EC 1.1.1.37: (S)-malate dehydrogenase (NAD+, oxaloacetate-forming)

OxidoreductasesOpen in Browse

CatLog read 246 records for EC 1.1.1.37 from 27 papers, for 26 organisms. Names in these papers: mitochondrial malate dehydrogenase 1 (mMDH1), malate dehydrogenase (tMDH), Mdh2, malate dehydrogenase and 27 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 305 records for EC 1.1.1.37 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.37 in Browse.

Papers

Papers with records for EC 1.1.1.37
Paper	Organisms	Records
Adenine nucleotide-dependent and redox-independent control of mitochondrial malate dehydrogenase activity in Arabidopsis thaliana	Arabidopsis thaliana	24
Structural basis for the alteration of coenzyme specificity in a malate dehydrogenase mutant	Thermus flavus	22
Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1	Cupriavidus necator	22
Malate dehydrogenases of leaf tissue from Spinacia oleracea: properties of three isoenzymes	Spinacia oleracea	18
Purification and Characterisation of Malate Dehydrogenase From Synechocystis sp. PCC 6803: Biochemical Barrier of the Oxidative Tricarboxylic Acid Cycle	Synechocystis sp. PCC 6803	16
Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix	Aeropyrum pernix, Archaeoglobus fulgidus and 1 more	15
Purification and characterization of malate dehydrogenase from Corynebacterium glutamicum	Corynebacterium glutamicum	10
The NAD-linked aromatic alpha-hydroxy acid dehydrogenase from Trypanosoma cruzi. A new member of the cytosolic malate dehydrogenases group without malate dehydrogenase activity	Trypanosoma cruzi	8
Mitochondrial malate dehydrogenase from the thermophilic, filamentous fungus Talaromyces emersonii	Talaromyces emersonii	8
Purification, characterization, and overexpression of psychrophilic and thermolabile malate dehydrogenase of a novel antarctic psychrotolerant, Flavobacterium frigidimaris KUC-1	Flavobacterium frigidimaris	8
Allostery and Evolution: A Molecular Journey Through the Structural and Dynamical Landscape of an Enzyme Super Family	Methanopyrus kandleri	8
Malate dehydrogenase. Kinetic studies with meso-tartrate and 2-keto-3-hydroxysuccinate, comparison of the mitochondrial and supernatant pig heart enzymes	Sus scrofa (pig heart)	8
Kinetic characterization of mitochondrial malate dehydrogenase from Dictyostelium discoideum	Dictyostelium discoideum	8
Engineering a domain-locking disulfide into a bacterial malate dehydrogenase produces a redox-sensitive enzyme	Escherichia coli	8
Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum	Aquaspirillum arcticum, Escherichia coli and 1 more	7
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme	Plasmodium falciparum	7
Characterization of a cytosolic malate dehydrogenase cDNA which encodes an isozyme toward oxaloacetate reduction in wheat	Triticum aestivum	6
Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate	Homo sapiens	6
Cofactor engineering for improved production of 2,4-dihydroxybutyric acid via the synthetic homoserine pathway	Escherichia coli	6
Characterization of malate dehydrogenase from the hyperthermophilic archaeon Pyrobaculum islandicum	Pyrobaculum islandicum	5
Clonorchis sinensis: molecular cloning and functional expression of novel cytosolic malate dehydrogenase	Clonorchis sinensis	4
Identification and biochemical characterization of a thermostable malate dehydrogenase from the mesophile Streptomyces coelicolor A3(2)	Streptomyces coelicolor	4
Cloning, sequencing and functional expression of cytosolic malate dehydrogenase from Taenia solium: Purification and characterization of the recombinant enzyme	Taenia solium	4
Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase	Arabidopsis thaliana	4
Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis	Arabidopsis thaliana	4
Purification and characterization of malate dehydrogenase from the syntrophic propionate-oxidizing bacterium strain MPOB	syntrophic propionate-oxidizing bacterium strain MPOB	4
The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization	Ignicoccus islandicus	2

Records

Records for EC 1.1.1.37 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q)	Escherichia coli	2-oxo-4-hydroxybutyrate	74.89	1.84	44.91	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q), 2-oxo-4-hydroxybutyrate
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q)	Escherichia coli	NADH	36.48	0.04	1027	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q), NADH
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q)	Escherichia coli	NADPH	2.99	0.32	9.5	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D (Ec.Mdh5Q), NADPH
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q)	Escherichia coli	2-oxo-4-hydroxybutyrate	83.43	1.08	80.29	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q), 2-oxo-4-hydroxybutyrate
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q)	Escherichia coli	NADH	10.79	0.27	40.35	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q), NADH
(L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductasevariant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q)	Escherichia coli	NADPH	64.03	0.1	645.5	pH 7, 37 °C	PMID 40051839	Open record: (L)-malate dehydrogenase (Ec.Mdh), engineered OHB reductase variant I12V/R81A/M85Q/D86S/G179D/D34G/I35R (Ec.Mdh7Q), NADPH
AfMDH ((S)-malate dehydrogenase)	Archaeoglobus fulgidus	(2S,3R)-tartrate	0.33	0.4	0.83	pH 10, 50 °C	PMID 19555779	Open record: AfMDH ((S)-malate dehydrogenase), (2S,3R)-tartrate
AfMDH ((S)-malate dehydrogenase)	Archaeoglobus fulgidus	(2S,3S)-tartrate	1.2	0.63	2.3	pH 10, 50 °C	PMID 19555779	Open record: AfMDH ((S)-malate dehydrogenase), (2S,3S)-tartrate
AfMDH ((S)-malate dehydrogenase)	Archaeoglobus fulgidus	(S)-malate	5.7	0.074	77	pH 10, 50 °C	PMID 19555779	Open record: AfMDH ((S)-malate dehydrogenase), (S)-malate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(2S,3R)-tartrate4 mM NAD (Methods); cosubstrate NAD	0.16	0.2	0.8	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (2S,3R)-tartrate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(2S,3R)-tartrate1 mM NADP; cosubstrate NADP	0.2	5.8	0.034	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (2S,3R)-tartrate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(2S,3S)-tartrate4 mM NAD (Methods); cosubstrate NAD	0.37	1.2	0.31	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (2S,3S)-tartrate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(2S,3S)-tartrate1 mM NADP; cosubstrate NADP	4.1	23	0.18	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (2S,3S)-tartrate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(S)-malate4 mM NAD (Methods); cosubstrate NAD	2.6	0.12	22	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (S)-malate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	(S)-malate1 mM NADP; cosubstrate NADP	1.4	0.019	74	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), (S)-malate
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	NAD	2.8	0.87	3.2 calc.	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), NAD
ApeMDH ((S)-malate dehydrogenase)	Aeropyrum pernix	NADP	1.6	0.0076	210 calc.	pH 10, 50 °C	PMID 19555779	Open record: ApeMDH ((S)-malate dehydrogenase), NADP
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	4-hydroxyphenylpyruvate	2273	0.096	23,677		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), 4-hydroxyphenylpyruvate
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	4-hydroxyphenylpyruvaterecombinant; C-terminal Leu-Glu-His6 extension (pET24a(+)	1054	0.056	18,821		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), 4-hydroxyphenylpyruvate
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	NAD+	50.1	0.071	705.9		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), NAD+
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	NAD+recombinant; C-terminal Leu-Glu-His6 extension (pET24a(+)	31.4	0.042	747.6		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), NAD+
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	NADH	737	0.036	20,472		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), NADH
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	NADHrecombinant; C-terminal Leu-Glu-His6 extension (pET24a(+)	591	0.024	24,625		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), NADH
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	Phenyl lactate	35	0.425	82.3		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), Phenyl lactate
aromatic alpha-hydroxy acid dehydrogenase (AHADH)	Trypanosoma cruzi	Phenyl lactaterecombinant; C-terminal Leu-Glu-His6 extension (pET24a(+)	36.1	0.39	92.6		PMID 10583384	Open record: aromatic alpha-hydroxy acid dehydrogenase (AHADH), Phenyl lactate
cytosolic malate dehydrogenase (Cs-cMDH)	Clonorchis sinensis	malate	—	0.056	—	pH 9.6, 25 °C	PMID 15755419	Open record: cytosolic malate dehydrogenase (Cs-cMDH), malate
cytosolic malate dehydrogenase (Cs-cMDH)	Clonorchis sinensis	NAD	—	0.094	—	pH 9.6, 25 °C	PMID 15755419	Open record: cytosolic malate dehydrogenase (Cs-cMDH), NAD
cytosolic malate dehydrogenase (Cs-cMDH)	Clonorchis sinensis	NADH	—	0.007	—	pH 8.5, 25 °C	PMID 15755419	Open record: cytosolic malate dehydrogenase (Cs-cMDH), NADH
cytosolic malate dehydrogenase (Cs-cMDH)	Clonorchis sinensis	oxaloacetate	—	0.0096	—	pH 8.5, 25 °C	PMID 15755419	Open record: cytosolic malate dehydrogenase (Cs-cMDH), oxaloacetate
cytosolic malate dehydrogenase (r-TscMDH)	Taenia solium	L-malate	47.4	0.1	474	pH 9.6	PMID 21439955	Open record: cytosolic malate dehydrogenase (r-TscMDH), L-malate
cytosolic malate dehydrogenase (r-TscMDH)	Taenia solium	NADH	963	0.167	5.76 × 10³	pH 8	PMID 21439955	Open record: cytosolic malate dehydrogenase (r-TscMDH), NADH
cytosolic malate dehydrogenase (r-TscMDH)	Taenia solium	nicotinamide adenine dinucleotide (NAD+)	385.6	0.042	1.88 × 10³	pH 9.6	PMID 21439955	Open record: cytosolic malate dehydrogenase (r-TscMDH), nicotinamide adenine dinucleotide (NAD+)
cytosolic malate dehydrogenase (r-TscMDH)	Taenia solium	oxaloacetate	665.3	0.044	1.51 × 10⁴	pH 8	PMID 21439955	Open record: cytosolic malate dehydrogenase (r-TscMDH), oxaloacetate
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	L-malateTable 1	—	3.53	22.33		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), L-malate
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	L-malatein the text	78.82	—	—		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), L-malate
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	NAD+	—	0.69	153.6		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), NAD+
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	NADH	—	0.39	999.3		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), NADH
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	oxaloacetateTable 1	—	3.23	627.6		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), oxaloacetate
cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH)	Triticum aestivum	oxaloacetatein the text	2027	—	—		PMID 15388227	Open record: cytosolic NAD-dependent malate dehydrogenase (TaMDH, cyMDH), oxaloacetate
cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1)	Arabidopsis thaliana	NADHpre-reduced with 20 mM DTT for 1 h (cytMDH1Red)	677	0.072	9 × 10³	pH 7.5, 30 °C	PMID 29194485	Open record: cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1), NADH
cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1)	Arabidopsis thaliana	NADHpre-oxidized with 10 mM H2O2 at 30 °C for 45 min (cytMDH1Ox)	343	0.05	6.9 × 10³	pH 7.5, 30 °C	PMID 29194485	Open record: cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1), NADH
cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1)	Arabidopsis thaliana	oxaloacetatepre-reduced with 20 mM DTT for 1 h (cytMDH1Red)	608	0.238	2.6 × 10³	pH 7.5, 30 °C	PMID 29194485	Open record: cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1), oxaloacetate
cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1)	Arabidopsis thaliana	oxaloacetatepre-oxidized with 10 mM H2O2 at 30 °C for 45 min (cytMDH1Ox)	351	0.143	2.5 × 10³	pH 7.5, 30 °C	PMID 29194485	Open record: cytosolic NAD-dependent malate dehydrogenase 1 (cytMDH1), oxaloacetate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	3-phosphoglycerate	0.075	0.26	0.29 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), 3-phosphoglycerate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NAD+	—	0.022	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NAD+
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NADHcosubstrate oxaloacetate	—	0.004	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NADH
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	NADHcosubstrate α-ketoglutarate	—	0.004	—	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), NADH
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	oxaloacetate	0.177	6.5	0.027 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), oxaloacetate
D-3-phosphoglycerate dehydrogenase (PHGDH)	Homo sapiens	α-ketoglutarate	0.078	10.1	0.0078 calc.	pH 7.6, 37 °C	PMID 25406093	Open record: D-3-phosphoglycerate dehydrogenase (PHGDH), α-ketoglutarate
malate dehydrogenase	Flavobacterium frigidimaris	L-Malate	41.3	0.543	76	pH 10, 10 °C	PMID 16306697	Open record: malate dehydrogenase, L-Malate
malate dehydrogenase	Flavobacterium frigidimaris	L-Malate	48.4	0.269	180	pH 10, 20 °C	PMID 16306697	Open record: malate dehydrogenase, L-Malate
malate dehydrogenase	Flavobacterium frigidimaris	L-Malate	83.2	0.288	289	pH 10, 30 °C	PMID 16306697	Open record: malate dehydrogenase, L-Malate
malate dehydrogenase	Flavobacterium frigidimaris	L-Malate	138	0.74	187	pH 10, 40 °C	PMID 16306697	Open record: malate dehydrogenase, L-Malate
malate dehydrogenase	Flavobacterium frigidimaris	NAD+	41	0.0279	1.47 × 10³	pH 10, 10 °C	PMID 16306697	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	Flavobacterium frigidimaris	NAD+	48.6	0.0286	1.7 × 10³	pH 10, 20 °C	PMID 16306697	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	Flavobacterium frigidimaris	NAD+	83.4	0.0299	2.79 × 10³	pH 10, 30 °C	PMID 16306697	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	Flavobacterium frigidimaris	NAD+	139	0.0382	3.63 × 10³	pH 10, 40 °C	PMID 16306697	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	Pyrobaculum islandicum	malate	—	0.5	—	80 °C	PMID 17487443	Open record: malate dehydrogenase, malate
malate dehydrogenase	Pyrobaculum islandicum	NAD+	—	0.028	—	80 °C	PMID 17487443	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	Pyrobaculum islandicum	NADH	—	0.086	—	pH 8, 80 °C	PMID 17487443	Open record: malate dehydrogenase, NADH
malate dehydrogenase	Pyrobaculum islandicum	oxaloacetate	—	0.015	1.74 × 10⁴	pH 8, 80 °C	PMID 17487443	Open record: malate dehydrogenase, oxaloacetate
malate dehydrogenase	Pyrobaculum islandicum	oxaloacetate	—	0.01	—	80 °C	PMID 17487443	Open record: malate dehydrogenase, oxaloacetate
malate dehydrogenase	syntrophic propionate-oxidizing bacterium strain MPOB	L-malate	140	4	35 calc.	pH 9, 37 °C	PMID 8900056	Open record: malate dehydrogenase, L-malate
malate dehydrogenase	syntrophic propionate-oxidizing bacterium strain MPOB	NAD+	—	1.1	—	pH 9, 37 °C	PMID 8900056	Open record: malate dehydrogenase, NAD+
malate dehydrogenase	syntrophic propionate-oxidizing bacterium strain MPOB	NADH	—	0.03	—	pH 7.5, 37 °C	PMID 8900056	Open record: malate dehydrogenase, NADH
malate dehydrogenase	syntrophic propionate-oxidizing bacterium strain MPOB	oxaloacetate	1.36 × 10³	0.05	2.7 × 10⁴ calc.	pH 7.5, 37 °C	PMID 8900056	Open record: malate dehydrogenase, oxaloacetate
malate dehydrogenase (Aa MDH)	Aquaspirillum arcticum	NADH	152	0.016	1.1 × 10⁴	pH 7.5, 4 °C	PMID 10206992	Open record: malate dehydrogenase (Aa MDH), NADH
malate dehydrogenase (Aa MDH)	Aquaspirillum arcticum	NADH	277	0.023	1.2 × 10⁴	pH 7.5, 10 °C	PMID 10206992	Open record: malate dehydrogenase (Aa MDH), NADH
malate dehydrogenase (Aa MDH)	Aquaspirillum arcticum	NADH	1111	0.045	2.5 × 10⁴	pH 7.5, 37 °C	PMID 10206992	Open record: malate dehydrogenase (Aa MDH), NADH
malate dehydrogenase (Ec MDH)	Escherichia coli	NADH	93	0.023	4 × 10³	pH 7.5, 4 °C	PMID 10206992	Open record: malate dehydrogenase (Ec MDH), NADH
malate dehydrogenase (Ec MDH)	Escherichia coli	NADH	171	0.026	7 × 10³	pH 7.5, 10 °C	PMID 10206992	Open record: malate dehydrogenase (Ec MDH), NADH
malate dehydrogenase (Ec MDH)	Escherichia coli	NADH	1108	0.056	2 × 10⁴	pH 7.5, 37 °C	PMID 10206992	Open record: malate dehydrogenase (Ec MDH), NADH
malate dehydrogenase (LDH-like MalDH, I. isl MalDH)	Ignicoccus islandicus	oxaloacetate	444	0.38	1.2 × 10³	pH 7, 70 °C	PMID 31301348	Open record: malate dehydrogenase (LDH-like MalDH, I. isl MalDH), oxaloacetate
malate dehydrogenase (LDH-like MalDH, I. isl MalDH)	Ignicoccus islandicus	pyruvate	8	—	—	pH 6	PMID 31301348	Open record: malate dehydrogenase (LDH-like MalDH, I. isl MalDH), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/K173R/P250I (mutant 3; nnL numbering)	Methanopyrus kandleri	pyruvate50 mM KCl	26	—	—	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/K173R/P250I (mutant 3; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/K173R/P250I (mutant 3; nnL numbering)	Methanopyrus kandleri	pyruvate200 mM KCl	20	—	—	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/K173R/P250I (mutant 3; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/L163S/P250I (mutant 4; nnL numbering)	Methanopyrus kandleri	pyruvate50 mM KCl	120	—	—	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/L163S/P250I (mutant 4; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/L163S/P250I (mutant 4; nnL numbering)	Methanopyrus kandleri	pyruvate200 mM KCl	140	43	3.8	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/L163S/P250I (mutant 4; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/P250I (mutant 2; nnL numbering)	Methanopyrus kandleri	pyruvate50 mM KCl	20	—	—	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/P250I (mutant 2; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant D68H/R102Q/P250I (mutant 2; nnL numbering)	Methanopyrus kandleri	pyruvate200 mM KCl	20	—	—	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant D68H/R102Q/P250I (mutant 2; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant R102Q (mutant 1; nnL numbering)	Methanopyrus kandleri	pyruvate50 mM KCl	60	14	4.2	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant R102Q (mutant 1; nnL numbering), pyruvate
malate dehydrogenase (MalDH)variant R102Q (mutant 1; nnL numbering)	Methanopyrus kandleri	pyruvate200 mM KCl	70	23	3	pH 6, 60 °C	PMID 39834309	Open record: malate dehydrogenase (MalDH) variant R102Q (mutant 1; nnL numbering), pyruvate
malate dehydrogenase (MDH)	Corynebacterium glutamicum	L-malate	140	0.8	170	pH 10.5	PMID 16233457	Open record: malate dehydrogenase (MDH), L-malate
malate dehydrogenase (MDH)	Corynebacterium glutamicum	NAD+	110	0.4	270	pH 10.5	PMID 16233457	Open record: malate dehydrogenase (MDH), NAD+
malate dehydrogenase (MDH)	Corynebacterium glutamicum	NADH	200	0.07	2.8 × 10³	pH 6.5	PMID 16233457	Open record: malate dehydrogenase (MDH), NADH
malate dehydrogenase (MDH)	Corynebacterium glutamicum	NADH	390	0.041	9.5 × 10³	pH 8	PMID 16233457	Open record: malate dehydrogenase (MDH), NADH
malate dehydrogenase (MDH)	Corynebacterium glutamicum	NADH	720	0.1	7.2 × 10³	pH 9.5	PMID 16233457	Open record: malate dehydrogenase (MDH), NADH
malate dehydrogenase (MDH)	Corynebacterium glutamicum	NADPH	280	0.25	1.12 × 10³	pH 6.5	PMID 16233457	Open record: malate dehydrogenase (MDH), NADPH
malate dehydrogenase (MDH)	Corynebacterium glutamicum	oxaloacetate (oxalacetate)NADH-OAA reaction at its optimum pH 6.5; cosubstrate NADH	360	0.025	1.4 × 10⁴	pH 6.5	PMID 16233457	Open record: malate dehydrogenase (MDH), oxaloacetate (oxalacetate)
malate dehydrogenase (MDH)	Corynebacterium glutamicum	oxaloacetate (oxalacetate)	510	0.057	8.9 × 10³	pH 8	PMID 16233457	Open record: malate dehydrogenase (MDH), oxaloacetate (oxalacetate)
malate dehydrogenase (MDH)	Corynebacterium glutamicum	oxaloacetate (oxalacetate)	720	0.2	3.6 × 10³	pH 9.5	PMID 16233457	Open record: malate dehydrogenase (MDH), oxaloacetate (oxalacetate)
malate dehydrogenase (MDH)	Corynebacterium glutamicum	oxaloacetate (oxalacetate)NADPH-OAA reaction at its optimum pH 6.5; cosubstrate NADPH	150	0.55	270	pH 6.5	PMID 16233457	Open record: malate dehydrogenase (MDH), oxaloacetate (oxalacetate)
malate dehydrogenase (NAD-linked)	Escherichia coli	NADH	900	0.061	1.5 × 10⁴ calc.	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked), NADH
malate dehydrogenase (NAD-linked)	Escherichia coli	oxaloacetate	—	0.049	—	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked), oxaloacetate
malate dehydrogenase (NAD-linked)variant L305C	Escherichia coli	NADH	1.1 × 10³	0.087	1.3 × 10⁴ calc.	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant L305C, NADH
malate dehydrogenase (NAD-linked)variant L305C	Escherichia coli	oxaloacetate	—	0.044	—	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant L305C, oxaloacetate
malate dehydrogenase (NAD-linked)variant N122C/L305C	Escherichia coli	NADH	1.1 × 10³	0.056	2.0 × 10⁴ calc.	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant N122C/L305C, NADH
malate dehydrogenase (NAD-linked)variant N122C/L305C	Escherichia coli	NADH	130	0.052	2.5 × 10³ calc.	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant N122C/L305C, NADH
malate dehydrogenase (NAD-linked)variant N122C/L305C	Escherichia coli	oxaloacetate	—	0.34	—	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant N122C/L305C, oxaloacetate
malate dehydrogenase (NAD-linked)variant N122C/L305C	Escherichia coli	oxaloacetate	—	0.58	—	pH 7.5, 25 °C	PMID 7647229	Open record: malate dehydrogenase (NAD-linked) variant N122C/L305C, oxaloacetate
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	3-acetylpyridine adenine dinucleotide (paper: acetyl pyridine adenine dinucleotide)	175	0.37	470	pH 10.2	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), 3-acetylpyridine adenine dinucleotide (paper: acetyl pyridine adenine dinucleotide)
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	ketomalonate (mesoxalate, 2-oxopropanedioate)	674	5.44	120	pH 7.5	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), ketomalonate (mesoxalate, 2-oxopropanedioate)
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	Malate	250	1.35	180	pH 10.2	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), Malate
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	NAD	150	0.152	980	pH 10.2	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), NAD
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	NADH	950	0.036	2.6 × 10⁴	pH 7.5	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), NADH
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	oxaloacetate	960	0.03	3.2 × 10⁴	pH 7.5	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), oxaloacetate
malate dehydrogenase (Pf MDH)	Plasmodium falciparum	reduced 3-acetylpyridine adenine dinucleotide (paper: acetyl pyridine adenine dinucleotide, reduced form)	1.01 × 10³	0.022	4.5 × 10⁴	pH 7.5	PMID 15317584	Open record: malate dehydrogenase (Pf MDH), reduced 3-acetylpyridine adenine dinucleotide (paper: acetyl pyridine adenine dinucleotide, reduced form)
malate dehydrogenase (ScMDH)	Streptomyces coelicolor	L-malate	4.71	0.494	9.53	pH 8.5, 30 °C	PMID 21071865	Open record: malate dehydrogenase (ScMDH), L-malate
malate dehydrogenase (ScMDH)	Streptomyces coelicolor	NAD+	3.66	0.15	24.4	pH 8.5, 30 °C	PMID 21071865	Open record: malate dehydrogenase (ScMDH), NAD+
malate dehydrogenase (ScMDH)	Streptomyces coelicolor	NADH	542	0.083	6.56 × 10³	pH 8.5, 30 °C	PMID 21071865	Open record: malate dehydrogenase (ScMDH), NADH
malate dehydrogenase (ScMDH)	Streptomyces coelicolor	oxaloacetate	1.87 × 10³	0.189	1 × 10⁴	pH 8.5, 30 °C	PMID 21071865	Open record: malate dehydrogenase (ScMDH), oxaloacetate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	L-malateSupplementary Table S1	0.39	—	0.144	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), L-malate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	L-malateSupplementary Table S2	—	2.7	—	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), L-malate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	malateTable 1	0.43	—	0.165	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), malate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	malateTable 2	—	2.6	—	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), malate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	NADHTable 1	0.97	—	32.3	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), NADH
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	NADHTable 2	—	0.03	—	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), NADH
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	nicotinamide adenine dinucleotideSupplementary Table S1	0.67	—	0.674	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), nicotinamide adenine dinucleotide
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	nicotinamide adenine dinucleotideSupplementary Table S2	—	1	—	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), nicotinamide adenine dinucleotide
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	nicotinamide adenine dinucleotide (NAD+)Table 1	0.21	—	0.357	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), nicotinamide adenine dinucleotide (NAD+)
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	nicotinamide adenine dinucleotide (NAD+)Table 2	—	0.58	—	pH 8	PMID 30057585	Open record: malate dehydrogenase (SyMDH), nicotinamide adenine dinucleotide (NAD+)
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	oxaloacetate10 µg GST-SyMDH per 1 mL assay; A340; Lineweaver-Burk plot	0.71	—	59.5	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), oxaloacetate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	oxaloacetate10 µg GST-SyMDH per 1 mL assay; A340; Lineweaver-Burk plot	—	0.012	—	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), oxaloacetate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	oxaloacetateNADH oxidation followed at 340 nm; Supplementary Table S1	0.44	—	13.7	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), oxaloacetate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	oxaloacetateNADH oxidation followed at 340 nm; Supplementary Table S2	—	0.032	—	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), oxaloacetate
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	reduced nicotinamide adenine dinucleotideSupplementary Table S1	1.87	—	134	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), reduced nicotinamide adenine dinucleotide
malate dehydrogenase (SyMDH)	Synechocystis sp. PCC 6803	reduced nicotinamide adenine dinucleotideSupplementary Table S2	—	0.014	—	pH 6.5	PMID 30057585	Open record: malate dehydrogenase (SyMDH), reduced nicotinamide adenine dinucleotide
malate dehydrogenase (Tf MDH)	Thermus flavus	NADH	419	0.014	3 × 10⁴	pH 7.5, 37 °C	PMID 10206992	Open record: malate dehydrogenase (Tf MDH), NADH
malate dehydrogenase (tMDH)	Thermus flavus	NADH	122.4	0.0024	6.11 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH), NADH
malate dehydrogenase (tMDH)	Thermus flavus	NADPH	74.2	0.0426	1.7 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH), NADPH
malate dehydrogenase (tMDH)	Thermus flavus	oxaloacetateNADH; cosubstrate NADH	146.7	0.003	4.89 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH), oxaloacetate
malate dehydrogenase (tMDH)	Thermus flavus	oxaloacetateNADPH; cosubstrate NADPH	72.7	0.7402	100	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH), oxaloacetate
malate dehydrogenase (tMDH)	Thermus flavus	reduced nicotinamide hypoxanthine dinucleotide	297.5	0.0375	7.9 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH), reduced nicotinamide hypoxanthine dinucleotide
malate dehydrogenase (tMDH)variant EX3 (E41G/I42S/A45S)	Thermus flavus	NADH	98.1	0.0945	1 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX3 (E41G/I42S/A45S), NADH
malate dehydrogenase (tMDH)variant EX3 (E41G/I42S/A45S)	Thermus flavus	NADPH	140.5	0.0985	1.4 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX3 (E41G/I42S/A45S), NADPH
malate dehydrogenase (tMDH)variant EX3 (E41G/I42S/A45S)	Thermus flavus	oxaloacetateNADH; cosubstrate NADH	104.1	0.0317	3.3 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX3 (E41G/I42S/A45S), oxaloacetate
malate dehydrogenase (tMDH)variant EX3 (E41G/I42S/A45S)	Thermus flavus	oxaloacetateNADPH; cosubstrate NADPH	145.7	0.0054	2.7 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX3 (E41G/I42S/A45S), oxaloacetate
malate dehydrogenase (tMDH)variant EX4 (E41G/I42S/Q44R/A45S)	Thermus flavus	NADH	188.4	0.1641	1.1 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX4 (E41G/I42S/Q44R/A45S), NADH
malate dehydrogenase (tMDH)variant EX4 (E41G/I42S/Q44R/A45S)	Thermus flavus	NADPH	246.7	0.0051	4.83 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX4 (E41G/I42S/Q44R/A45S), NADPH
malate dehydrogenase (tMDH)variant EX4 (E41G/I42S/Q44R/A45S)	Thermus flavus	oxaloacetateNADH; cosubstrate NADH	111.1	0.015	1.26 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX4 (E41G/I42S/Q44R/A45S), oxaloacetate
malate dehydrogenase (tMDH)variant EX4 (E41G/I42S/Q44R/A45S)	Thermus flavus	oxaloacetateNADPH; cosubstrate NADPH	245.4	0.0117	2.1 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX4 (E41G/I42S/Q44R/A45S), oxaloacetate
malate dehydrogenase (tMDH)variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q)	Thermus flavus	NADH	173.4	0.1608	1.1 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q), NADH
malate dehydrogenase (tMDH)variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q)	Thermus flavus	NADPH	192.2	0.0275	7 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q), NADPH
malate dehydrogenase (tMDH)variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q)	Thermus flavus	oxaloacetateNADH; cosubstrate NADH	86.8	0.009	1.92 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q), oxaloacetate
malate dehydrogenase (tMDH)variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q)	Thermus flavus	oxaloacetateNADPH; cosubstrate NADPH	184.7	0.0353	4.8 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX6 (E41G/I42S/P43E/A45S/M46F/K47Q), oxaloacetate
malate dehydrogenase (tMDH)variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q)	Thermus flavus	NADH	80.2	0.0809	900	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q), NADH
malate dehydrogenase (tMDH)variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q)	Thermus flavus	NADPH	111.7	0.0074	1.51 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q), NADPH
malate dehydrogenase (tMDH)variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q)	Thermus flavus	oxaloacetateNADH; cosubstrate NADH	78.2	0.0317	2.5 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q), oxaloacetate
malate dehydrogenase (tMDH)variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q)	Thermus flavus	oxaloacetateNADPH; cosubstrate NADPH	112	0.0054	2.07 × 10⁴	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q), oxaloacetate
malate dehydrogenase (tMDH)variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q)	Thermus flavus	reduced nicotinamide hypoxanthine dinucleotide phosphate	70.4	0.0072	9.7 × 10³	pH 7, 30 °C	PMID 16828705	Open record: malate dehydrogenase (tMDH) variant EX7 (E41G/I42S/P43E/Q44R/A45S/M46F/K47Q), reduced nicotinamide hypoxanthine dinucleotide phosphate
malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes)	Dictyostelium discoideum	malate	—	5	—	pH 9.5, 25 °C	PMID 7142959	Open record: malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes), malate
malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes)	Dictyostelium discoideum	NAD	—	0.14	—	pH 9.5, 25 °C	PMID 7142959	Open record: malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes), NAD
malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes)	Dictyostelium discoideum	NADH	—	0.03	—	pH 9.5, 25 °C	PMID 7142959	Open record: malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes), NADH
malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes)	Dictyostelium discoideum	oxaloacetate	—	0.17	—	pH 9.5, 25 °C	PMID 7142959	Open record: malate dehydrogenase (whole-cell preparation containing mitochondrial and cytoplasmic isoenzymes), oxaloacetate
Mdh2	Cupriavidus necator	1-butanol	6.5	7.2	0.906	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, 1-butanol
Mdh2	Cupriavidus necator	1-propanol	9.6	0.54	17.76	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, 1-propanol
Mdh2	Cupriavidus necator	Ethanol	11.1	0.77	14.48	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, Ethanol
Mdh2	Cupriavidus necator	Methanol	0.22	132.1	0.0016	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, Methanol
Mdh2	Cupriavidus necator	MethanolB. methanolicus PB1 ACT	0.22	100.7	0.0022	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, Methanol
Mdh2	Cupriavidus necator	MethanolE. coli NudF	0.23	122.1	0.0019	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, Methanol
Mdh2	Cupriavidus necator	NAD+	0.24	0.93	0.258	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, NAD+
Mdh2	Cupriavidus necator	NAD+B. methanolicus PB1 ACT	0.2	0.93	0.215	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, NAD+
Mdh2	Cupriavidus necator	NAD+E. coli NudF	0.21	1.3	0.162	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2, NAD+
Mdh2variant A169C	Cupriavidus necator	Methanol	0.16	46	0.0035	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169C, Methanol
Mdh2variant A169I	Cupriavidus necator	Methanol	0.064	68.9	9.3 × 10⁻⁴	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169I, Methanol
Mdh2variant A169L	Cupriavidus necator	Methanol	0.093	201	4.6 × 10⁻⁴	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169L, Methanol
Mdh2variant A169M	Cupriavidus necator	Methanol	0.073	203	3.6 × 10⁻⁴	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169M, Methanol
Mdh2variant A169P	Cupriavidus necator	Methanol	0.41	303	0.0014	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169P, Methanol
Mdh2variant A169V	Cupriavidus necator	1-butanol	3.3	66.5	0.05	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169V, 1-butanol
Mdh2variant A169V	Cupriavidus necator	Methanol	0.13	26.9	0.0048	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A169V, Methanol
Mdh2variant A26V/A169V	Cupriavidus necator	1-butanol	5	75.9	0.066	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A26V/A169V, 1-butanol
Mdh2variant A26V/A169V	Cupriavidus necator	Methanol	0.21	30.7	0.0068	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A26V/A169V, Methanol
Mdh2variant A26V/A31V/A169V	Cupriavidus necator	1-butanol	5.7	120	0.048	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A26V/A31V/A169V, 1-butanol
Mdh2variant A26V/A31V/A169V	Cupriavidus necator	Methanol	0.2	21.6	0.0093	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A26V/A31V/A169V, Methanol
Mdh2variant A31V	Cupriavidus necator	1-butanol	7.2	11.3	0.637	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A31V, 1-butanol
Mdh2variant A31V	Cupriavidus necator	Methanol	0.25	129	0.0019	pH 9.5, 30 °C	PMID 26846745	Open record: Mdh2 variant A31V, Methanol
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	L-malate	—	2.84	—	pH 8.5	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), L-malate
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	nicotinamide adenine dinucleotide	—	0.364	—	pH 8.5	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), nicotinamide adenine dinucleotide
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	oxaloacetate	—	0.018	—	pH 6	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), oxaloacetate
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	oxaloacetate	—	0.039	—	pH 7.5	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), oxaloacetate
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	oxaloacetate	—	0.56	—	pH 9	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), oxaloacetate
microbody malate dehydrogenase (mb-MDH)	Spinacia oleracea	reduced nicotinamide adenine dinucleotide	—	0.024	—	pH 7.5	PMID 5114926	Open record: microbody malate dehydrogenase (mb-MDH), reduced nicotinamide adenine dinucleotide
mitochondrial malate dehydrogenase	Dictyostelium discoideum	malate	—	1.33	—	pH 9.5, 25 °C	PMID 7142959	Open record: mitochondrial malate dehydrogenase, malate
mitochondrial malate dehydrogenase	Dictyostelium discoideum	NAD	—	0.1	—	pH 9.5, 25 °C	PMID 7142959	Open record: mitochondrial malate dehydrogenase, NAD
mitochondrial malate dehydrogenase	Dictyostelium discoideum	NADH	—	0.04	—	pH 9.5, 25 °C	PMID 7142959	Open record: mitochondrial malate dehydrogenase, NADH
mitochondrial malate dehydrogenase	Dictyostelium discoideum	oxaloacetate	—	0.27	—	pH 9.5, 25 °C	PMID 7142959	Open record: mitochondrial malate dehydrogenase, oxaloacetate
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	L-malate	—	5.9	—	pH 8.5	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), L-malate
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	nicotinamide adenine dinucleotide	—	0.574	—	pH 8.5	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), nicotinamide adenine dinucleotide
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	oxaloacetate	—	0.0033	—	pH 6	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), oxaloacetate
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	oxaloacetate	—	0.041	—	pH 7.5	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), oxaloacetate
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	oxaloacetate	—	0.06	—	pH 9	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), oxaloacetate
mitochondrial malate dehydrogenase (m-MDH)	Spinacia oleracea	reduced nicotinamide adenine dinucleotide	—	0.0477	—	pH 7.5	PMID 5114926	Open record: mitochondrial malate dehydrogenase (m-MDH), reduced nicotinamide adenine dinucleotide
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	L-malatenative enzyme purified from T. emersonii mycelia	2.9 × 10³	1.25	2.32 × 10³	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), L-malate
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	L-malateexpressed in E. coli BL21-AI; Ni-NTA purified	3.5 × 10³	1	2.44 × 10³	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), L-malate
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	NAD+native enzyme purified from T. emersonii mycelia	2.77 × 10³	0.12	2.3 × 10⁴	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), NAD+
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	NAD+expressed in E. coli BL21-AI; Ni-NTA purified	3.1 × 10³	0.13	2.74 × 10⁴	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), NAD+
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	NADHnative enzyme purified from T. emersonii mycelia	1.1 × 10⁵	0.025	4.4 × 10⁶	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), NADH
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	NADHexpressed in E. coli BL21-AI; Ni-NTA purified	9 × 10⁴	0.029	4.8 × 10⁶	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), NADH
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	Oxaloacetatenative enzyme purified from T. emersonii mycelia	9.1 × 10⁴	0.02	4.5 × 10⁶	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), Oxaloacetate
mitochondrial malate dehydrogenase (m-MDH)	Talaromyces emersonii	Oxaloacetateexpressed in E. coli BL21-AI; Ni-NTA purified	8.1 × 10⁴	0.022	5.1 × 10⁶	pH 7.4, 30 °C	PMID 15265031	Open record: mitochondrial malate dehydrogenase (m-MDH), Oxaloacetate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	2-ketoglutarate	223.3	—	—	pH 7.4, 25 °C	PMID 26203119	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), 2-ketoglutarate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malatecontrol (reduced) enzyme	—	0.81	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malate	—	0.77	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malateno adenine nucleotide (control)	—	0.72	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malatewith 1 mM AMP	—	1.11	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malatewith 1 mM ADP	—	1.22	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	malatewith 1 mM ATP	—	1.56	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), malate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)control (reduced) enzyme	—	0.6	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)	—	0.61	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)no adenine nucleotide (control)	—	0.58	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)with 1 mM AMP	—	0.86	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)with 1 mM ADP	—	0.96	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (oxidized)with 1 mM ATP	—	1.38	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (oxidized)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)control (reduced) enzyme	—	0.1802	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)	—	0.2842	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)no adenine nucleotide (control)	—	0.1941	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)with 1 mM AMP	—	0.2109	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)with 1 mM ADP	—	0.2659	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	nicotinamide adenine dinucleotide (reduced)with 1 mM ATP	—	0.3347	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), nicotinamide adenine dinucleotide (reduced)
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetate	788.6	0.27	2921	pH 7.4, 25 °C	PMID 26203119	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetate
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acidcontrol (reduced) enzyme	—	0.0993	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acid	—	0.109	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acidno adenine nucleotide (control)	—	0.0973	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acidwith 1 mM AMP	—	0.0807	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acidwith 1 mM ADP	—	0.0787	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 1 (mMDH1)	Arabidopsis thaliana	oxaloacetic acidwith 1 mM ATP	—	0.0553	—	pH 7.5, 25 °C	PMID 26946085	Open record: mitochondrial malate dehydrogenase 1 (mMDH1), oxaloacetic acid
mitochondrial malate dehydrogenase 2 (mMDH2)	Arabidopsis thaliana	2-ketoglutarate	47.3	6.97	6.8	pH 7.4, 25 °C	PMID 26203119	Open record: mitochondrial malate dehydrogenase 2 (mMDH2), 2-ketoglutarate
mitochondrial malate dehydrogenase 2 (mMDH2)	Arabidopsis thaliana	oxaloacetate	167	1.02	163	pH 7.4, 25 °C	PMID 26203119	Open record: mitochondrial malate dehydrogenase 2 (mMDH2), oxaloacetate
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	(S)-malate	—	0.8	—	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, (S)-malate
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	2-hydroxy-3-oxosuccinate	297	0.035	8.5 × 10³ calc.	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, 2-hydroxy-3-oxosuccinate
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	meso-tartrate	1.32	1.12	1.20 calc.	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, meso-tartrate
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	NAD+cosubstrate meso-tartrate	—	0.158	—	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, NAD+
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	NAD+cosubstrate L-malate	—	0.3	—	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, NAD+
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	NADHcosubstrate 2-keto-3-hydroxysuccinate	—	0.024	—	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, NADH
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	NADHcosubstrate oxalacetate	—	0.016	—	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, NADH
mitochondrial malate dehydrogenase mitochondrial isozyme	Sus scrofa (pig heart)	oxaloacetate	580	0.04	1.5 × 10⁴ calc.	pH 8, 25 °C	PMID 475389	Open record: mitochondrial malate dehydrogenase mitochondrial isozyme, oxaloacetate
MjMDH ((S)-malate dehydrogenase)	Methanocaldococcus jannaschii	(2S,3S)-tartrate1 mM NAD; cosubstrate NAD	0.2	11	0.018	pH 10, 50 °C	PMID 19555779	Open record: MjMDH ((S)-malate dehydrogenase), (2S,3S)-tartrate
MjMDH ((S)-malate dehydrogenase)	Methanocaldococcus jannaschii	(2S,3S)-tartrate1 mM NADP; cosubstrate NADP	0.15	5.1	0.029	pH 10, 50 °C	PMID 19555779	Open record: MjMDH ((S)-malate dehydrogenase), (2S,3S)-tartrate
MjMDH ((S)-malate dehydrogenase)	Methanocaldococcus jannaschii	(S)-malate1 mM NAD; cosubstrate NAD	0.33	0.41	0.8	pH 10, 50 °C	PMID 19555779	Open record: MjMDH ((S)-malate dehydrogenase), (S)-malate
MjMDH ((S)-malate dehydrogenase)	Methanocaldococcus jannaschii	(S)-malate1 mM NADP; cosubstrate NADP	0.069	0.084	0.82	pH 10, 50 °C	PMID 19555779	Open record: MjMDH ((S)-malate dehydrogenase), (S)-malate
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	L-malate	—	0.772	—	pH 8.5	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), L-malate
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	nicotinamide adenine dinucleotide	—	0.232	—	pH 8.5	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), nicotinamide adenine dinucleotide
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	oxaloacetate	—	0.029	—	pH 6	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), oxaloacetate
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	oxaloacetate	—	0.058	—	pH 7.5	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), oxaloacetate
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	oxaloacetate	—	0.61	—	pH 9	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), oxaloacetate
soluble1 malate dehydrogenase (S1-MDH)	Spinacia oleracea	reduced nicotinamide adenine dinucleotide	—	0.0156	—	pH 7.5	PMID 5114926	Open record: soluble1 malate dehydrogenase (S1-MDH), reduced nicotinamide adenine dinucleotide