EC 1.1.1.145: 3beta-hydroxy-DELTA5-steroid dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 76 records for EC 1.1.1.145 from 5 papers, for 1 organism. Names in these papers: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1), 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1), 3β-hydroxysteroid dehydrogenase/isomerase type 1, type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) and 4 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 87 records for EC 1.1.1.145 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.145 in Browse.

Papers

Papers with records for EC 1.1.1.145
Paper	Organisms	Records
The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis	Homo sapiens	23
Structure/function of human type 1 3beta-hydroxysteroid dehydrogenase: An intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for substrate and…	Homo sapiens	22
Structure/function relationships responsible for the kinetic differences between human type 1 and type 2 3beta-hydroxysteroid dehydrogenase and for the catalysis of the type 1 activity	Homo sapiens	12
Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and…	Homo sapiens	11
Structure/function relationships responsible for coenzyme specificity and the isomerase activity of human type 1 3 beta-hydroxysteroid dehydrogenase/isomerase	Homo sapiens	8

Records

Records for EC 1.1.1.145 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
3β-hydroxysteroid dehydrogenase/isomerase type 1	Homo sapiens	17α-hydroxypregnenolone	—	0.0035	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1, 17α-hydroxypregnenolone
3β-hydroxysteroid dehydrogenase/isomerase type 1	Homo sapiens	dehydroepiandrosterone	0.062	0.0037	16.7	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1	Homo sapiens	NAD+	0.065	0.0341	1.8	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1, NAD+
3β-hydroxysteroid dehydrogenase/isomerase type 1	Homo sapiens	pregnenolone	—	0.0028	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1, pregnenolone
3β-hydroxysteroid dehydrogenase/isomerase type 1variant H156Y	Homo sapiens	17α-hydroxypregnenolone	—	0.0134	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 variant H156Y, 17α-hydroxypregnenolone
3β-hydroxysteroid dehydrogenase/isomerase type 1variant H156Y	Homo sapiens	dehydroepiandrosterone	0.12	0.0424	2.8	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 variant H156Y, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1variant H156Y	Homo sapiens	NAD+	0.077	0.025	3	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 variant H156Y, NAD+
3β-hydroxysteroid dehydrogenase/isomerase type 1variant H156Y	Homo sapiens	pregnenolone	—	0.0437	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 variant H156Y, pregnenolone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)	Homo sapiens	dehydroepiandrosterone	0.048	7 × 10⁻⁴	69	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1), dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)	0.048	0.012	4	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1), nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111A	Homo sapiens	dehydroepiandrosteronewithout β-mercaptoethanol (BME)	0.032	0.0268	1.2	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111A	Homo sapiens	dehydroepiandrosteronewith 10 mM β-mercaptoethanol (BME)	0.03	0.0237	1.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111A	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)without β-mercaptoethanol (BME)	0.035	0.0255	1.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111A, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111A	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)with 10 mM β-mercaptoethanol (BME)	0.032	0.0227	1.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111A, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111S	Homo sapiens	dehydroepiandrosteronewithout β-mercaptoethanol (BME)	0.087	0.0181	4.8	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111S, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111S	Homo sapiens	dehydroepiandrosteronewith 10 mM β-mercaptoethanol (BME)	0.087	0.0168	5.2	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111S, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111S	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)without β-mercaptoethanol (BME)	0.087	0.019	4.5	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111S, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C111S	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)with 10 mM β-mercaptoethanol (BME)	0.087	0.0166	5.2	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C111S, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72F	Homo sapiens	dehydroepiandrosteronewithout β-mercaptoethanol (BME)	0.053	0.0127	4.2	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72F, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72F	Homo sapiens	dehydroepiandrosteronewith 10 mM β-mercaptoethanol (BME)	0.05	0.0115	4.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72F, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72F	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)without β-mercaptoethanol (BME)	0.043	0.0468	1	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72F, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72F	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)with 10 mM β-mercaptoethanol (BME)	0.042	0.0476	0.83	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72F, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72S	Homo sapiens	dehydroepiandrosteronewithout β-mercaptoethanol (BME)	0.02	0.0028	7.2	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72S, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72S	Homo sapiens	dehydroepiandrosteronewith 10 mM β-mercaptoethanol (BME)	0.022	0.0044	3.8	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72S, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72S	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)without β-mercaptoethanol (BME)	0.022	0.0153	1.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72S, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C72S	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)with 10 mM β-mercaptoethanol (BME)	0.02	0.0194	1	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C72S, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C83A	Homo sapiens	dehydroepiandrosteronewithout β-mercaptoethanol (BME)	0.06	0.0171	3.5	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C83A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C83A	Homo sapiens	dehydroepiandrosteronewith 10 mM β-mercaptoethanol (BME)	0.047	0.0075	2.7	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C83A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C83A	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)without β-mercaptoethanol (BME)	0.063	0.0732	0.83	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C83A, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1)variant C83A	Homo sapiens	nicotinamide adenine dinucleotide (oxidized)with 10 mM β-mercaptoethanol (BME)	0.04	0.0299	1.3	pH 7.4, 27 °C	PMID 17624763	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 1 (3β-HSD1) variant C83A, nicotinamide adenine dinucleotide (oxidized)
3β-hydroxysteroid dehydrogenase/isomerase type 2	Homo sapiens	17α-hydroxypregnenolone	—	0.0178	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 2, 17α-hydroxypregnenolone
3β-hydroxysteroid dehydrogenase/isomerase type 2	Homo sapiens	dehydroepiandrosterone	0.115	0.0473	2.3	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 2, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/isomerase type 2	Homo sapiens	NAD+	0.118	0.0863	1.3	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 2, NAD+
3β-hydroxysteroid dehydrogenase/isomerase type 2	Homo sapiens	pregnenolone	—	0.0495	—	pH 7.4, 27 °C	PMID 12205101	Open record: 3β-hydroxysteroid dehydrogenase/isomerase type 2, pregnenolone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)	Homo sapiens	16α-hydroxydehydroepiandrosterone	0.097	0.0064	15	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1), 16α-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)	Homo sapiens	16β-hydroxydehydroepiandrosterone	0.048	0.0014	34.5	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1), 16β-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)	Homo sapiens	androst-5-ene-3,17-dione	—	—	30	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1), androst-5-ene-3,17-dione
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant D61N	Homo sapiens	androst-5-ene-3,17-dione	0.833	0.0288	29	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant D61N, androst-5-ene-3,17-dione
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant D61N	Homo sapiens	dehydroepiandrosterone	0.047	0.0047	10	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant D61N, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant D61N	Homo sapiens	NAD+	0.062	0.0643	1	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant D61N, NAD+
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant E192A	Homo sapiens	androst-5-ene-3,17-dione	0.282	0.0198	14.2	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant E192A, androst-5-ene-3,17-dione
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant E192A	Homo sapiens	dehydroepiandrosterone	0.03	0.0304	1	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant E192A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant E192A	Homo sapiens	NAD+	0.027	0.0351	0.83	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant E192A, NAD+
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant R195P	Homo sapiens	16α-hydroxydehydroepiandrosterone	0.155	0.0196	7.8	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant R195P, 16α-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant R195P	Homo sapiens	16β-hydroxydehydroepiandrosterone	0.155	0.015	10.3	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant R195P, 16β-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant R195P	Homo sapiens	dehydroepiandrosterone	0.128	0.0107	12	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant R195P, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant R195P	Homo sapiens	NAD+	0.1	0.0205	4.8	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant R195P, NAD+
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant T8A	Homo sapiens	androst-5-ene-3,17-dione	0.74	0.0279	26.5	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant T8A, androst-5-ene-3,17-dione
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant T8A	Homo sapiens	dehydroepiandrosterone	0.06	0.0082	7.3	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant T8A, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1)variant T8A	Homo sapiens	NAD+	0.045	0.0333	1.3	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 1 (3β-HSD1) variant T8A, NAD+
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)	Homo sapiens	16α-hydroxydehydroepiandrosterone	0.152	0.0148	10.2	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2), 16α-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)	Homo sapiens	16β-hydroxydehydroepiandrosterone	0.14	0.0184	7.7	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2), 16β-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)	Homo sapiens	dehydroepiandrosterone	0.145	0.0156	7.3	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2), dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)variant P195R	Homo sapiens	16α-hydroxydehydroepiandrosterone	0.077	0.004	19.2	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2) variant P195R, 16α-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)variant P195R	Homo sapiens	16β-hydroxydehydroepiandrosterone	0.053	0.0015	35.5	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2) variant P195R, 16β-hydroxydehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)variant P195R	Homo sapiens	dehydroepiandrosterone	0.093	0.0077	12.2	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2) variant P195R, dehydroepiandrosterone
3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2)variant P195R	Homo sapiens	NAD+	0.175	0.0564	3.2	pH 7.4, 27 °C	PMID 20420909	Open record: 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase type 2 (3β-HSD2) variant P195R, NAD+
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)	Homo sapiens	dehydroepiandrosterone	0.055	—	14.8	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1), dehydroepiandrosterone
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)	Homo sapiens	NAD+	0.058	—	1.7	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1), NAD+
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)variant Q105M	Homo sapiens	dehydroepiandrosterone	0.113	0.0405	2.8	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1) variant Q105M, dehydroepiandrosterone
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)variant Q105M	Homo sapiens	NAD+	0.038	0.0388	1	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1) variant Q105M, NAD+
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)variant Q240R	Homo sapiens	dehydroepiandrosterone	0.023	0.0061	3.8	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1) variant Q240R, dehydroepiandrosterone
human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1)variant Q240R	Homo sapiens	NAD+	0.022	0.0256	0.83	pH 7.4, 27 °C	PMID 15797861	Open record: human type 1 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD1) variant Q240R, NAD+
human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2)	Homo sapiens	dehydroepiandrosterone	0.118	—	2.5	pH 7.4, 27 °C	PMID 15797861	Open record: human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2), dehydroepiandrosterone
human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2)variant Q105M	Homo sapiens	dehydroepiandrosterone	0.075	0.025	3	pH 7.4, 27 °C	PMID 15797861	Open record: human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2) variant Q105M, dehydroepiandrosterone
human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2)variant Q105M	Homo sapiens	NAD+	0.145	0.0614	2.3	pH 7.4, 27 °C	PMID 15797861	Open record: human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2) variant Q105M, NAD+
human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2)variant R240Q	Homo sapiens	dehydroepiandrosterone	0.217	0.0327	6.7	pH 7.4, 27 °C	PMID 15797861	Open record: human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2) variant R240Q, dehydroepiandrosterone
human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2)variant R240Q	Homo sapiens	NAD+	0.187	0.0372	5	pH 7.4, 27 °C	PMID 15797861	Open record: human type 2 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD2) variant R240Q, NAD+
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)	Homo sapiens	dehydroepiandrosterone	0.055	0.0037	15 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity), dehydroepiandrosterone
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)	Homo sapiens	NAD+	0.065	0.0341	1.9 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity), NAD+
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D241N	Homo sapiens	dehydroepiandrosterone	0.022	0.0118	1.8 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D241N, dehydroepiandrosterone
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D241N	Homo sapiens	NAD+	0.017	0.0223	0.75 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D241N, NAD+
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D265N	Homo sapiens	dehydroepiandrosterone	0.0067	0.0106	0.63 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D265N, dehydroepiandrosterone
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D265N	Homo sapiens	NAD+	0.0067	0.0337	0.20 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D265N, NAD+
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D36A/K37R	Homo sapiens	dehydroepiandrosterone	0.018	0.0048	3.8 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D36A/K37R, dehydroepiandrosterone
type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity)variant D36A/K37R	Homo sapiens	NADP+	0.022	0.0206	1.1 calc.	pH 7.4, 27 °C	PMID 12832414	Open record: type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD activity) variant D36A/K37R, NADP+