EC 1.1.1.27: L-lactate dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 379 records for EC 1.1.1.27 from 23 papers, for 37 organisms. Names in these papers: L-lactate dehydrogenase, lactate dehydrogenase, L-lactate dehydrogenase (BSLDH), L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH) and 35 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 279 records for EC 1.1.1.27 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.27 in Browse.

Papers

Papers with records for EC 1.1.1.27
Paper	Organisms	Records
doi:10.1016/0305-0491(91)90248-c	Bufo calamita, Rana perezi	36
Threonine 246 at the active site of the L-lactate dehydrogenase of Bacillus stearothermophilus is important for catalysis but not for substrate binding	Bacillus stearothermophilus	35
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase	Homo sapiens	32
Improved specificity toward substrates with positively charged side chains by site-directed mutagenesis of the L-lactate dehydrogenase of Bacillus stearothermophilus	Bacillus stearothermophilus	25
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum	Homo sapiens, Plasmodium falciparum	25
Reappraisal of the regulation of lactococcal L-lactate dehydrogenase	Lactococcus lactis	24
Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and…	Lactobacillus casei ssp. casei, Lactobacillus curvatus	22
Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites	Plasmodium falciparum, Plasmodium malariae and 2 more	20
Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin	Gallus gallus, duck	20
The comparative enzymology of lactic dehydrogenases. 3. Properties of the H4 and M4 enzymes from a number of vertebrates	Anas platyrhynchos, Hippoglossus stenolepis and 8 more	20
The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum	Toxoplasma gondii	16
An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A	Enterococcus mundtii	16
Protein engineering tests of a homology model of Plasmodium falciparum lactate dehydrogenase	Bacillus stearothermophilus	15
Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid…	Sphyraena argentea, Sphyraena barracuda and 4 more	13
Partial purification and characterization of L-lactate dehydrogenase isozymes from sweet potato roots	Ipomoea batatas	10
A modified consensus approach to mutagenesis inverts the cofactor specificity of Bacillus stearothermophilus lactate dehydrogenase	Bacillus stearothermophilus	9
doi:10.1016/j.enzmictec.2008.10.009	Rhizopus delemar, Rhizopus oryzae	9
THE RELATIONSHIPS BETWEEN SUBSTRATES AND ENZYMES OF GLYCOLYSIS IN BRAIN	Mus musculus	8
Lactate dehydrogenase A exhibits sorbitol/fructose-related catalytic activity and contributes to polyol pathway metabolism in tumor cells	Homo sapiens	8
The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties - comparative modeling to probe the molecular basis	Lactococcus lactis	6
Directed modification of l-LcLDH1, an l-lactate dehydrogenase from Lactobacillus casei, to improve its specific activity and catalytic efficiency towards phenylpyruvic acid	Lactobacillus casei	6
Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions	—	2
Relative catalytic efficiencies and transcript levels of three d- and two l-lactate dehydrogenases for optically pure d-lactate production in Sporolactobacillus inulinus	Sporolactobacillus inulinus	2

Records

Records for EC 1.1.1.27 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
chicken heart lactate dehydrogenase	Gallus gallus	3-acetylpyridine adenine dinucleotide	1.6	0.05	30.3	pH 7.5, 25 °C	PMID 1989512	Open record: chicken heart lactate dehydrogenase, 3-acetylpyridine adenine dinucleotide
chicken heart lactate dehydrogenase	Gallus gallus	NAD+	12.1	0.25	48.2	pH 7.5, 25 °C	PMID 1989512	Open record: chicken heart lactate dehydrogenase, NAD+
chicken heart lactate dehydrogenase	Gallus gallus	nicotinamide 1,N6-ethenoadenine dinucleotide	6.2	0.57	10.1	pH 7.5, 25 °C	PMID 1989512	Open record: chicken heart lactate dehydrogenase, nicotinamide 1,N6-ethenoadenine dinucleotide
chicken heart lactate dehydrogenase	Gallus gallus	nicotinamide hypoxanthine dinucleotide	18.8	2.83	6.7	pH 7.5, 25 °C	PMID 1989512	Open record: chicken heart lactate dehydrogenase, nicotinamide hypoxanthine dinucleotide
chicken muscle lactate dehydrogenase	Gallus gallus	3-acetylpyridine adenine dinucleotide	1.6	0.5	2.7	pH 7.5, 25 °C	PMID 1989512	Open record: chicken muscle lactate dehydrogenase, 3-acetylpyridine adenine dinucleotide
chicken muscle lactate dehydrogenase	Gallus gallus	NAD+	3.3	0.7	4.7	pH 7.5, 25 °C	PMID 1989512	Open record: chicken muscle lactate dehydrogenase, NAD+
chicken muscle lactate dehydrogenase	Gallus gallus	nicotinamide 1,N6-ethenoadenine dinucleotide	0.7	2.4	0.3	pH 7.5, 25 °C	PMID 1989512	Open record: chicken muscle lactate dehydrogenase, nicotinamide 1,N6-ethenoadenine dinucleotide
chicken muscle lactate dehydrogenase	Gallus gallus	nicotinamide hypoxanthine dinucleotide	1.1	—	0.4	pH 7.5, 25 °C	PMID 1989512	Open record: chicken muscle lactate dehydrogenase, nicotinamide hypoxanthine dinucleotide
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.3	—	pH 6.5, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.1	—	pH 7, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.3	—	pH 7.4, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	3.3	—	pH 8, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.06	—	pH 6.5, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.07	—	pH 7, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.13	—	pH 7.4, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.2	—	pH 8, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PC3 cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	2.6	—	pH 6.5, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	2.1	—	pH 7, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	2	—	pH 7.4, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	1.5	—	pH 8, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), (S)-lactate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.03	—	pH 6.5, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.05	—	pH 7, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.09	—	pH 7.4, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), pyruvate
cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.21	—	pH 8, 25 °C	PMID 21042731	Open record: cytosolic L-lactate dehydrogenase (cLDH, PNT1A cells), pyruvate
L-lactate dehydrogenase	Bacillus stearothermophilus	2-oxobutanoic acid	124	0.4	310	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, 2-oxobutanoic acid
L-lactate dehydrogenase	Bacillus stearothermophilus	2-oxopentanoic acid	17	2.6	6.5	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, 2-oxopentanoic acid
L-lactate dehydrogenase	Bacillus stearothermophilus	3-hydroxy-2-oxopropanoic acid	162	0.43	380	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, 3-hydroxy-2-oxopropanoic acid
L-lactate dehydrogenase	Bacillus stearothermophilus	3-methyl-2-oxobutanoic acid	0.26	22	0.012	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, 3-methyl-2-oxobutanoic acid
L-lactate dehydrogenase	Bacillus stearothermophilus	3-phenyl-2-oxopropanoic acid	75	0.74	100	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, 3-phenyl-2-oxopropanoic acid
L-lactate dehydrogenase	Bacillus stearothermophilus	NADH	—	0.013	—	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Bacillus stearothermophilus	pyruvate5 mM FBP	166	0.04	4.2 × 10³	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Bacillus stearothermophilus	pyruvatewithout FBP (activator omitted)	247	5	49	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	2-oxobutanoic acid	1.7	0.44	3.9	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, 2-oxobutanoic acid
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	2-oxopentanoic acid	1.2	4.2	0.29	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, 2-oxopentanoic acid
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	3-hydroxy-2-oxopropanoic acid	20	1	20	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, 3-hydroxy-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	3-methyl-2-oxobutanoic acid	0.2	14	0.014	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, 3-methyl-2-oxobutanoic acid
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	3-phenyl-2-oxopropanoic acid	4.8	3.1	1.5	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, 3-phenyl-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	NADH	—	8 × 10⁻⁴	—	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, NADH
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	pyruvate5 mM FBP	5.1	0.045	110	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, pyruvate
L-lactate dehydrogenasevariant T246A	Bacillus stearothermophilus	pyruvatewithout FBP (activator omitted)	5.2	0.44	12	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246A, pyruvate
L-lactate dehydrogenasevariant T246L	Bacillus stearothermophilus	2-oxobutanoic acid	1	47	0.021	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246L, 2-oxobutanoic acid
L-lactate dehydrogenasevariant T246L	Bacillus stearothermophilus	2-oxopentanoic acid	0.09	50	0.0018	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246L, 2-oxopentanoic acid
L-lactate dehydrogenasevariant T246L	Bacillus stearothermophilus	3-phenyl-2-oxopropanoic acid	0.18	4.6	0.039	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246L, 3-phenyl-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246L	Bacillus stearothermophilus	pyruvate	10	40	0.25	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246L, pyruvate
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	2-oxobutanoic acid	40	1.1	36	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, 2-oxobutanoic acid
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	2-oxopentanoic acid	9.4	3.7	2.5	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, 2-oxopentanoic acid
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	3-hydroxy-2-oxopropanoic acid	74	0.54	140	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, 3-hydroxy-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	3-methyl-2-oxobutanoic acid	0.23	25	0.0092	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, 3-methyl-2-oxobutanoic acid
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	3-phenyl-2-oxopropanoic acid	25	1.8	14	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, 3-phenyl-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	NADH	—	0.0066	—	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, NADH
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	pyruvate5 mM FBP	132	0.07	1.9 × 10³	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, pyruvate
L-lactate dehydrogenasevariant T246S	Bacillus stearothermophilus	pyruvatewithout FBP (activator omitted)	133	10	13	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246S, pyruvate
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	2-oxobutanoic acid	6.9	4.8	1.4	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, 2-oxobutanoic acid
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	2-oxopentanoic acid	0.6	6.9	0.087	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, 2-oxopentanoic acid
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	3-hydroxy-2-oxopropanoic acid	78	9	8.6	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, 3-hydroxy-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	3-phenyl-2-oxopropanoic acid	2.7	2.7	1	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, 3-phenyl-2-oxopropanoic acid
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	NADH	—	7 × 10⁻⁴	—	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, NADH
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	pyruvate5 mM FBP	10	0.09	110	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, pyruvate
L-lactate dehydrogenasevariant T246V	Bacillus stearothermophilus	pyruvatewithout FBP (activator omitted)	11.8	0.97	12	pH 6, 25 °C	PMID 8251493	Open record: L-lactate dehydrogenase variant T246V, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.03	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.13	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.03	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.15	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.1	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.2	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.06	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.14	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.03	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.12	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH10 mM FBP (R state)	—	0.05	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	NADH50 mM Pi (T state)	—	0.15	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, NADH
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	1.4	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	18	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	1.1	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	2	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	0.4	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	3.4	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	1.1	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	4.1	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	2.8	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	6.6	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate10 mM FBP (R state)	—	2.4	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase	Lactococcus lactis	pyruvate50 mM Pi (T state)	—	4.4	—	pH 7.2, 30 °C	PMID 15006814	Open record: L-lactate dehydrogenase, pyruvate
L-lactate dehydrogenase (BSLDH)	Bacillus stearothermophilus	2-oxoadipate	5.3	1.6	3.3	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH), 2-oxoadipate
L-lactate dehydrogenase (BSLDH)	Bacillus stearothermophilus	4-amino-2-oxobutanoate	0.3	38	0.0079	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH), 4-amino-2-oxobutanoate
L-lactate dehydrogenase (BSLDH)	Bacillus stearothermophilus	6-amino-2-oxohexanoate	0.008	22	3.6 × 10⁻⁴	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH), 6-amino-2-oxohexanoate
L-lactate dehydrogenase (BsLDH)	Bacillus stearothermophilus	NAD+5 mM FBP (allosteric activator)	32	0.105	300	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH), NAD+
L-lactate dehydrogenase (BsLDH)	Bacillus stearothermophilus	NAD+no FBP	3.6	0.167	20	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH), NAD+
L-lactate dehydrogenase (BsLDH)variant C81S (S81)	Bacillus stearothermophilus	NAD+5 mM FBP (allosteric activator)	39	0.088	430	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant C81S (S81), NAD+
L-lactate dehydrogenase (BsLDH)variant C81S (S81)	Bacillus stearothermophilus	NAD+no FBP	3.9	0.248	15	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant C81S (S81), NAD+
L-lactate dehydrogenase (BsLDH)variant F16Q (Q16)	Bacillus stearothermophilus	NAD+5 mM FBP (allosteric activator)	38	0.065	590	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant F16Q (Q16), NAD+
L-lactate dehydrogenase (BsLDH)variant F16Q (Q16)	Bacillus stearothermophilus	NAD+no FBP	4.2	0.142	30	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant F16Q (Q16), NAD+
L-lactate dehydrogenase (BsLDH)variant F16Q/C81S/N85R (Mut31)	Bacillus stearothermophilus	NAD+5 mM FBP (allosteric activator)	23	0.0081	2.8 × 10³	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant F16Q/C81S/N85R (Mut31), NAD+
L-lactate dehydrogenase (BsLDH)variant F16Q/C81S/N85R (Mut31)	Bacillus stearothermophilus	NAD+no FBP	13	0.042	310	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant F16Q/C81S/N85R (Mut31), NAD+
L-lactate dehydrogenase (BsLDH)variant F16Q/I37K/D38S/C81S/N85R (Mut31 I37K:D38S)	Bacillus stearothermophilus	NADP+	23	4.7	5	pH 8, 25 °C	PMID 16012175	Open record: L-lactate dehydrogenase (BsLDH) variant F16Q/I37K/D38S/C81S/N85R (Mut31 I37K:D38S), NADP+
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxoadipate	3.6	3	1.2	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxoadipate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxobutanoate	42	5.1	8.2	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxobutanoate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxoglutarate	2.3	10.9	0.21	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxoglutarate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxohexanoate	16	3	5.3	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxohexanoate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxomalonate	9.5	11.4	0.83	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxomalonate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	2-oxopentanoate	16.2	7.3	2.2	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 2-oxopentanoate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	4-amino-2-oxobutanoate	0.6	19	0.032	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 4-amino-2-oxobutanoate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	6-amino-2-oxohexanoate	0.03	14	0.0021	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, 6-amino-2-oxohexanoate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	hydroxypyruvate	27.2	11	2.5	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, hydroxypyruvate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	phenylpyruvate	78	2.1	37	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, phenylpyruvate
L-lactate dehydrogenase (BSLDH)variant Q102D	Bacillus stearothermophilus	pyruvate	50	3.5	14	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102D, pyruvate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxoadipate	3.2	4.7	0.68	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxoadipate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxobutanoate	53	3.2	17	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxobutanoate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxoglutarate	3	12.1	0.25	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxoglutarate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxohexanoate	23	4.7	4.9	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxohexanoate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxomalonate	28	10.2	2.8	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxomalonate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	2-oxopentanoate	13.6	6.6	2.1	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 2-oxopentanoate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	4-amino-2-oxobutanoate	1.5	10	0.15	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 4-amino-2-oxobutanoate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	6-amino-2-oxohexanoate	0.1	11	0.009	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, 6-amino-2-oxohexanoate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	hydroxypyruvate	52.5	3.2	16	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, hydroxypyruvate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	phenylpyruvate	46	1.5	31	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, phenylpyruvate
L-lactate dehydrogenase (BSLDH)variant Q102E	Bacillus stearothermophilus	pyruvate	150	0.65	230	pH 6, 25 °C	PMID 7703235	Open record: L-lactate dehydrogenase (BSLDH) variant Q102E, pyruvate
L-lactate dehydrogenase (LDH)	—	2-oxobutanoate	—	—	1.8	pH 7.8, 25 °C	PMID 14503880	Open record: L-lactate dehydrogenase (LDH), 2-oxobutanoate
L-lactate dehydrogenase (LDH)	—	pyruvate	—	—	110	pH 7.8, 25 °C	PMID 14503880	Open record: L-lactate dehydrogenase (LDH), pyruvate
L-lactate dehydrogenase isozyme I	Ipomoea batatas	L-lactate	—	22	—	pH 8.8, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme I, L-lactate
L-lactate dehydrogenase isozyme I	Ipomoea batatas	NADH	—	0.0125	—	pH 7.3, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme I, NADH
L-lactate dehydrogenase isozyme I	Ipomoea batatas	pyruvate	—	0.34	—	pH 7.3, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme I, pyruvate
L-lactate dehydrogenase isozyme I	Ipomoea batatas	pyruvate	—	1.5	—	pH 6.5, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme I, pyruvate
L-lactate dehydrogenase isozyme II	Ipomoea batatas	DL-lactate	—	33	—	pH 8.2, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, DL-lactate
L-lactate dehydrogenase isozyme II	Ipomoea batatas	L-lactate	—	17	—	pH 8.2, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, L-lactate
L-lactate dehydrogenase isozyme II	Ipomoea batatas	NAD+	—	0.95	—	pH 8.2, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, NAD+
L-lactate dehydrogenase isozyme II	Ipomoea batatas	NADH	—	0.0125	—	pH 7.3, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, NADH
L-lactate dehydrogenase isozyme II	Ipomoea batatas	pyruvate	—	0.42	—	pH 7.3, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, pyruvate
L-lactate dehydrogenase isozyme II	Ipomoea batatas	pyruvate	—	0.5	—	pH 6.5, 25 °C	PMID 19425	Open record: L-lactate dehydrogenase isozyme II, pyruvate
L-lactate dehydrogenase L-LDH1	Sporolactobacillus inulinus	pyruvate	5.9	4.1	1.4	pH 7, 45 °C	PMID 30066438	Open record: L-lactate dehydrogenase L-LDH1, pyruvate
L-lactate dehydrogenase L-LDH2	Sporolactobacillus inulinus	pyruvate	2.3	6.8	0.3	pH 7, 40 °C	PMID 30066438	Open record: L-lactate dehydrogenase L-LDH2, pyruvate
L-lactate dehydrogenase LDH-1	Enterococcus mundtii	NADH	—	0.18	9 × 10³	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-1, NADH
L-lactate dehydrogenase LDH-1	Enterococcus mundtii	NADH	—	0.11	1.3 × 10⁴	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-1, NADH
L-lactate dehydrogenase LDH-1	Enterococcus mundtii	pyruvate	1.6 × 10³	0.93	1.7 × 10³	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-1, pyruvate
L-lactate dehydrogenase LDH-1	Enterococcus mundtii	pyruvate	1.5 × 10³	3.8	390	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-1, pyruvate
L-lactate dehydrogenase LDH-2	Enterococcus mundtii	NADH	—	0.41	4.4 × 10³	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2, NADH
L-lactate dehydrogenase LDH-2	Enterococcus mundtii	NADH	—	0.93	1.4 × 10³	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2, NADH
L-lactate dehydrogenase LDH-2	Enterococcus mundtii	pyruvate	1.8 × 10³	2.2	810	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2, pyruvate
L-lactate dehydrogenase LDH-2	Enterococcus mundtii	pyruvate	1.3 × 10³	2.7	480	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2, pyruvate
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	NADH3 mM FBP; 20 mM pyruvate fixed; NADH varied 0-1.5 mM	—	0.2	9 × 10³	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, NADH
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	NADHno FBP; NADH varied; pyruvate fixed	—	0.9	1.2 × 10³	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, NADH
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	NADH3 mM FBP; 20 mM pyruvate fixed; NADH varied 0-1.5 mM	—	0.26	6.8 × 10³	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, NADH
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	NADHno FBP; NADH varied; pyruvate fixed	—	—	200	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, NADH
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	pyruvate3 mM FBP; 1.5 mM NADH fixed; pyruvate varied 0-20 mM	1.8 × 10³	2.3	790	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, pyruvate
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	pyruvateno FBP; pyruvate varied; NADH fixed	—	15	59	pH 5.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, pyruvate
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	pyruvate3 mM FBP; 1.5 mM NADH fixed; pyruvate varied 0-20 mM	1.8 × 10³	3	610	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, pyruvate
L-lactate dehydrogenase LDH-2variant D241N	Enterococcus mundtii	pyruvateno FBP; pyruvate varied; NADH fixed	—	—	15	pH 7.5	PMID 25379380	Open record: L-lactate dehydrogenase LDH-2 variant D241N, pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	L-lactate	—	420	—	pH 7	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), L-lactate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	NADH	—	0.033	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), NADH
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	NADHwithout effectors (FDP and Mn2+ omitted)	—	0.1	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), NADH
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvate	—	12	—	pH 7	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvate	—	3	—	pH 6.2	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions no Mn2+ added; 0.3 mM FDP	—	0.74	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions no Mn2+ added; 3 mM FDP	—	0.65	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions 10 mM Mn2+; 3 mM FDP	—	0.71	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions no Mn2+ added; 0.3 mM FDP	—	0.55	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions no Mn2+ added; 3 mM FDP	—	0.49	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus casei ssp. casei	pyruvateeffector additions 10 mM Mn2+; 3 mM FDP	—	0.45	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	L-lactate	—	280	—	pH 7	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), L-lactate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	NADH	—	0.045	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), NADH
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvate	—	2.4	—	pH 7	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvate	—	1.1	—	pH 6.2	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions no Mn2+ added; no FDP added	—	66	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions no Mn2+ added; 3 mM FDP	—	1	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions 10 mM Mn2+; 3 mM FDP	—	0.83	—	pH 5.5	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions no Mn2+ added; no FDP added	—	14	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions no Mn2+ added; 3 mM FDP	—	0.66	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions 10 mM Mn2+; 3 mM FDP	—	0.66	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH)	Lactobacillus curvatus	pyruvateeffector additions 10 mM Mn2+; no FDP added	—	0.7	—	pH 4.8	PMID 14601	Open record: L-lactic acid dehydrogenase (allosteric, Mn2+ and FDP-activated, NAD-dependent L-LDH), pyruvate
L-LcLDH1	Lactobacillus casei	phenylpyruvic acidwithout D-FDP	94.7	8.23	11.5	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1, phenylpyruvic acid
L-LcLDH1	Lactobacillus casei	phenylpyruvic acidwith 3.0 mM D-FDP (allosteric activator)	6467	3.5	1848	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1, phenylpyruvic acid
L-LcLDH1variant I229A	Lactobacillus casei	phenylpyruvic acidwithout D-FDP	344.4	5.75	59.9	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1 variant I229A, phenylpyruvic acid
L-LcLDH1variant I229A	Lactobacillus casei	phenylpyruvic acidwith 3.0 mM D-FDP (allosteric activator)	1293	2.55	507.1	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1 variant I229A, phenylpyruvic acid
L-LcLDH1variant Q88R	Lactobacillus casei	phenylpyruvic acidwithout D-FDP	380.4	6.82	55.8	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1 variant Q88R, phenylpyruvic acid
L-LcLDH1variant Q88R	Lactobacillus casei	phenylpyruvic acidwith 3.0 mM D-FDP (allosteric activator)	17,479	1.86	9397	pH 5.5, 30 °C	PMID 29800600	Open record: L-LcLDH1 variant Q88R, phenylpyruvic acid
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.862	—	pH 7, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.567	—	pH 7.4, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.515	—	pH 8, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.803	—	pH 7, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.641	—	pH 7.4, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.616	—	pH 8, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.909	—	pH 7, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	0.94	—	pH 7.4, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	L-lactate	—	1.191	—	pH 8, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.018	—	pH 7, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.025	—	pH 7.4, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.057	—	pH 8, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.016	—	pH 7, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.039	—	pH 7.4, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.078	—	pH 8, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.061	—	pH 7, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.086	—	pH 7.4, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Bufo calamita	pyruvate	—	0.145	—	pH 8, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.735	—	pH 7, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.966	—	pH 7, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	1.333	—	pH 7, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.62	—	pH 7.4, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.537	—	pH 7.4, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	1.016	—	pH 7.4, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.541	—	pH 8, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.517	—	pH 8, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	L-lactate	—	0.822	—	pH 8, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, L-lactate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.027	—	pH 7, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.044	—	pH 7.4, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.11	—	pH 8, 15 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.033	—	pH 7, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.061	—	pH 7, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.054	—	pH 7.4, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.117	—	pH 7.4, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.171	—	pH 8, 20 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase	Rana perezi	pyruvate	—	0.312	—	pH 8, 30 °C	doi:10.1016/0305-0491(91)90248-c	Open record: lactate dehydrogenase, pyruvate
lactate dehydrogenase (bsLDH)	Bacillus stearothermophilus	4-methyl-2-oxopentanoate	0.33	6.6	0.05	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH), 4-methyl-2-oxopentanoate
lactate dehydrogenase (bsLDH)	Bacillus stearothermophilus	NADH	—	0.018	—	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH), NADH
lactate dehydrogenase (bsLDH)	Bacillus stearothermophilus	Phenylpyruvate	39.5	0.775	51	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH), Phenylpyruvate
lactate dehydrogenase (bsLDH)	Bacillus stearothermophilus	Pyruvate	180	0.06	3 × 10³	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH), Pyruvate
lactate dehydrogenase (bsLDH)	Bacillus stearothermophilus	pyruvate	177	0.056	3.2 × 10³ calc.	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH), pyruvate
lactate dehydrogenase (bsLDH)variant ELM1	Bacillus stearothermophilus	4-methyl-2-oxopentanoate	0.9	5.33	0.169	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM1, 4-methyl-2-oxopentanoate
lactate dehydrogenase (bsLDH)variant ELM1	Bacillus stearothermophilus	Phenylpyruvate	108	1.28	84	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM1, Phenylpyruvate
lactate dehydrogenase (bsLDH)variant ELM1	Bacillus stearothermophilus	Pyruvate	67.5	1.73	39	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM1, Pyruvate
lactate dehydrogenase (bsLDH)variant ELM2	Bacillus stearothermophilus	4-methyl-2-oxopentanoate	0.5	3.3	0.152	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM2, 4-methyl-2-oxopentanoate
lactate dehydrogenase (bsLDH)variant ELM2	Bacillus stearothermophilus	Phenylpyruvate	39.5	0.506	78	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM2, Phenylpyruvate
lactate dehydrogenase (bsLDH)variant ELM2	Bacillus stearothermophilus	Pyruvate	62.6	0.85	74	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant ELM2, Pyruvate
lactate dehydrogenase (bsLDH)variant S163A	Bacillus stearothermophilus	pyruvate	166	0.0998	1.66 × 10³ calc.	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant S163A, pyruvate
lactate dehydrogenase (bsLDH)variant S163L	Bacillus stearothermophilus	NADH	—	0.065	—	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant S163L, NADH
lactate dehydrogenase (bsLDH)variant S163L	Bacillus stearothermophilus	pyruvate	101	6.33	16.0 calc.	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant S163L, pyruvate
lactate dehydrogenase (bsLDH)variant SLELM	Bacillus stearothermophilus	pyruvate	1.5	12	0.12 calc.	pH 6, 25 °C	PMID 9051732	Open record: lactate dehydrogenase (bsLDH) variant SLELM, pyruvate
lactate dehydrogenase (pfLDH)	Plasmodium falciparum	3-acetylpyridine adenine dinucleotide	250	0.123	2 × 10³	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pfLDH), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase (pfLDH)	Plasmodium falciparum	L-lactate	65	12	5.5	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pfLDH), L-lactate
lactate dehydrogenase (pfLDH)	Plasmodium falciparum	NAD+	65	0.086	750	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pfLDH), NAD+
lactate dehydrogenase (pfLDH)	Plasmodium falciparum	NADH	148	0.007	2.2 × 10⁴	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pfLDH), NADH
lactate dehydrogenase (pfLDH)	Plasmodium falciparum	pyruvate	148	0.03	5 × 10³	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pfLDH), pyruvate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	2-oxobutanoate	180	0.47	380	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), 2-oxobutanoate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	3-acetylpyridine adenine dinucleotide	850	0.123	6.8 × 10³	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase (pLDH)	Plasmodium falciparum	Hydroxypyruvate	45	0.29	155	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), Hydroxypyruvate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	L-lactate	280	12	23	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), L-lactate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	L-lactatepurified from P. falciparum (clone D6) cultures	—	23	—	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), L-lactate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	NAD+	280	0.086	3.3 × 10³	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), NAD+
lactate dehydrogenase (pLDH)	Plasmodium falciparum	NAD+purified from P. falciparum (clone D6) cultures	—	0.102	—	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), NAD+
lactate dehydrogenase (pLDH)	Plasmodium falciparum	NADH	450	0.007	6.5 × 10⁴	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), NADH
lactate dehydrogenase (pLDH)	Plasmodium falciparum	NADHpurified from P. falciparum (clone D6) cultures	—	0.006	—	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), NADH
lactate dehydrogenase (pLDH)	Plasmodium falciparum	Pyruvate	450	0.03	1.5 × 10⁴	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), Pyruvate
lactate dehydrogenase (pLDH)	Plasmodium falciparum	Pyruvatepurified from P. falciparum (clone D6) cultures	—	0.016	—	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase (pLDH), Pyruvate
lactate dehydrogenase (pmLDH)	Plasmodium malariae	3-acetylpyridine adenine dinucleotide	230	0.168	1.33 × 10³	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pmLDH), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase (pmLDH)	Plasmodium malariae	L-lactate	38	11.3	3.3	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pmLDH), L-lactate
lactate dehydrogenase (pmLDH)	Plasmodium malariae	NAD+	38	0.143	270	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pmLDH), NAD+
lactate dehydrogenase (pmLDH)	Plasmodium malariae	NADH	125	0.009	900	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pmLDH), NADH
lactate dehydrogenase (pmLDH)	Plasmodium malariae	pyruvate	125	0.14	900	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pmLDH), pyruvate
lactate dehydrogenase (poLDH)	Plasmodium ovale	3-acetylpyridine adenine dinucleotide	153	0.408	380	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (poLDH), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase (poLDH)	Plasmodium ovale	L-lactate	25	93	0.27	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (poLDH), L-lactate
lactate dehydrogenase (poLDH)	Plasmodium ovale	NAD+	25	0.311	80	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (poLDH), NAD+
lactate dehydrogenase (poLDH)	Plasmodium ovale	NADH	270	0.014	3.8 × 10⁴	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (poLDH), NADH
lactate dehydrogenase (poLDH)	Plasmodium ovale	pyruvate	270	0.071	3.8 × 10³	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (poLDH), pyruvate
lactate dehydrogenase (pvLDH)	Plasmodium vivax	3-acetylpyridine adenine dinucleotide	330	0.182	1.8 × 10³	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pvLDH), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase (pvLDH)	Plasmodium vivax	L-lactate	23	10.2	2.3	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pvLDH), L-lactate
lactate dehydrogenase (pvLDH)	Plasmodium vivax	NAD+	23	0.155	150	pH 9.2, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pvLDH), NAD+
lactate dehydrogenase (pvLDH)	Plasmodium vivax	NADH	127	0.007	730	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pvLDH), NADH
lactate dehydrogenase (pvLDH)	Plasmodium vivax	pyruvate	127	0.017	7.3 × 10³	pH 7.5, 25 °C	PMID 15147206	Open record: lactate dehydrogenase (pvLDH), pyruvate
lactate dehydrogenase A (LDHA)	Homo sapiens	fructose	—	16.87	—	pH 8, 25 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), fructose
lactate dehydrogenase A (LDHA)	Homo sapiens	fructose	—	2.373	—	pH 8, 37 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), fructose
lactate dehydrogenase A (LDHA)	Homo sapiens	NADH	—	0.173	—	pH 8, 25 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), NADH
lactate dehydrogenase A (LDHA)	Homo sapiens	NADH	—	0.095	—	pH 8, 37 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), NADH
lactate dehydrogenase A (LDHA)	Homo sapiens	nicotinamide adenine dinucleotide (NAD+)	—	0.87	—	pH 8, 25 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), nicotinamide adenine dinucleotide (NAD+)
lactate dehydrogenase A (LDHA)	Homo sapiens	nicotinamide adenine dinucleotide (NAD+)	—	2.35	—	pH 8, 37 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), nicotinamide adenine dinucleotide (NAD+)
lactate dehydrogenase A (LDHA)	Homo sapiens	sorbitol	—	3.745	—	pH 8, 25 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), sorbitol
lactate dehydrogenase A (LDHA)	Homo sapiens	sorbitol	—	3.1	—	pH 8, 37 °C	PMID 42548485	Open record: lactate dehydrogenase A (LDHA), sorbitol
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	2-oxobutanoate	170	1	165	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), 2-oxobutanoate
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	3-acetylpyridine adenine dinucleotide	2.8	0.037	77	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	Hydroxypyruvate	270	0.32	850	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), Hydroxypyruvate
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	L-lactate	50	13	4	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), L-lactate
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	NAD+	50	0.037	1.35 × 10³	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), NAD+
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	NADH	220	0.008	2.7 × 10⁴	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), NADH
lactate dehydrogenase LDH-H (H4 isozyme)	Homo sapiens	Pyruvate	220	0.055	4 × 10³	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-H (H4 isozyme), Pyruvate
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	2-oxobutanoate	1.53 × 10³	6	250	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), 2-oxobutanoate
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	3-acetylpyridine adenine dinucleotide	4	0.056	70	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), 3-acetylpyridine adenine dinucleotide
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	Hydroxypyruvate	330	1.4	230	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), Hydroxypyruvate
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	L-lactate	82	11	7.2	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), L-lactate
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	NAD+	82	0.093	880	pH 9.2, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), NAD+
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	NADH	300	0.005	6 × 10⁴	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), NADH
lactate dehydrogenase LDH-M (M4 isozyme)	Homo sapiens	Pyruvate	300	0.17	1.8 × 10³	pH 7.5, 25 °C	PMID 9497046	Open record: lactate dehydrogenase LDH-M (M4 isozyme), Pyruvate
lactate dehydrogenase LDH1	Toxoplasma gondii	2-oxobutanoate	90	0.74	122	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, 2-oxobutanoate
lactate dehydrogenase LDH1	Toxoplasma gondii	3-acetylpyridine adenine dinucleotide (oxidized, APAD+)	570	0.05	1.13 × 10⁴	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, 3-acetylpyridine adenine dinucleotide (oxidized, APAD+)
lactate dehydrogenase LDH1	Toxoplasma gondii	3-hydroxypyruvate	50	0.77	67	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, 3-hydroxypyruvate
lactate dehydrogenase LDH1	Toxoplasma gondii	3-phenylpyruvate	50	0.69	72	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, 3-phenylpyruvate
lactate dehydrogenase LDH1	Toxoplasma gondii	L-lactate	27	8	3.3	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, L-lactate
lactate dehydrogenase LDH1	Toxoplasma gondii	NAD+	22	0.348	62	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, NAD+
lactate dehydrogenase LDH1	Toxoplasma gondii	NADH	620	0.0042	1.47 × 10⁵	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, NADH
lactate dehydrogenase LDH1	Toxoplasma gondii	pyruvate	580	0.12	4.8 × 10³	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH1, pyruvate
lactate dehydrogenase LDH2	Toxoplasma gondii	2-oxobutanoate	270	6.5	42	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, 2-oxobutanoate
lactate dehydrogenase LDH2	Toxoplasma gondii	3-acetylpyridine adenine dinucleotide (oxidized, APAD+)	220	0.078	2.8 × 10³	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, 3-acetylpyridine adenine dinucleotide (oxidized, APAD+)
lactate dehydrogenase LDH2	Toxoplasma gondii	3-hydroxypyruvate	180	22	8.3	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, 3-hydroxypyruvate
lactate dehydrogenase LDH2	Toxoplasma gondii	3-phenylpyruvate	950	2.4	400	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, 3-phenylpyruvate
lactate dehydrogenase LDH2	Toxoplasma gondii	L-lactate	97	54	1.8	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, L-lactate
lactate dehydrogenase LDH2	Toxoplasma gondii	NAD+	7.5	0.64	11.7	pH 9.2, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, NAD+
lactate dehydrogenase LDH2	Toxoplasma gondii	NADH	72	0.0019	3.8 × 10⁴	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, NADH
lactate dehydrogenase LDH2	Toxoplasma gondii	pyruvate	77	0.8	97	pH 7.5, 25 °C	PMID 11704270	Open record: lactate dehydrogenase LDH2, pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena argentea	pyruvate	—	0.369	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena argentea	β-nicotinamide adenine dinucleotide (reduced)	—	0.0196	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)	Sphyraena barracuda	pyruvate	—	0.19	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena barracuda	β-nicotinamide adenine dinucleotide (reduced)	—	0.0143	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)	Sphyraena ensis	β-nicotinamide adenine dinucleotide (reduced)	—	0.0142	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)	Sphyraena helleri	pyruvate	—	0.24	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena helleri	β-nicotinamide adenine dinucleotide (reduced)	—	0.016	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)	Sphyraena idiastes	β-nicotinamide adenine dinucleotide (reduced)	—	0.0189	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)	Sphyraena lucasana	pyruvatenative	—	0.258	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena lucasana	pyruvaterecombinant; expressed in E. coli BL21 (pGEMEX vector)	—	0.26	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), pyruvate
lactate dehydrogenase-A (LDH-A)	Sphyraena lucasana	β-nicotinamide adenine dinucleotide (reduced)	—	0.0186	—	25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A), β-nicotinamide adenine dinucleotide (reduced)
lactate dehydrogenase-A (LDH-A)variant D8G (C-8)	Sphyraena lucasana	pyruvate	—	0.283	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A) variant D8G (C-8), pyruvate
lactate dehydrogenase-A (LDH-A)variant V61A/G68S (C-61-68)	Sphyraena lucasana	pyruvate	—	0.37	—	pH 6.98, 25 °C	PMID 9115998	Open record: lactate dehydrogenase-A (LDH-A) variant V61A/G68S (C-61-68), pyruvate
lactic dehydrogenase	Mus musculus	NADH	—	0.0018	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, NADH
lactic dehydrogenase	Mus musculus	NADH	—	0.0026	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, NADH
lactic dehydrogenase	Mus musculus	NADH	—	0.0028	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, NADH
lactic dehydrogenase	Mus musculus	NADH	—	0.0039	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, NADH
lactic dehydrogenase	Mus musculus	pyruvate	—	0.14	—	pH 7.1, 38 °C	PMID 14114860	Open record: lactic dehydrogenase, pyruvate
lactic dehydrogenase	Mus musculus	pyruvateDPNH fixed at 2.5 µM	—	0.045	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, pyruvate
lactic dehydrogenase	Mus musculus	pyruvateDPNH fixed at 18 µM	—	0.082	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, pyruvate
lactic dehydrogenase	Mus musculus	pyruvateDPNH fixed at 117 µM	—	0.096	—	pH 7.1, 28 °C	PMID 14114860	Open record: lactic dehydrogenase, pyruvate
lactic dehydrogenase H4	Oryctolagus cuniculus	DL-lactate	—	7	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase H4, DL-lactate
lactic dehydrogenase H4	Oryctolagus cuniculus	sodium pyruvate	692	0.09	7.7 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase H4, sodium pyruvate
lactic dehydrogenase M4	Anas platyrhynchos	DL-lactate	—	16	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Anas platyrhynchos	sodium pyruvate	1.43 × 10³	0.15	9.6 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Hippoglossus stenolepis	DL-lactate	—	50	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Hippoglossus stenolepis	sodium pyruvate	2.65 × 10³	0.59	4.5 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Meleagris gallopavo	DL-lactate	—	18	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Meleagris gallopavo	sodium pyruvate	1.37 × 10³	0.22	6.2 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Phasianus colchicus	DL-lactate	—	18	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Phasianus colchicus	sodium pyruvate	1.47 × 10³	0.25	5.9 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Pterocnemia pennata	DL-lactate	—	18	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Pterocnemia pennata	sodium pyruvate	2.03 × 10³	0.2	1.0 × 10⁴ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Rana catesbeiana	DL-lactate	—	42	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Rana catesbeiana	sodium pyruvate	1.43 × 10³	0.14	1.0 × 10⁴ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Squalus acanthias	DL-lactate	—	55	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Squalus acanthias	sodium pyruvate	1.82 × 10³	0.33	5.5 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	Struthio camelus	DL-lactate	—	13	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	Struthio camelus	sodium pyruvate	1.75 × 10³	0.33	5.3 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
lactic dehydrogenase M4	tuna	DL-lactate	—	50	—	pH 8.9, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, DL-lactate
lactic dehydrogenase M4	tuna	sodium pyruvate	2.7 × 10³	0.91	2.9 × 10³ calc.	pH 7.5, 25 °C	PMID 6022861	Open record: lactic dehydrogenase M4, sodium pyruvate
LDH	Lactococcus lactis	NADH	—	0.054	—	pH 6, 30 °C	PMID 17944947	Open record: LDH, NADH
LDH	Lactococcus lactis	NADH	—	0.058	—	pH 7, 30 °C	PMID 17944947	Open record: LDH, NADH
LDH	Lactococcus lactis	pyruvate	—	1.5	—	pH 6, 30 °C	PMID 17944947	Open record: LDH, pyruvate
LDH	Lactococcus lactis	pyruvate	—	1.7	—	pH 7, 30 °C	PMID 17944947	Open record: LDH, pyruvate
LDHB	Lactococcus lactis	pyruvate	—	1.3	—	pH 6, 30 °C	PMID 17944947	Open record: LDHB, pyruvate
LDHB	Lactococcus lactis	pyruvate	—	2.9	—	pH 7, 30 °C	PMID 17944947	Open record: LDHB, pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	4	—	pH 6.5, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.8	—	pH 7, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.7	—	pH 7.4, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	(S)-lactate	—	2.6	—	pH 8, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.02	—	pH 6.5, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.05	—	pH 7, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.05	—	pH 7.4, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells)	Homo sapiens	pyruvate	—	0.19	—	pH 8, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PC3 cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	3.3	—	pH 6.5, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	1.8	—	pH 7, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	1.5	—	pH 7.4, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	(S)-lactate	—	3	—	pH 8, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), (S)-lactate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.015	—	pH 6.5, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.03	—	pH 7, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.04	—	pH 7.4, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), pyruvate
mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells)	Homo sapiens	pyruvate	—	0.15	—	pH 8, 25 °C	PMID 21042731	Open record: mitochondrial L-lactate dehydrogenase (mLDH, PNT1A cells), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB)	Rhizopus delemar	pyruvateNADH fixed at 125 µM	142	15	9.5	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB)	Rhizopus delemar	pyruvateNADH fixed at 150 µM	154	8.4	18.4	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB)	Rhizopus delemar	pyruvateNADH fixed at 200 µM	298	7.7	38.7	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB)	Rhizopus delemar	pyruvateNADH fixed at 250 µM	350	5	70	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RD-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB)	Rhizopus oryzae	lactate	—	47.4	—	pH 8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB), lactate
NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB)	Rhizopus oryzae	pyruvateNADH fixed at 125 µM	197	4.8	41.1	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB)	Rhizopus oryzae	pyruvateNADH fixed at 150 µM	244	2.8	87.2	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB)	Rhizopus oryzae	pyruvateNADH fixed at 200 µM	318	1.9	168	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB), pyruvate
NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB)	Rhizopus oryzae	pyruvateNADH fixed at 250 µM	320	1.3	246	pH 6.8, 30 °C	doi:10.1016/j.enzmictec.2008.10.009	Open record: NAD-dependent L-lactate dehydrogenase LdhB (RO-LdhB), pyruvate
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	3-acetylpyridine adenine dinucleotide	1.4	0.49	2.8	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), 3-acetylpyridine adenine dinucleotide
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	Bromopyruvate	269	0.62	434	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), Bromopyruvate
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	Fluoropyruvate	98	0.17	577	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), Fluoropyruvate
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	L-lactate	—	3.52	—	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), L-lactate
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	NAD+	6.9	0.49	14.2	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), NAD+
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	nicotinamide 1,N6-ethenoadenine dinucleotideNAD+ analog as coenzyme with L-lactate	5.3	1.17	4.5	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), nicotinamide 1,N6-ethenoadenine dinucleotide
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	nicotinamide 1,N6-ethenoadenine dinucleotideNAD+ analog and L-lactate both varied	—	1.14	—	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), nicotinamide 1,N6-ethenoadenine dinucleotide
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	nicotinamide hypoxanthine dinucleotideNAD+ analog as coenzyme with L-lactate	5.5	1.48	3.7	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), nicotinamide hypoxanthine dinucleotide
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	nicotinamide hypoxanthine dinucleotideNAD+ analog and L-lactate both varied	—	1.71	—	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), nicotinamide hypoxanthine dinucleotide
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	Pyruvate	204	0.095	2143	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), Pyruvate
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	Pyruvate ethyl ester	176	0.062	2839	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), Pyruvate ethyl ester
ε-crystallin (endogenous lactate dehydrogenase activity)	duck	Pyruvate methyl ester	227	0.104	2183	pH 7.5, 25 °C	PMID 1989512	Open record: ε-crystallin (endogenous lactate dehydrogenase activity), Pyruvate methyl ester