388A	Methanothermobacter thermautotrophicus	propionate	13.2	4.1	3.2	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388A, propionate
acetyl-CoA synthetase (MT-ACS1)variant V388G	Methanothermobacter thermautotrophicus	acetate	31.9	164.4	0.2	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388G, acetate
acetyl-CoA synthetase (MT-ACS1)variant V388G	Methanothermobacter thermautotrophicus	coenzyme A	—	0.18	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388G, coenzyme A
acetyl-CoA synthetase (MT-ACS1)variant V388G	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	4	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388G, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant V388G	Methanothermobacter thermautotrophicus	propionate	6	128.6	0.05	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant V388G, propionate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	3-methylvalerate	0.67	29.2	0.023	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, 3-methylvalerate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	4-methylvalerate	10.9	7.6	1.42	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, 4-methylvalerate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	acetate	33.7	132.1	0.26	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, acetate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	butyrate	10.8	39.2	0.27	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, butyrate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	coenzyme A	—	0.43	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, coenzyme A
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	heptanoate	7.3	10.2	0.72	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, heptanoate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	hexanoate	5.9	6.1	0.96	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, hexanoate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	Mg2+-ATP	—	2.3	—	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, Mg2+-ATP
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	octanoate	3.3	18.1	0.18	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, octanoate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	propionate	19.2	188.8	0.1	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, propionate
acetyl-CoA synthetase (MT-ACS1)variant W416G	Methanothermobacter thermautotrophicus	valerate	11.9	11.1	1.07	pH 7.5, 65 °C	PMID 16981708	Open record: acetyl-CoA synthetase (MT-ACS1) variant W416G, valerate
acetyl-CoA synthetase Acs1	Methanothermobacter thermautotrophicus	acetate	66.6	—	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1, acetate
acetyl-CoA synthetase Acs1variant A500T	Methanothermobacter thermautotrophicus	acetate	1.5	2.1	0.71 calc.	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant A500T, acetate
acetyl-CoA synthetase Acs1variant A500T	Methanothermobacter thermautotrophicus	adenosine 5'-triphosphate	—	3.6	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant A500T, adenosine 5'-triphosphate
acetyl-CoA synthetase Acs1variant A500T	Methanothermobacter thermautotrophicus	coenzyme A	—	0.51	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant A500T, coenzyme A
acetyl-CoA synthetase Acs1variant G501A	Methanothermobacter thermautotrophicus	acetate	0.3	1.4	0.21 calc.	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant G501A, acetate
acetyl-CoA synthetase Acs1variant G501A	Methanothermobacter thermautotrophicus	adenosine 5'-triphosphate	—	1.7	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant G501A, adenosine 5'-triphosphate
acetyl-CoA synthetase Acs1variant G501A	Methanothermobacter thermautotrophicus	coenzyme A	—	0.08	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant G501A, coenzyme A
acetyl-CoA synthetase Acs1variant T499A	Methanothermobacter thermautotrophicus	acetate	0.8	3	0.27 calc.	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant T499A, acetate
acetyl-CoA synthetase Acs1variant T499A	Methanothermobacter thermautotrophicus	adenosine 5'-triphosphate	—	1.7	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant T499A, adenosine 5'-triphosphate
acetyl-CoA synthetase Acs1variant T499A	Methanothermobacter thermautotrophicus	coenzyme A	—	0.24	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant T499A, coenzyme A
acetyl-CoA synthetase Acs1variant Y498A	Methanothermobacter thermautotrophicus	acetate	1.6	7.5	0.21 calc.	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant Y498A, acetate
acetyl-CoA synthetase Acs1variant Y498A	Methanothermobacter thermautotrophicus	adenosine 5'-triphosphate	—	1.7	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant Y498A, adenosine 5'-triphosphate
acetyl-CoA synthetase Acs1variant Y498A	Methanothermobacter thermautotrophicus	coenzyme A	—	0.1	—	pH 7.5, 65 °C	PMID 22973162	Open record: acetyl-CoA synthetase Acs1 variant Y498A, coenzyme A
acetyl-coenzyme A synthetase (Acs, AMP-forming)	Salmonella enterica sv Typhimurium	acetate	9.4	0.041	229	37 °C	PMID 21306440	Open record: acetyl-coenzyme A synthetase (Acs, AMP-forming), acetate
acetyl-coenzyme A synthetase (Acs, AMP-forming)variant G266S	Salmonella enterica sv Typhimurium	acetate	3.2	—	0.29	37 °C	PMID 21306440	Open record: acetyl-coenzyme A synthetase (Acs, AMP-forming) variant G266S, acetate
acetyl-coenzyme A synthetase (Acs, AMP-forming)variant L641P	Salmonella enterica sv Typhimurium	acetate	1.5	0.41	3.6	37 °C	PMID 21306440	Open record: acetyl-coenzyme A synthetase (Acs, AMP-forming) variant L641P, acetate
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)	Pyrococcus furiosus	acetyl coenzyme A	—	0.0042	—	pH 6.5, 80 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2), acetyl coenzyme A
ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2)	Pyrococcus furiosus	phosphate	—	0.23	—	pH 6.5, 80 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I (ACD I, α2β2), phosphate
ADP-forming acetyl-CoA synthetase isoenzyme I α-subunit (ACD I α, AcdIa)	Pyrococcus furiosus	acetyl coenzyme A	—	0.0037	—	pH 6.5, 80 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I α-subunit (ACD I α, AcdIa), acetyl coenzyme A
ADP-forming acetyl-CoA synthetase isoenzyme I α-subunit (ACD I α, AcdIa)	Pyrococcus furiosus	arsenate	—	15.19	—	pH 6.5, 80 °C	PMID 18372246	Open record: ADP-forming acetyl-CoA synthetase isoenzyme I α-subunit (ACD I α, AcdIa), arsenate
propionyl-CoA synthase	Chloroflexus aurantiacus	3-hydroxypropanoic acid	—	0.015	—	pH 7.8, 55 °C	PMID 11821399	Open record: propionyl-CoA synthase, 3-hydroxypropanoic acid
propionyl-CoA synthase	Chloroflexus aurantiacus	3-hydroxypropanoic acid	12	—	—	55 °C	PMID 11821399	Open record: propionyl-CoA synthase, 3-hydroxypropanoic acid
propionyl-CoA synthase	Chloroflexus aurantiacus	acrylate	—	0.5	—	pH 7.8, 55 °C	PMID 11821399	Open record: propionyl-CoA synthase, acrylate
propionyl-CoA synthase	Chloroflexus aurantiacus	ATP	—	0.05	—	pH 7.8, 55 °C	PMID 11821399	Open record: propionyl-CoA synthase, ATP
propionyl-CoA synthase	Chloroflexus aurantiacus	coenzyme A	—	0.01	—	pH 7.8, 55 °C	PMID 11821399	Open record: propionyl-CoA synthase, coenzyme A
propionyl-CoA synthase	Chloroflexus aurantiacus	NADPH	—	0.01	—	pH 7.8, 55 °C	PMID 11821399	Open record: propionyl-CoA synthase, NADPH
short-chain fatty acid:CoA ligase (SC-ligase)	Homo sapiens	butyrate	—	0.25	—	pH 8, 30 °C	PMID 10434065	Open record: short-chain fatty acid:CoA ligase (SC-ligase), butyrate
short-chain fatty acid:CoA ligase (SC-ligase)	Homo sapiens	propionate	—	0.285	—	pH 8, 30 °C	PMID 10434065	Open record: short-chain fatty acid:CoA ligase (SC-ligase), propionate